Thymoma
Therapeutic area
Oncology
Rare disease
Yes
- Definition
- A neoplasm arising from the epithelial cells of the thymus. Although thymomas are usually encapsulated tumors, they may invade the capsule and infiltrate the surrounding tissues or even metastasize to distant anatomic sites. The following morphologic subtypes are currently recognized: type A, type B, type AB, metaplastic, micronodular, microscopic, and sclerosing thymoma. Thymomas type B are further subdivided into types B1, B2, and B3. Thymoma type B3 usually has the most aggressive clinical course.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Thymoma
- Therapeutic area
- Oncology
- thymoma
- B2 Thymoma
- Locally Advanced Thymoma
- primary thymic epithelial neoplasm
- primary thymic epithelial tumor
- primary thymic epithelial tumour
- Recurrent Thymoma
- Stage III Thymoma
- Stage IVA Thymoma
- Stage IVB Thymoma
- thymoma (disease)
- Thymoma and Thymic Carcinoma Stage II-III
- THYM
- Severity
- Moderate
- Endocrinology
- Hematology
- Immunology
- Oncology
Sources for recorded values
- MONDO ID
- MONDO:0006456
- Parent condition
- MONDO:0018079
Related records
Broader conditions (16)
- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Endocrine gland neoplasm
- Endocrine system disorder
- Epithelial neoplasm
- Hematologic disorder
- Hematopoietic and lymphoid system neoplasm
- Human disease
- Immune system disorder
- Neoplasm
- Neoplastic disease or syndrome
- Thymic epithelial neoplasm
- Thymus gland disorder
- Thymus neoplasm
Narrower conditions (13)
- Combined thymoma
- Cortical thymoma
- Encapsulated thymoma
- Invasive malignant thymoma
- Malignant type A thymoma
- Malignant type AB thymoma
- Noninvasive malignant thymoma
- Thymoma type A
- Thymoma type AB
- Thymoma type B
- Thymoma type B1
- Thymoma type B3
- Thymoma, familial
Trials (131)
- 177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours
- 18F FLT Imaging Studies of Treatment Response for Lung Cancer and Thymoma
- 6 vs 3 Cycles of Neoadjuvant Chemotherapy for Potentially Resectable Locally Advanced Thymic Epithelial Tumors
- A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, Malignancies
- A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies
- A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors
- A Phase II, Investigator-Initiated Exploratory Study of Sacituzumab Tirumotecan for Previously Treated Unresectable Thymic Carcinomas
- A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy
- A Prospective, Single-Center Investigation of the da Vinci SP® Surgical System in Anterior Mediastinal Disease
- A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas
- A Study of KN046 in Patients With Thymic Carcinoma Who Failed Immune Checkpoint Inhibitors
- A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers
- A Study of Sunitinib in Patients With Metastatic or Recurrent Thymic Carcinoma
- A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
- A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma
- A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic Cancer
- Abscopal Effect of Radiotherapy in Combination With rhGM-CSF for Advanced Thymic Epithelial Tumours
- Adjuvant Radiotherapy for Stage II/III Thymoma After Complete Resection
- Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma
- An Investigational Scan (MRI) in Imaging Patients With Newly-Diagnosed or Recurrent Thymoma
Drugs in development (56)
- Amrubicin Phase 2
- Amrubicin hydrochloride Phase 2
- Avelumab Phase 2
- Belinostat Phase 2
- Bevacizumab Phase 2
- Bintrafusp alfa Phase 2
- Bosutinib Phase 1
- Buparlisib Phase 2
- Buparlisib hydrochloride Phase 2
- Capecitabine Phase 1
- Carboplatin Phase 2
- Catequentinib Phase 2
- Celecoxib Phase 1
- Cetuximab Phase 2
- Cisplatin Phase 2
- Cixutumumab Phase 2
- Cyclophosphamide Phase 2
- Docetaxel Phase 2
- Domvanalimab Phase 2
- Doxorubicin Phase 1