Gastroesophageal junction adenocarcinoma
Therapeutic area
Gastroenterology
Rare disease
No
- Definition
- A carcinoma that arises from glandular epithelial cells of the esophagogastric junction.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Gastroesophageal junction adenocarcinoma
- Therapeutic area
- Gastroenterology
- gastroesophageal junction adenocarcinoma
- adenocarcinoma - GEJ
- adenocarcinoma of cardioesophageal junction
- adenocarcinoma of gastroesophageal junction
- adenocarcinoma of the EG junction
- adenocarcinoma of the GE junction
- adenocarcinoma of the cardioesophageal junction
- adenocarcinoma of the esophagogastric junction
- adenocarcinoma of the gastroesophageal junction
- esophagogastric junction adenocarcinoma
- gastroesophageal junction adenocarcinoma
- esophagogastric adenocarcinoma
- Severity
- Severe
- Gastroenterology
- Oncology
- MONDO ID
- MONDO:0003219
- Parent condition
- MONDO:0004970
Related records
Broader conditions (16)
- Adenocarcinoma
- Cancer
- Cancer or benign tumor
- Carcinoma
- Digestive system cancer
- Digestive system carcinoma
- Digestive system disorder
- Digestive system neoplasm
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Epithelial neoplasm
- Glandular cell neoplasm
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
Trials (375)
- 64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer
- A Clinical Study of Iparomlimab and Tuvonralimab Combined With SOX Following Heterogeneous Radiotherapy as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Gastric or Gastroesophageal Junction Adenocarcinoma
- A Clinical Trial of the Safety and Anti-Tumor Activity of AB-201 in Subjects With Advanced HER2+ Solid Tumors
- A Multi-center, Two-arm, Phase 2 Clinical Study on the Perioperative Treatment of HER2-positive Resectable Esophagogastric Junctional Adenocarcinoma With Nabulimab Combined With FLOT and Trastuzumab VS FLOT Combined With Trastuzumab
- A Multicenter Cancer Biospecimen Collection Study
- A Multicenter Randomized Controlled Phase II Trial of Iparomlimab and Tuvonralimab (QL1706) Combined With SOX Chemotherapy Versus Chemotherapy Alone in the Treatment of Locally Advanced Gastric or Gastroesophageal Junction Adenocarcinoma
- A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors
- A Phase 1/1b of RNDO-564 Single Agent or in Combination With Pembrolizumab in Bladder Cancer and Other Solid Tumors Associated With Nectin-4
- A Phase 1b/2 Clinical Trial Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AUR103 Calcium in Patients With HER2-positive Advanced Gastric/Gastroesophageal Junction Adenocarcinoma
- A Phase 2 Study of Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Junction (GEJ) Cancer
- A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer
- A Phase Ib Trial Evaluating the Safety and Activity of Neoadjuvant Combination of Tislelizumab Plus FLOT for Resectable Esophagogastric Adenocarcinoma
- A Phase II Clinical Study Evaluating SSGJ-706 in Combination Therapy for Advanced Gastrointestinal Cancers
- A Phase III Clinical Study of Cadonilimab Plus SOX as Perioperative Treatment for Patients With Resectable G/GEJ Adenocarcinoma
- A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
- A Prospective Clinical Study of Transthoracic Single-hole Assisted Laparoscopic Radical Gastrectomy for Siewert Ⅱ AEG
- A Prospective Study of Apatinib Plus Concurrent Neoadjuvant Chemoradiotherapy for Siewert II ,III of Locally Advanced HER-2 Negative Adenocarcinoma at Gastroesophageal Junction
- A Safety Study of SGN-2FF for Patients With Advanced Solid Tumors
- A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection
- A Study Comparing BL-M05D1 With the Investigator's Choice of Treatment Regimen in Patients With Claudin (CLDN)18.2-Positive Advanced Gastric Cancer or Gastroesophageal Junction Adenocarcinoma (GC/GEJC) Who Have Received Prior First-Line Treatment
Approved drugs (4)
Drugs in development (51)
- Adebrelimab Phase 2
- Albumin human Phase 2
- AMG-337 Phase 1
- Atezolizumab Phase 1
- Bevacizumab Phase 2
- Cadonilimab Phase 3
- Camrelizumab Phase 2
- Cantuzumab ravtansine Phase 2
- Capecitabine Phase 3
- Carboplatin Phase 2
- Cisplatin Phase 3
- Cobimetinib Phase 1
- Cyclophosphamide Phase 3
- Envafolimab Phase 2
- Epirubicin Phase 2
- Fexagratinib Phase 2
- Fludarabine Phase 1
- Fruquintinib Phase 1
- Ganetespib Phase 1
- Gemcitabine Phase 2