Sodium lactate
Highest phase reached
Approved
Drug type
Small molecule
First approval year
1982
- First approval year
- 1982
- Listing at source
- Listed
- Highest phase reached
- Approved
- Drug type
- Small molecule
- Drug name
- Sodium lactate
- Molecular weight
- 112.06
- Structure (SMILES)
- CC(O)C(=O)[O-].[Na+]
- sod lact co
- Sod lact co
- compound solution of sodium lactate
- Compound solution of sodium lactate
- compound solution of sodium lactate [INN]
- compound solution of sodium lactate inn
- e 325
- E-325
- e325
- E325
- ins 325
- ins no 325
- INS NO.325
- INS-325
- natrum lacticum
- Natrum lacticum
- NATRUM LACTICUM [HPUS]
- natrum lacticum hpus
- nsc 31718
- NSC-31718
- propanoic acid 2 hydroxy monosodium salt
- PROPANOIC ACID, 2-HYDROXY-, MONOSODIUM SALT
- Sodium (lactate) anhydrous
- sodium dl lactate
- Sodium dl-lactate
- sodium lactate
- Sodium lactate
And 27 more, listed on the interactive page.
- CAS registry numbers
- 72-17-3
- ChEMBL ID
- CHEMBL1357
- InChIKey
- NGSFWBMYFKHRBD-UHFFFAOYSA-M
- PubChem compound IDs
- 23666456
- RxNorm IDs (RxCUI)
- 56489
- FDA ingredient codes (UNII)
- TU7HW0W0QT
- Applicant
- BAXTER HLTHCARE
- Approval date
- 22 Mar 1971
- Application number
- NDA016682
- First in class
- No
- Orphan designation
- No
- Availability
- Prescription only
- United States (FDA)
- Approved
Administration routes
- Parenteral
- Condition
- Pancreatitis
- Highest recorded phase
- 3
- Condition identifier
- EFO:0000278
- Subject identifier
- D010195
- Condition
- Cardiovascular Diseases
- Highest recorded phase
- 1
- Condition identifier
- EFO:0000319
- Subject identifier
- D002318
- Condition
- Wounds and Injuries
- Highest recorded phase
- 2
- Condition identifier
- EFO:0000546
- Subject identifier
- D014947
- Condition
- Stroke
- Highest recorded phase
- 2
- Condition identifier
- EFO:0000712
- Subject identifier
- D020521
- Condition
- Subarachnoid Hemorrhage
- Highest recorded phase
- 3
- Condition identifier
- EFO:0000713
- Subject identifier
- D013345
- Condition
- Scleroderma, Systemic
- Highest recorded phase
- 2
- Condition identifier
- EFO:0000717
- Subject identifier
- D012595
- Condition
- Virus Diseases
- Highest recorded phase
- 1
- Condition identifier
- EFO:0000763
- Subject identifier
- D014777
- Condition
- Reperfusion Injury
- Highest recorded phase
- 2
- Condition identifier
- EFO:0002687
- Subject identifier
- D015427
- Condition
- Heart Failure
- Highest recorded phase
- 3
- Condition identifier
- EFO:0003144
- Subject identifier
- D006333
- Condition
- Severe Dengue
- Highest recorded phase
- 3
- Condition identifier
- EFO:0004227
- Subject identifier
- D019595
- Condition
- Hearing Loss
- Highest recorded phase
- 1
- Condition identifier
- EFO:0004238
- Subject identifier
- D034381
- Condition
- Postoperative Nausea and Vomiting
- Highest recorded phase
- 2
- Condition identifier
- EFO:0004888
- Subject identifier
- D020250
- Condition
- Hypotension
- Highest recorded phase
- 0.5
- Condition identifier
- EFO:0005251
- Subject identifier
- D007022
- Condition
- Shock, Septic
- Highest recorded phase
- 2
- Condition identifier
- EFO:0006834
- Subject identifier
- D012772
- Condition
- Intestinal Diseases
- Highest recorded phase
- 2
- Condition identifier
- EFO:0009431
- Subject identifier
- D007410
- Condition
- Burns
- Highest recorded phase
- 3
- Condition identifier
- EFO:0009516
- Subject identifier
- D002056
- Condition
- Pancreatitis
- Highest recorded phase
- 3
- Condition identifier
- EFO:1000652
- Subject identifier
- D010195
- Condition
- Hypovolemia
- Highest recorded phase
- 3
- Condition identifier
- HP:0011106
- Subject identifier
- D020896
- Condition
- Shock
- Highest recorded phase
- 3
- Condition identifier
- HP:0031273
- Subject identifier
- D012769
- Condition
- Depressive Disorder, Major
- Highest recorded phase
- 2
- Condition identifier
- MONDO:0002009
- Subject identifier
- D003865
- Condition
- Cataract
- Highest recorded phase
- 2
- Condition identifier
- MONDO:0005129
- Subject identifier
- D002386
- Condition
- Prostatic Neoplasms, Castration-Resistant
- Highest recorded phase
- 2
- Condition identifier
- MONDO:0008315
- Subject identifier
- D064129
- Condition identifier
- EFO_0000278
- Highest recorded phase
- 3
- Condition identifier
- EFO_0000546
- Condition identifier
- EFO_0000712
- Highest recorded phase
- 2
- Condition identifier
- EFO_0000713
- Highest recorded phase
- 3
- Condition identifier
- EFO_0000717
- Highest recorded phase
- 2
- Condition identifier
- EFO_0000763
- Highest recorded phase
- 1
- Condition identifier
- EFO_0002687
- Condition identifier
- EFO_0003144
- Highest recorded phase
- 3
- Condition identifier
- EFO_0003776
- Highest recorded phase
- 3
- Condition identifier
- EFO_0004227
- Highest recorded phase
- 3
- Condition identifier
- EFO_0004238
- Condition identifier
- EFO_0005251
- Condition identifier
- EFO_0006834
- Highest recorded phase
- 3
- Condition identifier
- EFO_0009431
- Highest recorded phase
- 2
- Condition identifier
- EFO_0009516
- Highest recorded phase
- 3
- Condition identifier
- EFO_0009636
- Condition identifier
- EFO_0011023
- Condition identifier
- EFO_1000014
- Condition identifier
- EFO_1000652
- Highest recorded phase
- 3
- Condition identifier
- HP_0001941
- Highest recorded phase
- 4
- Condition identifier
- HP_0002637
- Highest recorded phase
- 3
- Condition identifier
- HP_0011106
- Highest recorded phase
- 3
- Condition identifier
- HP_0031273
- Highest recorded phase
- 3
- Condition identifier
- HP_0100806
- Highest recorded phase
- 3
- Condition identifier
- MONDO_0000440
- Highest recorded phase
- 3
And 18 more, listed on the interactive page.
- Event
- abdominal distension
- Reports
- 392
- Reporting signal score
- 519.961
- Event
- abdominal pain
- Reports
- 345
- Reporting signal score
- 96.7731
- Event
- bloody peritoneal effluent
- Reports
- 183
- Reporting signal score
- 941.73
- Event
- device interaction
- Reports
- 66
- Reporting signal score
- 305.539
- Event
- diabetic foot
- Reports
- 42
- Reporting signal score
- 110.9
- Event
- dizziness
- Reports
- 48
- Reporting signal score
- 137.173
- Event
- drug interaction
- Reports
- 4
- Reporting signal score
- 120.935
- Event
- fatigue
- Reports
- 34
- Reporting signal score
- 272.839
- Event
- fluid imbalance
- Reports
- 27
- Reporting signal score
- 96.7624
- Event
- fluid overload
- Reports
- 419
- Reporting signal score
- 1,188.61
- Event
- fluid retention
- Reports
- 149
- Reporting signal score
- 138.456
- Event
- fungal peritonitis
- Reports
- 186
- Reporting signal score
- 901.472
- Event
- headache
- Reports
- 31
- Reporting signal score
- 215.66
- Event
- hernia
- Reports
- 99
- Reporting signal score
- 174.094
- Event
- hypervolaemia
- Reports
- 133
- Reporting signal score
- 502.627
- Event
- infectious peritonitis
- Reports
- 34
- Reporting signal score
- 120.121
- Event
- inguinal hernia
- Reports
- 65
- Reporting signal score
- 128.194
- Event
- noninfectious peritonitis
- Reports
- 42
- Reporting signal score
- 188.709
- Event
- peritoneal cloudy effluent
- Reports
- 70
- Reporting signal score
- 352.733
- Event
- peritoneal dialysis complication
- Reports
- 399
- Reporting signal score
- 2,045.93
- Event
- peritoneal disorder
- Reports
- 54
- Reporting signal score
- 207.46
- Event
- peritoneal effluent abnormal
- Reports
- 22
- Reporting signal score
- 109.253
- Event
- peritonitis
- Reports
- 1,425
- Reporting signal score
- 5,742.22
- Event
- peritonitis bacterial
- Reports
- 1,266
- Reporting signal score
- 6,163.44
- Event
- sepsis
- Reports
- 196
- Reporting signal score
- 114.734
And 2 more, listed on the interactive page.
- NCT00425334
- NCT00529490
- NCT00529711
- NCT01981655
- NCT02467387
- NCT00801359
- NCT00966628
- NCT00995683
- NCT02776488
- NCT01108601
- NCT01236833
- NCT01433276
- NCT04102371
- NCT02558543
- NCT02866552
- NCT02641561
- NCT03629600
- NCT04381169
- NCT02709044
- NCT02821546
- NCT02726308
- NCT05658406
- NCT02782520
- NCT02807727
- NCT03118362
And 8 more, listed on the interactive page.
- Route
- Intraperitoneal
Conditions of use
- Select mode of therapy, frequency of treatment, formulation, fill volume, duration of dwell, and length of dialysis based on the patient’s clinical condition, fluid, electrolyte and specific needs
- Prodrug
- No
- Chirality
- Racemic
- Inorganic
- No
- Heavy atoms
- 7
- Molecular formula
- C3H5NaO3
- Monoisotopic mass
- 112.01363830
- Natural product
- Yes
- 0264-2203
- 0264-7389
- 0264-7750
- 0264-7751
- 0338-0114
- 0338-0117
- 0338-0125
- 0338-0137
- 0338-0143
- 0338-0811
- 0941-0409
- 0941-0411
- 0941-0413
- 0941-0415
- 0941-0424
- 0941-0426
- 0941-0427
- 0941-0429
- 0941-0430
- 0941-0433
- 0941-0457
- 0941-0459
- 0941-0484
- 0941-0487
- 0941-0490
And 46 more, listed on the interactive page.
- Recorded assays
- 28
- Active assays
- 0
Related records
Trials (64)
- 0.5M Na Lactate Solution in Acute Heart Failure (AHF)
- A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
- A Study of hBMMSC Injection in Patients With aPAP
- A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure
- Aggressive Intravenous Hydration With Lactated Ringer's Solution for Prevention of Post-ESWL Pancreatitis
- An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy
- Balanced Crystalloids in Postpartum Hemorrhage
- Biologically Modified Saphenous Vein Transplants for Improved CABG Outcomes
- Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy
- Crystalloids Versus Colloids During Surgery
- Double Blinded Randomized Control Trial of Types of IVF in Children With DKA
- Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia
- Effect of Exogenous Lactate on Neurocognitive in Brain Trauma
- Effect of Liberal and Restrictive IV Fluids on Recovery After Gallbladder Surgery
- Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation
- Effects of BRS and LRS on Postoperative Acute Kidney Injury
- Efficacy of Steroid Supplementation After TMJ Rinsing for Pain Management
- Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock
- Evaluate the Nephrotoxicity by 6% Hydroxyethyl Starch 130/0.4 in Old Patients During Orthopaedic Surgery
- Evaluation of Endoscopic Surgical Field Clarity Using Hot Saline Versus Lactated Ringer's Irrigation
Approved for (1)
- Acidosis disorder
In development for (28)
- Acute pancreatitis Phase 3
- Brain edema Phase 3
- Brain ischemia Phase 3
- Brain neoplasm Phase 3
- Burn Phase 3
- Cardiovascular disorder Phase 1
- Cataract Phase 2
- Cerebral infarction Phase 3
- Dengue hemorrhagic fever Phase 3
- Hearing loss disorder Phase 1
- Heart failure Phase 3
- Hypotensive disorder Early phase 1
- Injury Phase 2
- Intestinal disorder Phase 2
- Intracranial hypertension Phase 3
- Ischemia reperfusion injury Phase 2
- Ischemic stroke Phase 2
- Major depressive disorder Phase 2
- Metabolic acidosis Phase 3
- Necrotizing enterocolitis Phase 2
Other linked conditions (1)
- Acute kidney injury