Bipolar disorder
Therapeutic area
Psychiatry
Rare disease
No
- Definition
- A disorder of the brain that causes unusual shifts in mood, energy, activity levels and the ability to carry out day-to-day tasks. Often these moods range and shift from periods of elation and energized behavior to those of hopelessness and depression.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Bipolar disorder
- Therapeutic area
- Psychiatry
- bipolar disorder
- Bipolar Disorder, Current Episode Manic Severe With Psychotic Features
- Bipolar Disorder, Currently in Remission
- Bipolar Disorder, Depressed
- Bipolar Disorder, Mania
- Bipolar Disorder, Manic
- Bipolar Disorder, NOS
- Bipolar Disorder, Pediatric
- Bipolar Disorder, Recovery
- Bipolar Disorders
- major affective disorder
- Manic Depression
- Manic Disorder
- manic-depression
- bipolar depression
- bipolar disorder manic phase
- manic bipolar affective disorder
- manic bipolar I disorder
- manic depressive disorder
- mixed bipolar disorder
- MAFD
- Severity
- Severe
- Neurology
- Psychiatry
Sources for recorded values
- MONDO ID
- MONDO:0004985
- Parent condition
- MONDO:0005371
Related records
Broader conditions (10)
- Brain disorder
- Central nervous system disorder
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Human disease
- Mental disorder
- Mood disorder
- Nervous system disorder
- Psychiatric disorder
Narrower conditions (13)
- Bipolar depression
- Bipolar I disorder
- Bipolar II disorder
- Major affective disorder 1
- Major affective disorder 2
- Major affective disorder 3
- Major affective disorder 4
- Major affective disorder 5
- Major affective disorder 6
- Major affective disorder 7
- Major affective disorder 8
- Major affective disorder 9
- Manic bipolar affective disorder
Trials (1,712)
- 'Thriving With Bipolar Disorder': Co-design and Evaluation of a Peer-Led Education Program Focused on Quality of Life
- "MenPhys: Intervention Protocol for Physical Wellness in Mental Health"
- "Mindfulness vs Psychoeducation in Bipolar Disorder"
- "Pilot Study of Music Intervention for Recovery of People With Severe Mental Disorder in the Community"
- 12 Week Study of the Safety/Efficacy of Asenapine When Added to Lithium/Valproate in the Treatment of Bipolar Disorder (A7501008 / P05844 / MK-8274-017)
- 12- Week Open Label Treatment of Refractory Bipolar Depression
- 12-Month Extension Study of Dialectical Behavior Therapy for Youth With Bipolar Disorder
- 12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression
- 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression
- 18F-DOPA PET to Elucidate the Antidepressant Mechanism of Lurasidone in Bipolar Disorder
- 2-Year Study of Vagus Nerve Stimulation for Higher-Grade Treatment-Resistant Depression: Clinical Outcomes and Policy Recommendation
- 3-Week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07008)
- 3-week Study of Asenapine, Olanzapine and Placebo for Treatment of Bipolar Mania (P07009)
- 3-week Study to Evaluate Efficacy and Safety of Ziprasidone With Either Lithium or Divalproex in Acutely Manic Subjects
- 40 Week Extension Study Of Asenapine and Olanzapine For Bipolar Disorder (A7501007)(COMPLETED)(P05857)
- 40 Week Trial to Study the Safety of Asenapine When Added to Lithium or Valproate in the Treatment of Bipolar Disorder (A7501009)(P05786)
- 8 Week Multi-site Study of MYDAYIS® for Bipolar Depression
- 9 Week Extension Study of Asenapine and Olanzapine in Treatment of Mania (P07007)(COMPLETED)
- A 12-weeks Study to Evaluate the Dietary Fiber and Probiotics Treatment in Prevention and Intervention of Weight-gain and Cognitive Impairment of Schizophrenia or Bipolar Disorder
- A Biological Signature for the Early Differential Diagnosis of Psychosis
Approved drugs (24)
- Acetophenazine
- Acetophenazine maleate
- Aripiprazole
- Asenapine
- Asenapine maleate
- Carbamazepine
- Cariprazine hydrochloride
- Divalproex sodium
- Doxepin hydrochloride
- Fluoxetine hydrochloride
- Lamotrigine
- Levomepromazine
- Lithium carbonate
- Lithium citrate
- Loxapine
- Loxapine hydrochloride
- Lurasidone hydrochloride
- Olanzapine
- Quetiapine fumarate
- Risperidone
Drugs in development (168)
- ABX-002 Phase 2
- Acetylcarnitine Phase 2
- Acetylcysteine Phase 2
- Alcohol Phase 2
- Aldesleukin Phase 2
- Allopurinol Phase 3
- Amisulpride Phase 2
- Aspirin Phase 3
- Aticaprant Phase 2
- Azetukalner Phase 3
- Bezafibrate Phase 2
- Bifeprunox Phase 3
- Bifeprunox mesylate Phase 3
- Bifidobacterium SPP. Phase 2
- Brexpiprazole Phase 3
- Brilaroxazine Phase 1
- Bupropion Phase 1
- Bupropion hydrochloride Phase 3
- Calcium Phase 2
- Candesartan Early phase 1
Other linked drugs (24)
- Amitriptyline
- Benzodepa
- Benzodiazepine
- Cholecalciferol
- Desvenlafaxine
- Doxepin
- Dulaglutide
- Duloxetine
- Empagliflozin
- Escitalopram oxalate
- Fluvoxamine
- Galantamine
- Mirtazapine
- Norepinephrine
- Nortriptyline
- Olsalazine sodium
- Oxcarbazepine
- Perphenazine
- Prazosin
- Semaglutide