Neisseria meningitidis outer membrane vesicles
Highest phase reached
Approved
Drug type
Vaccine component
First approval year
2013
- First approval year
- 2013
- Listing at source
- Listed
- Highest phase reached
- Approved
- Drug type
- Vaccine component
- Drug name
- Neisseria meningitidis outer membrane vesicles
- neisseria meningitidis outer membrane vesicles component of bexsero
- Neisseria meningitidis outer membrane vesicles component of bexsero
- neisseria meningitidis outer membrane vesicles
- Neisseria meningitidis outer membrane vesicles
- ChEMBL ID
- CHEMBL6068370
- First in class
- No
- Orphan designation
- No
Mechanisms of action
- Mechanism
- Outer membrane vesicles vaccine antigen
- Action type
- VACCINE_ANTIGEN
- Target
- Outer membrane vesicles
- Condition
- Vaccination
- Highest recorded phase
- 4
- Condition identifier
- EFO:0004292
- Subject identifier
- D014611
- Condition
- Meningitis, Meningococcal
- Highest recorded phase
- 4
- Condition identifier
- EFO:1001040
- Subject identifier
- D008585
- Condition identifier
- EFO_0004249
- Condition identifier
- EFO_1001040
- Condition identifier
- MONDO_0005373
- Highest recorded phase
- 4
- Prodrug
- No
- Chirality
- Single enantiomer
- Inorganic
- No
- Natural product
- No
Related records
Trials (43)
- A Phase 3 Study to Assess the Immune Response And Safety Of Rmenb+Omv Nz In Primed Healthy Participants (10 To 20 Years Old)
- A Phase 3b Study to Assess the Safety of Novartis Meningococcal B Recombinant Vaccine When Administered in Healthy At-risk Adults
- A Phase 3B, Open Label, Multi-Center Study to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered Alone to Healthy Infants According to Different Immunization Schedules and to Healthy Children Aged 2 to 10 Years
- A Phase 3b, Single-Center, Open-label Study to Assess the Immunogenicity and Safety of Novartis Meningococcal B Recombinant Vaccine When Administered at a 0, 2-Month Schedule in Healthy At-Risk Adults Aged 18 to 65 Years Inclusive.
- A Sourcing Study to Collect Human Blood Samples From Healthy Adults
- A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age
- Assessment of Antibody Persistence at Eighteen Months After the Completion of the Vaccination Course in Study V72P10
- Baby Vaccine Study (Sched3)
- Combined Study - Phase 3b MenB Long Term Persistence in Adolescents
- Effectiveness of GlaxoSmithKline Biologicals S.A's Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults
- Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae
- Evaluation of Safety and Immunogenicity of Meningococcal B and Meningococcal ACWY Vaccine in at Risk Population
- Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of a Booster Dose of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received Three Doses of the Same Vaccine
- Extension Study Evaluating Antibody Persistence and Safety, Tolerability and Immunogenicity of Booster Doses of Novartis rMenB±OMV NZ Vaccine in Healthy UK Children Who Previously Received One or Four Doses of the Same Vaccine
- Extension Study of V72P13 to Evaluate the Safety, Tolerability and Immunogenicity of Novartis Meningococcal B Recombinant Vaccine When Administered as a Booster or as a Two-dose Catch-up to Healthy Toddlers
- Immunogenicity and Reactogenicity of a Meningococcal B Outer Membrane Vesicle Vaccine Given in a 0,6,12 Month Schedule to Health UK Adults
- Immunogenicity and Safety of MenB Vaccine in Pediatric Patients With Autoimmune Rheumatic Diseases
- Immunogenicity and Safety Study of GSK's MenABCWY Vaccine in Healthy Adolescents and Adults Previously Primed With MenACWY Vaccine
- Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination
- Novartis Vaccine and Diagnostics Carriage Trial