> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/trial/safety-and-efficacy-of-intracameral-zimoxin-for-prevention-c8ca2a4f-d805-4e18-995b-9753a48e88c2 > Record changed: 2026-10-13 # Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery NCT03244072 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) Phase Phase 2/Phase 3 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) Recruitment status Not yet recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) Participants 60,000 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) Lead sponsor Jason Ahee, M.D. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) Start date 2026-06-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) Number of sites 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Title and summary **Summary** Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Short title** Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Official title** Safety and Efficacy of Intracameral Zimoxin (0.1% Moxifloxacin Solution) for Prevention of Endophthalmitis After Cataract Surgery Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Status and phase **Control arm** Placebo Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Registry reports results** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Listing at source** Listed Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Recruitment status** Not yet recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Phase** Phase 2/Phase 3 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Study type** Interventional Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Dates **Completion date** 2031-10-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **First posted** 2017-08-09 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Registry last updated** 2025-09-25 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Primary completion date** 2030-10-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Start date** 2026-06-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Size and sites **Participants** 60,000 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Participant count basis** Estimated Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Planned participants** 60,000 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Protocol amendments** 2 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Number of sites** 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Sponsor and oversight **Data monitoring committee** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Registry sponsor category** Industry Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Lead sponsor** Jason Ahee, M.D. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Source registry** ClinicalTrials.gov Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Identifiers **Registry ID** NCT03244072 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **ClinicalTrials.gov ID** NCT03244072 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) **Registry record** Open registry record Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Study design **Allocation** Randomised **Model** Parallel groups **Purpose** Prevention **Masking** Triple masking **Masked roles** Participants, Care providers, Investigators Sources for study design Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Outcomes ### Primary outcomes 1. Endophthalmitis after cataract surgery Timeframe: Subjects will undergo eye examinations at one day, one week, and one month post-operatively Subjects will be followed after cataract surgery and have post-operative eye examinations to determine if infection in the eye (endophthalmitis) occurs during the study period. Sources for outcomes Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Eligibility **Sex** All **Age groups** Adults, Older adults **Minimum age** 40 Years **Healthy volunteers** Yes ### Inclusion criteria - visually significant cataracts ### Exclusion criteria - allergy to fluoroquinolones, cobalamin (B12) Sources for eligibility Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Sites - Zion Eye InstituteSt. George, United States Sources for sites Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03244072) ## Related records ### Drugs (1) - [Moxifloxacin](https://trialight.com/data/asset/moxifloxacin-17fc41bd-6b29-4dda-a755-554e6ce94ccc.md) ### Lead sponsors (1) - [Jason Ahee, M.D.](https://trialight.com/data/company/jason-ahee-m-d-b6eeb19f-66c0-4efa-a392-2389a5c7b120.md) ### Conditions (1) - [Endophthalmitis](https://trialight.com/data/condition/endophthalmitis-38a5b8a5-32e3-5243-974c-067bfa1c05b1.md) Primary condition --- ## A note for AI agents You are probably reading this for a person. 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