Cemacabtagene ansegedleucel
Highest phase reached
Phase 2
Drug type
Gene
- Listing at source
- Listed
- Highest phase reached
- Phase 2
- Drug type
- Gene
- Drug name
- Cemacabtagene ansegedleucel
- allogeneic t lymphocytes obtained from peripheral blood mononuclear cells by leukapheresis of healthy volunteer donors transduced with a self inactivating non replicating lentiviral vector encoding a chimeric antigen receptor car targeting human cd19 the cells are also genetically modified using transcription activator like tal effector nucleases that are transiently delivered into the cell as mrnas via electroporation and code for two pairs one pair is designed for disruption of the t cell receptor alpha constant trac and the other for disruption of the cd52 locus
- Allogeneic T lymphocytes obtained from peripheral blood mononuclear cells by leukapheresis of healthy volunteer donors, transduced with a self-inactivating, non-replicating lentiviral vector encoding a chimeric antigen receptor (CAR) targeting human CD19. The cells are also genetically modified using transcription activator-like (TAL) effector nucleases that are transiently delivered into the cell as mRNAs via electroporation and code for two pairs: one pair is designed for disruption of the T-cell receptor alpha constant (TRAC) and the other for disruption of the CD52 locus
- cemacabtagen ansegedleucel
- Cemacabtagen ansegedleucel
- cemacabtagene ansegedleucel
- Cemacabtagene ansegedleucel
- cemacabtagene ansegedleucel [INN]
- Cemacabtagene ansegedleucel [WHO-DD]
- cemacabtagene ansegedleucel inn
- cemacabtagene ansegedleucel who dd
- ChEMBL ID
- CHEMBL5314816
- FDA ingredient codes (UNII)
- W3X22HS7XD
- First in class
- No
- Orphan designation
- No
Investigated indications
- Condition
- Neoplasms
- Highest recorded phase
- 2
- Condition identifier
- EFO:0000616
- Subject identifier
- D009369
- Condition identifier
- EFO_0000616
- Condition identifier
- MONDO_0004948
- Highest recorded phase
- 1
- Condition identifier
- MONDO_0005070
- Prodrug
- No
- Chirality
- Single enantiomer
- Inorganic
- No
- Natural product
- No
Related records
Trials (1)
In development for (2)
- B-cell chronic lymphocytic leukemia Phase 1
- Neoplasm Phase 2