Heart failure
Therapeutic area
Cardiology
Rare disease
No
- Definition
- Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Heart failure
- Therapeutic area
- Cardiology
- heart failure
- cardiac failure
- cardiac insufficiency
- failure, heart
- heart failure
- insufficiency, Cardiac
- All therapeutic areas
- Cardiology
- Severity
- Severe
- MONDO ID
- MONDO:0005252
- Parent condition
- MONDO:0005267
Related records
Broader conditions (5)
- Cardiovascular disorder
- Disease
- Disease by body system or component
- Heart disorder
- Human disease
Narrower conditions (16)
- Acute cor pulmonale
- Advanced heart failure
- Cardio-renal syndrome
- Chronic pulmonary heart disease
- Congestive heart failure
- Cor pulmonale
- Diastolic heart failure
- High output heart failure
- Idiopathic pulmonary arterial hypertension
- Kyphoscoliotic heart disease
- Left ventricular failure
- Mild heart failure
- Moderate heart failure
- Rheumatic congestive heart failure
- Symptomatic heart failure
- Systolic heart failure
Trials (5,545)
- : Vascular Function in Health and Disease
- " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD "
- "A Nurse-led Motivational Interviewing Tailored Intervention for Improving Self Care Behaviours and Health Outcomes in Heart Failure Patients in Oman
- "ALOFT - Aliskiren Observation of Heart Failure Treatment": Efficacy and Safety of Aliskiren Added on Top of Standard Therapy in Adults (≥ 18 Years) With Stable Heart Failure
- "De Novo" Atrial Fibrillation in Patients With Heart Failure: Incidence; Predictors and Relevance.
- "ESTIMATION Study" for Endocardial Mesenchymal Stem Cells Implantation in Patients After Acute Myocardial Infarction
- "HerzCheck" - Detection of Early Heart Failure Using Telemedicine in Structurally Weak Regions
- "Hub and Satellite" Heart Failure Provider's Network Study
- "The Effect of Sleep Hygiene Training Given to Heart Failure Patients on Their HospitalAcquired Insomnia Level"
- 1 Year Post Discharge Prognostic Model From the National Heart Failure Audit (NHFA)
- 123-I mIBG (AdreView) Heart-to-Mediastinal (H/M) Ratio and SPECT Imaging on a Small Field of View-High Efficiency Cardiac SPECT System
- 123I-mIBG SPECT Imaging
- 18F-mFBG Imaging for Myocardial Sympathetic Innervation
- 3/7 Resistance Training Method in Cardiac Rehabilitation
- 30 Days and 90 Days Heart Failure Re-Admission at Komfo Anokye Teaching Hospital
- 3D Assessment of RV Function in Patients Undergoing LVAD Implantation
- ⁶⁸Ga-FAPI PET/CT for Cardiac Fibrosis in Heart Failure
- A CALIBER Study: Risk Factors for Stroke, Heart Failure, and Myocardial Infarction in Atrial Fibrillation
- A Clinical Follow-up Study of Heart Failure Patients.
- A Clinical Study Assessing the Potential of Piboserod for the Treatment of Heart Failure
Approved drugs (42)
- Acetazolamide
- Alteplase
- Amlodipine besylate
- Atorvastatin calcium
- Bumetanide
- Candesartan cilexetil
- Captopril
- Carvedilol
- Chlorothiazide
- Chlorthalidone
- Conivaptan hydrochloride
- Dapagliflozin
- Dapagliflozin propanediol
- Digoxin
- Doxorubicin hydrochloride
- Empagliflozin
- Enalapril maleate
- Eplerenone
- Fosinopril sodium
- Furosemide
Drugs in development (194)
- Acipimox Phase 2
- Aladorian Phase 2
- Alagebrium chloride Phase 2
- Albuterol Phase 3
- Aliskiren Phase 3
- Allopurinol Phase 2
- Alprostadil Phase 3
- Amiodarone Phase 3
- Amiodarone hydrochloride Phase 3
- Amlodipine Phase 3
- Anakinra Phase 2
- Apixaban Phase 2
- Arginine Phase 3
- Ascorbic acid Phase 3
- Aspirin Phase 3
- Atenolol Phase 3
- Atorvastatin Phase 2
- AVE8134 Phase 2
- Balcinrenone Phase 1
- Baxdrostat Phase 3
Other linked drugs (21)
- Aldosterone
- Apelin
- Deslanoside
- Digitoxin
- Dopexamine
- Edoxaban
- Etomoxir
- Fentanyl
- Genistein
- GLP-1
- Ilepatril
- Lidocaine
- Olprinone
- Oseltamivir
- Oxypurinol
- Paricalcitol
- Phenylephrine
- Pramipexole dihydrochloride
- Prinoxodan
- Terbutaline