Orthocoronavirinae infectious disease
Therapeutic area
Infectious Disease
Rare disease
No
- Definition
- Infectious disease causes by viruses in the subfamily Orthocoronavirinae (coronaviruses). In humans, coronaviruses cause respiratory tract infections that can be mild, such as some cases of the common cold (among other possible causes, predominantly rhinoviruses), and others that can be lethal, such as SARS, MERS, and COVID-19.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Orthocoronavirinae infectious disease
- Therapeutic area
- Infectious Disease
- Orthocoronavirinae infectious disease
- Coronavinae infectious disease
- Coronavirus Infection
- CORONAVIRUS INFECTIONS
- coronavirus infectious disease
- Disease mechanisms
- Acquired
Sources for recorded values
- All therapeutic areas
- Infectious Disease
Sources for recorded values
- Severity
- Severe
- MONDO ID
- MONDO:0020753
- Parent condition
- MONDO:0005718
Related records
Broader conditions (9)
- Coronaviridae infectious disease
- Disease
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Human disease
- Infectious disease
- Nidovirales infectious disease
- Primary viral infectious disease
- Viral infectious disease
Narrower conditions (3)
- COVID-19
- Middle East respiratory syndrome
- Severe acute respiratory syndrome
Trials (1,130)
- "COVID-19 and Diabetes Outcomes"
- A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19
- A Clinical Trial to Determine the Safety and Immunogenicity of Healthy Candidate MERS-CoV Vaccine (MERS002)
- A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19
- A Double-blind, Placebo-controlled Clinical Trial of Fluvoxamine for Symptomatic Individuals With COVID-19 Infection
- A Follow On Community Testing Study To Evaluate The Performance of the Lucira COVID-19 All-In-One Test Kit
- A Human Clinical Study to Collect Calibration and Performance Data for the RBA-2 Device
- A Immuno-bridging and Immunization Schedules Study of COVID-19 Vaccine (Vero Cell), Inactivated
- A Longitudinal Study of COVID-19 Sequelae and Immunity
- A Multicentre Open-label Two-arm Randomised Superiority Clinical Trial of Azithromycin Versus Usual Care In Ambulatory COVID19 (ATOMIC2)
- A Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab
- A Phase 1/2 Study to Determine Safety and Immunogenicity of Two COVID 19 Vaccines VB10.2129 (RBD Candidate) and VB10.2210 (T Cell Candidate) Previously Vaccinated in Healthy Adult Volunteers
- A Phase 1/2A, Randomized Study of a T Follicular Helper (TFH)-Targeting Genetic Vaccine Strategy Designed to Induce Broad, Durable Immune Responses
- A Phase 1b Trial to Evaluate Safety and Effect of SAR443122 on Immune System in Severe COVID-19
- A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19
- A Phase 2 Study to Evaluate the Efficacy and Safety of TNX-102 SL in Patients With Multi-Site Pain Associated With Post-Acute Sequelae of SARS-CoV-2 Infection
- A Phase 3 Study to Evaluate the Safety, Tolerability, and Immunogenicity of Multiple Production Lots and Dose Levels of BNT162b2 RNA-Based COVID-19 Vaccines Against COVID-19 in Healthy Participants
- A Phase 3b/4 Randomised Trial of 3 Doses of Protein-based Covid-19 Vaccine (SpikoGen)
- A Phase II, Controlled Clinical Study Designed to Evaluate the Effect of ArtemiC in Patients Diagnosed With COVID-19
- A Phase-I Study of a Nanoparticle-based Peptide Vaccine Against SARS-CoV-2
Approved drugs (2)
- Lexgenleucel-T
- Remdesivir
Drugs in development (34)
- ABC-294640 Phase 2
- Aloxistatin
- Azithromycin Phase 3
- Azithromycin monohydrate Phase 3
- Azoximer bromide Phase 2
- Bevacizumab Phase 2
- Budesonide Phase 3
- Colchicine Phase 2
- Conestat alfa Phase 2
- Escin Phase 2
- Favipiravir Phase 3
- Human immunoglobulin G Phase 3
- Hydroxychloroquine Phase 3
- Hydroxychloroquine sulfate Phase 3
- Interferon Phase 1
- Interferon alfa Phase 1
- Interferon alfa-2B Phase 1
- Ketamine Phase 2
- Lopinavir Phase 3
- Mefloquine Phase 2
Other linked drugs (4)
- Almitrine
- Almitrine mesylate
- Atorvastatin
- Ezetimibe