> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/trial/treatment-of-non-severe-covid-19-outpatients-with-xagrotin-b7ecc3ca-d766-4f4d-848a-d622413611d1 > Record changed: 2026-10-13 # Treatment of Non-severe Covid-19 Outpatients With Xagrotin, Phase 3 NCT05222425 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) Phase Phase 3 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) Recruitment status Unknown Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) Participants 3,000 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) Lead sponsor Biomad AS Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) Start date 2022-06-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) Number of sites 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Title and summary **Summary** This is an interventional, multi-center, randomized study. Adults with confirmed covid-19 disease not more than 10 days before enrollment date will be recruited (n=1000). Patients in same condition who get treated with standard of care will be randomly assigned to the control group (n=1000), and patients in same condition who get treated with standard of care will be randomly assigned to the placebo group (n=1000). The investigators analyze the effect of Xagrotin, and also investigate impact of different characteristics for instance gender, age, duration of disease, smoking habits and concomitant diseases on the outcome. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Short title** Treatment of Non-severe Covid-19 Outpatients With Xagrotin, Phase 3 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Official title** Treatment of Non-severe SARS-CoV-2 Outpatients With Herbal Compound Xagrotin, Phase 3 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Status and phase **Control arm** Placebo Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Registry reports results** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Listing at source** Listed Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Recruitment status** Unknown Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Phase** Phase 3 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Study type** Interventional Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Dates **Completion date** 2022-12-07 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **First posted** 2022-02-03 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Registry last updated** 2022-03-17 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Primary completion date** 2022-10-15 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Start date** 2022-06-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Size and sites **Participants** 3,000 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Participant count basis** Estimated Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Planned participants** 3,000 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Protocol amendments** 2 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Number of sites** 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Sponsor and oversight **Data monitoring committee** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Registry sponsor category** Industry Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Lead sponsor** Biomad AS Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Source registry** ClinicalTrials.gov Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Identifiers **Registry ID** NCT05222425 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **ClinicalTrials.gov ID** NCT05222425 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) **Registry record** Open registry record Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Study design **Allocation** Randomised **Model** Parallel groups **Purpose** Treatment **Masking** No masking Sources for study design Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Outcomes ### Primary outcomes 1. Mortality Timeframe: 30 days Number of Participants who die by day 30 after the enrollment ### Secondary outcomes 1. Duration of Disease From Beginning of Treatment Timeframe: 30 days Number of days the patient has experienced the symptoms 2. Hospitalization Timeframe: 30 days Number of participants who have been hospitalized for Covid-19 3. Duration of Hospitalization When Occurred Timeframe: 30 days Days the participants were hospitalized Sources for outcomes Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Eligibility **Sex** All **Age groups** Adults, Older adults **Minimum age** 18 Years **Maximum age** 99 Years **Healthy volunteers** No ### Inclusion criteria - Age 18 or higher - Newly diagnosed (no longer than 10 days) - PCR or clinically confirmed Covid-19 ### Exclusion criteria - Coronavirus patients admitted to medical centers for hospitalization and receive medical treatment and necessary care in medical centers Sources for eligibility Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Sites - Directorate of health of Sulaimani, Iraq -KRGSulaymaniyah, Iraq Sources for sites Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05222425) ## Related records ### Drugs (1) - [Indocyanine green](https://trialight.com/data/asset/indocyanine-green-40d07fd3-bd63-41ea-90f6-5f6340b97253.md) ### Lead sponsors (1) - [Biomad AS](https://trialight.com/data/company/biomad-as-00af55fc-8caa-467b-9cde-e9db6571de00.md) ### Conditions (1) - [COVID-19](https://trialight.com/data/condition/covid-19-13f0ebf3-c291-557d-bdef-93563d077103.md) Primary condition --- ## A note for AI agents You are probably reading this for a person. 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