Cutaneous lupus erythematosus
Therapeutic area
Immunology
Rare disease
No
- Definition
- An autoimmune disorder that manifests as different lupus-specific skin disorders; it can occur with systemic lupus erythematosus, or as a singular disease.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Cutaneous lupus erythematosus
- Therapeutic area
- Immunology
- cutaneous lupus erythematosus
- lupus erythematosus, cutaneous
- Severity
- Moderate
- Immunology
- Rheumatology
- MONDO ID
- MONDO:0005282
- Parent condition
- MONDO:0004670
Related records
Broader conditions (8)
- Autoimmune disease
- Connective tissue disorder
- Disease
- Disease by body system or component
- Human disease
- Immune system disorder
- Lupus erythematosus
- Rheumatic disorder
Narrower conditions (12)
- Bullous systemic lupus erythematosus
- Chilblain lupus
- Chilblain lupus 1
- Chilblain lupus 2
- Chronic cutaneous lupus erythematosus
- Discoid lupus erythematosus
- Familial chilblain lupus
- Hypertrophic or verrucous lupus erythematosus
- Lupus erythematosus panniculitis
- Lupus erythematosus tumidus
- Rowell syndrome
- Subacute cutaneous lupus erythematosus
Trials (63)
- A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
- A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus
- A Multiple Dose Study Of PD-0360324 In Patients With Active Cutaneous Lupus Erythematosus
- A Non-drug Study Profiling Cutaneous Lupus
- A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants
- A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus
- A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease
- A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)
- A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus
- A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus
- A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers
- A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus
- A Study on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SHR-7012 in Healthy Adults
- A Study to Assess the Safety and Drug Levels of BMS-986256 in Participants With Active Cutaneous Lupus Erythematosus
- A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE)
- A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE)
- A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis
- A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus
- A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms.
Drugs in development (25)
- Afimetoran Phase 1
- Alitretinoin Phase 2
- AMG-557 Phase 1
- Anifrolumab Phase 3
- Dazukibart Phase 2
- Deucravacitinib Phase 2
- Dovramilast Phase 2
- Eclitasertib Phase 2
- Edecesertib Phase 2
- Enpatoran Phase 1
- Ergocalciferol Phase 2
- Etanercept Phase 2
- Filgotinib Phase 2
- Fumaric acid Phase 2
- Human immunoglobulin G Early phase 1
- Hydroxychloroquine Phase 3
- Hydroxychloroquine sulfate Phase 3
- Lanraplenib Phase 2
- Litifilimab Phase 3
- Mocravimod Phase 2
Other linked drugs (2)
- Imiquimod
- Tapinarof