> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/trial/exploratory-study-to-standard-triple-therapy-with-tegoprazan-08e03496-132d-4691-b710-8bcab47d8bf2 > Record changed: 2026-10-13 # Exploratory Study to Standard Triple Therapy With Tegoprazan(by Dose) in H. Pylori Positive Patients NCT05933031 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) Phase Phase 2 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) Recruitment status Unknown Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) Participants 381 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) Lead sponsor HK inno.N Corporation Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) Start date 2023-02-27 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) Number of sites 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Title and summary **Summary** This exploratory study is designed to compare safety and efficacy between a Tegoprazan dose-specific standard triple therapy and Lansoprazole standard triple therapy in H. pylori positive patients. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Short title** Exploratory Study to Standard Triple Therapy With Tegoprazan(by Dose) in H. Pylori Positive Patients Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Official title** A Randomized, Double-Blind, Active-controlled, Multi-center, Therapeutic Exploratory Study to Evaluate the Safety and Efficacy of a Standard Triple Therapy With Tegoprazan (by Dose) in H. Pylori Positive Patients Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Status and phase **Control arm** Active comparator Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Registry reports results** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Listing at source** Listed Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Recruitment status** Unknown Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Phase** Phase 2 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Study type** Interventional Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Dates **Completion date** 2024-12-31 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **First posted** 2023-07-06 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Registry last updated** 2023-07-06 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Primary completion date** 2024-12-31 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Start date** 2023-02-27 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Size and sites **Participants** 381 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Participant count basis** Estimated Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Planned participants** 381 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Protocol amendments** 0 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Number of sites** 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Sponsor and oversight **Data monitoring committee** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Registry sponsor category** Industry Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Lead sponsor** HK inno.N Corporation Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Source registry** ClinicalTrials.gov Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Identifiers **Registry ID** NCT05933031 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **ClinicalTrials.gov ID** NCT05933031 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) **Registry record** Open registry record Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Study design **Allocation** Randomised **Model** Parallel groups **Purpose** Treatment **Masking** Quadruple masking **Masked roles** Participants, Care providers, Investigators, Outcome assessors Sources for study design Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Outcomes ### Primary outcomes 1. H. pylori eradication rate Timeframe: 42 days Assess H. pylori eradication rate by UBT Sources for outcomes Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Eligibility **Sex** All **Age groups** Adults, Older adults **Minimum age** 19 Years **Maximum age** 75 Years **Healthy volunteers** No ### Inclusion criteria - H. pylori positive at screening - Subjects who have upper gastrointestinal disease ### Exclusion criteria - Having received prior therapy for eradication of H. pylori - Prior use of P-CAB, proton pump inhibitors (PPIs), H2 receptor blockers within 14 days - Prior use of H. pylori eradication effective antibiotics, bismuth within 28 days Sources for eligibility Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Sites - Chung-Ang University HosptialSeoul, South KoreaRecruiting Sources for sites Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## References - PubMed 41531249 Source: [pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/41531249/) Related publication Sources for references Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT05933031) ## Related records ### Drugs (2) - [Lansoprazole](https://trialight.com/data/asset/lansoprazole-1f580c6f-7852-4af6-bdcc-8a5822477b51.md) - [Tegoprazan](https://trialight.com/data/asset/tegoprazan-f2335eec-d19e-4178-aa1b-90007a8fc240.md) ### Lead sponsors (1) - [HK inno.N Corporation](https://trialight.com/data/company/hk-inno-n-corporation-f9a0c74f-5279-4d75-83ac-61eb021dde5e.md) ### Conditions (1) - [Helicobacter pylori infectious disease](https://trialight.com/data/condition/helicobacter-pylori-infectious-disease-ff5903ca-758b-5979-a633-075499e2938b.md) Primary condition ### Targets (2) - [ATP4A](https://trialight.com/data/target/atp4a-cb311620-cbd7-5592-86bf-6eff6bf5e70e.md) - [ATP4B](https://trialight.com/data/target/atp4b-dd74ece5-dac6-5730-bcb3-d26c200dd49f.md) --- ## A note for AI agents You are probably reading this for a person. 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