Colorectal cancer
Therapeutic area
Gastroenterology
Rare disease
Yes
- Definition
- A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma.
- Genetic basis
- Yes
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Colorectal cancer
- Therapeutic area
- Gastroenterology
- colorectal cancer
- cancer of colorectum
- cancer of large bowel
- cancer of large intestine
- cancer of the large bowel
- colon cancer, advanced, somatic
- colon cancer, somatic
- colorectal cancer
- colorectal cancer with chromosomal instability, somatic
- colorectal cancer, autosomal dominant, somatic mutation
- colorectal cancer, somatic
- colorectal cancer, susceptibility to, autosomal dominant, somatic mutation
- colorectum cancer
- malignant colorectal neoplasm
- malignant colorectal tumor
- malignant colorectal tumour
- malignant colorectum neoplasm
- malignant large bowel neoplasm
- malignant large bowel tumor
- malignant large bowel tumour
- malignant large intestine neoplasm
- malignant large intestine tumor
- malignant large intestine tumour
- malignant neoplasm of colorectum
- malignant neoplasm of large bowel
And 12 more, listed on the interactive page.
- Severity
- Severe
- Gastroenterology
- Oncology
- MONDO ID
- MONDO:0005575
- Parent condition
- MONDO:0005335
Related records
Broader conditions (16)
- Cancer
- Cancer or benign tumor
- Colorectal neoplasm
- Digestive system cancer
- Digestive system disorder
- Digestive system neoplasm
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Human disease
- Intestinal cancer
- Intestinal disorder
- Intestinal neoplasm
- Large intestine disorder
- Neoplasm
- Neoplastic disease or syndrome
Narrower conditions (106)
- Adenosquamous colon carcinoma
- Anal canal adenocarcinoma
- Anal canal carcinoma
- Anal canal carcinoma in situ
- Anal canal neuroendocrine neoplasm
- Anal canal Paget disease
- Anal canal squamous cell carcinoma
- Anal carcinoma
- Anal gland adenocarcinoma
- Anal margin basal cell carcinoma
- Anal margin carcinoma
- Anal margin squamous cell carcinoma
- Anal melanoma
- Anal mucinous adenocarcinoma
- Anal Paget disease
- Anal squamous cell carcinoma
- Anal verrucous carcinoma
- Anus adenocarcinoma
- Anus basaloid carcinoma
- Anus cancer
Trials (4,678)
- - IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases
- ¡Salud! Por la Vida (SPLV) A Colorectal Screening Promotion Program
- "Cancersensor" Chemotherapy
- "Cancersensor" Metastasis Resection
- "Cancersensor": Circadian Rhythms
- "High Levels of EMT-TFs for the Diagnosis of Colorectal Cancer (CRC)"
- "The Impact of Immunonutrition on Gut Microbiota-related Aspects in Colorectal Cancer and Gastric Cancer Patients"
- "Touch 2 Screen" Multi-media Colorectal Cancer Screening Intervention
- [18F]FLT-PET as a Predictive Imaging Biomaker of Treatment Responses to Regorafenib
- [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
- [68Ga]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR)
- [68Ga]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications
- [68Ga]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant Therapy
- #CuttingCRC: Barbershop-Based Trial & Colorectal Cancer
- #iBeatCRC: A Community-based Intervention to Increase Early-onset Colorectal Cancer Awareness
- 131-I-TM-601 Study in Adults With Solid Tumors
- 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors
- 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors
- 18F-Fluoroazomycin Arabinoside PET-CT in Diagnosing Solid Tumors in Patients
- 18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors
Approved drugs (14)
- Aflibercept
- Bevacizumab
- Capecitabine
- Cetuximab
- Encorafenib
- Fruquintinib
- Ipilimumab
- Levoleucovorin
- Levoleucovorin calcium
- Nivolumab
- Panitumumab
- Regorafenib
- Tipiracil hydrochloride
- Trifluridine
Drugs in development (359)
- 6-O-benzylguanine Phase 2
- 7-ethyl-10-hydroxycamptothecin Phase 2
- A33 131I Phase 1
- Abemaciclib Phase 1
- ABGN-107 Phase 1
- Abituzumab Phase 2
- ABT-751 Phase 2
- Adagrasib Phase 1
- Adebrelimab Phase 1
- Adecatumumab Phase 2
- Aldesleukin Phase 1
- Alpelisib Phase 2
- AMG-820 Phase 1
- Amifostine Phase 2
- AMP-224 Phase 1
- Anpocogin Phase 2
- Arfolitixorin Phase 3
- Arsenic trioxide Phase 1
- Artesunate Phase 2
- Ascorbic acid Phase 3
Other linked drugs (15)
- Anamorelin hydrochloride
- Aprepitant
- Atorvastatin
- Bempegaldesleukin
- Eltanexor
- Fosaprepitant
- Iohexol
- Izorlisib
- Ketamine
- MGD-007
- Nacolomab tafenatox
- Necitumumab
- Ropivacaine hydrochloride
- Tyrosine
- Zenocutuzumab