Dexpramipexole dihydrochloride
Highest phase reached
Phase 3
Drug type
Small molecule
- Listing at source
- Listed
- Highest phase reached
- Phase 3
- Drug type
- Small molecule
- Drug name
- Dexpramipexole dihydrochloride
- Molecular weight
- 302.27
- Structure (SMILES)
- CCCN[C@@H]1CCc2nc(N)sc2C1.Cl.Cl.O
- 2 6 benzothiazolediamine 4 5 6 7 tetrahydro n sup 6 propyl hydrochloride hydrate 1 2 1 6r
- 2,6-BENZOTHIAZOLEDIAMINE, 4,5,6,7-TETRAHYDRO-N(SUP 6)-PROPYL-, HYDROCHLORIDE, HYDRATE (1:2:1), (6R)-
- dexpramipexole dihydrochloride
- Dexpramipexole dihydrochloride
- Dexpramipexole Dihydrochloride
- DEXPRAMIPEXOLE DIHYDROCHLORIDE [USAN]
- dexpramipexole dihydrochloride monohydrate
- Dexpramipexole dihydrochloride monohydrate
- Dexpramipexole dihydrochloride monohydrate [WHO-DD]
- dexpramipexole dihydrochloride monohydrate who dd
- dexpramipexole dihydrochloride usan
- kns 760704
- kns 760704 anhydrous
- KNS-760704
- KNS-760704 ANHYDROUS
- pramipexole related compound d
- Pramipexole related compound d
- snd 919cl2x
- SND 919CL2X
- snd 919cl2x monohydrate
- SND-919CL2X
- SND-919CL2X MONOHYDRATE
- CAS registry numbers
- 908244-04-2
- ChEMBL ID
- CHEMBL2105687
- InChIKey
- APVQOOKHDZVJEX-LSBIWMFESA-N
- PubChem compound IDs
- 46174453
- FDA ingredient codes (UNII)
- 795J01AE70
- First in class
- No
- Orphan designation
- No
- Condition
- Amyotrophic Lateral Sclerosis
- Highest recorded phase
- 2
- Condition identifier
- MONDO:0004976
- Subject identifier
- D000690
- Condition
- Asthma
- Highest recorded phase
- 3
- Condition identifier
- MONDO:0004979
- Subject identifier
- D001249
- Condition identifier
- EFO_0000341
- Highest recorded phase
- 2
- Condition identifier
- MONDO_0004976
- Highest recorded phase
- 2
- Condition identifier
- MONDO_0004979
- Highest recorded phase
- 3
- NCT00931944
- NCT06388889
- Hydrogen bond acceptors
- 4
- Hydrogen bond donors
- 2
- Polar surface area
- 50.94
- Calculated partition coefficient (ALogP)
- 1.58
- Prodrug
- No
- Chirality
- Single enantiomer
- Inorganic
- No
- Rule-of-five violations
- 0
- Rotatable bonds
- 3
- Heavy atoms
- 17
- Molecular formula
- C10H21Cl2N3OS
- Monoisotopic mass
- 301.0782389
- Natural product
- No
Related records
Trials (6)
- A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma
- A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)
- A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma.
- A Study to Assess the Effects of Dexpramipexole in Participants With Eosinophilic COPD
- Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)
- Phase III Long-Term Extension Study With Dexpramipexole
In development for (3)
- Amyotrophic lateral sclerosis Phase 2
- Asthma Phase 3
- Chronic obstructive pulmonary disease Phase 2