Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery

NCT03244072
clinicaltrials.gov
Phase
Phase 2/Phase 3
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Recruitment status
Not yet recruiting
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Participants
60,000
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Lead sponsor
Jason Ahee, M.D.
clinicaltrials.gov
Start date
2026-06-01
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Number of sites
1
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Summary
Intracameral injection of 0.1% moxifloxacin solution after cataract surgery to prevent endophthalmitis
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Short title
Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract Surgery
clinicaltrials.gov
Official title
Safety and Efficacy of Intracameral Zimoxin (0.1% Moxifloxacin Solution) for Prevention of Endophthalmitis After Cataract Surgery
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Control arm
Placebo
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Registry reports results
No
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Listing at source
Listed
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Recruitment status
Not yet recruiting
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Phase
Phase 2/Phase 3
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Study type
Interventional
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Completion date
2031-10-01
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First posted
2017-08-09
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Registry last updated
2025-09-25
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Primary completion date
2030-10-01
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Start date
2026-06-01
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Participants
60,000
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Participant count basis
Estimated
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Planned participants
60,000
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Protocol amendments
2
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Number of sites
1
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Data monitoring committee
No
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Registry sponsor category
Industry
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Lead sponsor
Jason Ahee, M.D.
clinicaltrials.gov
Source registry
ClinicalTrials.gov
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Registry ID
NCT03244072
clinicaltrials.gov
ClinicalTrials.gov ID
NCT03244072
clinicaltrials.gov
Registry record
Open registry record
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Allocation
Randomised
Model
Parallel groups
Purpose
Prevention
Masking
Triple masking
Masked roles
Participants, Care providers, Investigators
Sources for study design
clinicaltrials.gov

  1. Endophthalmitis after cataract surgery

    Timeframe: Subjects will undergo eye examinations at one day, one week, and one month post-operatively

    Subjects will be followed after cataract surgery and have post-operative eye examinations to determine if infection in the eye (endophthalmitis) occurs during the study period.

Sources for outcomes
clinicaltrials.gov

Sex
All
Age groups
Adults, Older adults
Minimum age
40 Years
Healthy volunteers
Yes

  • visually significant cataracts

  • allergy to fluoroquinolones, cobalamin (B12)
Sources for eligibility
clinicaltrials.gov

  • Zion Eye InstituteSt. George, United States
Sources for sites
clinicaltrials.gov

Related records

Drugs (1)

Lead sponsors (1)

Conditions (1)