Focal epilepsy
Therapeutic area
Neurology
Rare disease
No
- Definition
- A seizure caused by a localized disorder.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Focal epilepsy
- Therapeutic area
- Neurology
- focal epilepsy
- partial epilepsy
- Refractory Focal Epilepsy
- Refractory Partial Epilepsy
- All therapeutic areas
- Neurology
Sources for recorded values
- Severity
- Severe
- MONDO ID
- MONDO:0005384
- Parent condition
- MONDO:0005027
Related records
Broader conditions (7)
- Brain disorder
- Central nervous system disorder
- Disease
- Disease by body system or component
- Epilepsy
- Human disease
- Nervous system disorder
Narrower conditions (44)
- Acquired sleep-related hypermotor epilepsy
- Autosomal dominant epilepsy with auditory features
- Autosomal dominant nocturnal frontal lobe epilepsy 1
- Autosomal dominant nocturnal frontal lobe epilepsy 2
- Autosomal dominant nocturnal frontal lobe epilepsy 3
- Autosomal dominant nocturnal frontal lobe epilepsy 4
- Autosomal dominant nocturnal frontal lobe epilepsy 5
- Childhood occipital visual epilepsy
- Childhood-onset self-limited focal epilepsy syndrome
- Combined generalized and focal epilepsy
- Complex partial epilepsy
- Epilepsy with auditory features
- Epilepsy, familial focal, with variable foci 1
- Epilepsy, familial focal, with variable foci 2
- Epilepsy, familial focal, with variable foci 3
- Epilepsy, familial focal, with variable foci 4
- Epilepsy, familial temporal lobe, 1
- Familial focal epilepsy with variable foci
- Familial mesial temporal lobe epilepsy
- Familial partial epilepsy
Trials (266)
- A 19-week Cognition Study of Levetiracetam in Children With Partial Onset Seizures
- A Clinical Study on the Efficacy and Safety of Zonisamide as a First Add-On Treatment in Epileptic Seizures
- A Double-blind Confirmatory Trial of Levetiracetam in Epilepsy Patients With Partial Onset Seizures
- A Double-Blind, Randomized, Placebo-Controlled, Phase 2 Trial of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset Seizures
- A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures
- A New Method for Delineation of Epileptic Brian Tissue During Epilepsy Surgery (The HFO Study)
- A Pediatric Drug Study to Determine the Long-term Safety and Tolerability in Children and Adolescents (4-17 Years in Age) Taking the Drug
- A Phase III Open-Label Extension Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures
- A Phase III Open-Label Study Of Gabapentin As Adjunctive Therapy In Japanese Pediatric Patients With Partial Seizures
- A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy
- A Placebo-controlled Study of Levetiracetam In Children (1mo to 4yrs of Age) With Partial Onset Seizures.
- A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patients With Partial Onset Seizures (Study E2090-E044-410) (ZOOM)
- A Post-marketing Study Evaluating Eslicarbazepine Acetate (ESL) as Adjunctive Treatment in Partial-Onset Seizures (Study E2093-E044-404) (EPOS)
- A Prospective, Observational Study On The Effectiveness Of New Antiepileptic Drugs As First Bitherapy In The Daily Clinical Practice
- A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures
- A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)
- A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures
- A Safety, Efficacy, and Tolerability Trial of Pregabalin as Add-On Treatment in Pediatric Subjects <4 Years of Age With Partial Onset Seizures.
- A Study of Brivaracetam in Subjects With Partial Onset Seizures
- A Study of Lu AG06466 in Participants With Treatment Resistant Focal Epilepsy
Approved drugs (6)
- Carbamazepine
- Lacosamide
- Lamotrigine
- Perampanel
- Vigabatrin
- Zonisamide
Drugs in development (20)
- Azetukalner Phase 2
- Belnacasan Phase 2
- Brivaracetam Phase 3
- Carisbamate Phase 3
- Cenobamate Phase 3
- Diazepam Phase 3
- Eslicarbazepine acetate Phase 3
- Gabapentin Phase 3
- Ganaxolone Phase 2
- Ibuprofen Phase 2
- Levetiracetam Phase 3
- Natalizumab Phase 2
- Nifedipine Phase 2
- Oxcarbazepine Phase 3
- Padsevonil Phase 2
- Pregabalin Phase 3
- Probenecid Phase 2
- Seletracetam Phase 2
- Topiramate Phase 3
- Valproic acid Phase 1
Other linked drugs (2)
- Ezogabine
- Fluoxetine