Cemacabtagene ansegedleucel

Highest phase reached
Drug type

Listing at source
Listed
Highest phase reached

Drug type
Drug name
Cemacabtagene ansegedleucel

  • allogeneic t lymphocytes obtained from peripheral blood mononuclear cells by leukapheresis of healthy volunteer donors transduced with a self inactivating non replicating lentiviral vector encoding a chimeric antigen receptor car targeting human cd19 the cells are also genetically modified using transcription activator like tal effector nucleases that are transiently delivered into the cell as mrnas via electroporation and code for two pairs one pair is designed for disruption of the t cell receptor alpha constant trac and the other for disruption of the cd52 locus
  • Allogeneic T lymphocytes obtained from peripheral blood mononuclear cells by leukapheresis of healthy volunteer donors, transduced with a self-inactivating, non-replicating lentiviral vector encoding a chimeric antigen receptor (CAR) targeting human CD19. The cells are also genetically modified using transcription activator-like (TAL) effector nucleases that are transiently delivered into the cell as mRNAs via electroporation and code for two pairs: one pair is designed for disruption of the T-cell receptor alpha constant (TRAC) and the other for disruption of the CD52 locus
  • cemacabtagen ansegedleucel
  • Cemacabtagen ansegedleucel
  • cemacabtagene ansegedleucel
  • Cemacabtagene ansegedleucel
  • cemacabtagene ansegedleucel [INN]
  • Cemacabtagene ansegedleucel [WHO-DD]
  • cemacabtagene ansegedleucel inn
  • cemacabtagene ansegedleucel who dd

ChEMBL ID
CHEMBL5314816
FDA ingredient codes (UNII)
  • W3X22HS7XD

First in class
No
Orphan designation
No

Investigated indications

  • Condition
    Neoplasms
    Highest recorded phase
    2
    Condition identifier
    EFO:0000616
    Subject identifier
    D009369

  • Condition identifier
    EFO_0000616
  • Condition identifier
    MONDO_0004948
    Highest recorded phase
    1
  • Condition identifier
    MONDO_0005070

Prodrug
No
Chirality
Single enantiomer
Inorganic
No
Natural product
No

Related records

Trials (1)

In development for (2)