> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/trial/a-trial-of-shr-7782-for-treatment-of-advanced-malignant-9c8a3661-dc00-4da3-8d39-4ec3f2a5b4e9 > Record changed: 2026-10-13 # A Trial of SHR-7782 for Treatment of Advanced Malignant Tumors NCT07123129 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) Phase Phase 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) Recruitment status Recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) Participants 200 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) Lead sponsor Suzhou Suncadia Biopharmaceuticals Co., Ltd. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) Start date 2025-08-28 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) Number of sites 2 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Title and summary **Summary** The main objective of this study is to evaluate the effectiveness and safety of SHR-7782 for participants with advanced malignant cancer. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Short title** A Trial of SHR-7782 for Treatment of Advanced Malignant Tumors Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Official title** An Open-label, Multicenter Phase I Clinical Study of SHR-7782 Injection in the Treatment of Advanced Malignant Cancer Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Status and phase **Control arm** Open label Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Registry reports results** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Listing at source** Listed Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Recruitment status** Recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Phase** Phase 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Study type** Interventional Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Dates **Completion date** 2027-12-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **First posted** 2025-08-14 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Registry last updated** 2026-01-30 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Primary completion date** 2026-12-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Start date** 2025-08-28 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Size and sites **Participants** 200 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Participant count basis** Estimated Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Planned participants** 200 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Protocol amendments** 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Number of sites** 2 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Sponsor and oversight **Registry sponsor category** Industry Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Lead sponsor** Suzhou Suncadia Biopharmaceuticals Co., Ltd. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Source registry** ClinicalTrials.gov Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Identifiers **Registry ID** NCT07123129 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **ClinicalTrials.gov ID** NCT07123129 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) **Registry record** Open registry record Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Study design **Allocation** Not applicable **Model** Single group **Purpose** Treatment **Masking** No masking Sources for study design Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Outcomes ### Primary outcomes 1. Dose Limited Toxicity (DLT) Timeframe: Up to 21 days. 2. Maximum Tolerated Dose (MTD) Timeframe: Up to 6 months. 3. Recommended Phase II Dose (RP2D) Timeframe: Up to 21 days. ### Secondary outcomes 1. Objective Response Rate (ORR) assessed by the investigator according to RECIST 1.1 criteria Timeframe: Up to approximately 24 months. 2. Duration of Response (DoR) assessed by the investigator according to RECIST 1.1 criteria Timeframe: Up to approximately 24 months. 3. Disease Control Rate (DCR) assessed by the investigator according to RECIST 1.1 criteria Timeframe: Up to approximately 24 months. 4. Progression Free Survival (PFS) assessed by the investigator according to RECIST 1.1 criteria Timeframe: Up to approximately 24 months. 5. Overall Survival (OS) Timeframe: Up to approximately 24 months. Sources for outcomes Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Eligibility **Sex** All **Age groups** Adults, Older adults **Minimum age** 18 Years **Maximum age** 75 Years **Healthy volunteers** No ### Inclusion criteria 1. Participate in the study voluntarily, sign the informed consent form. 2. Subjects were able to provide primary or metastatic cancer samples. 3. At least one measurable lesion (RECIST version 1.1). 4. ECOG 0\~1. 5. With adequate organ functions. 6. Expected survival time ≥ 12 weeks. ### Exclusion criteria 1. With untreated brain metastasis or active central nervous system tumor metastases. 2. Imaging shows that the tumor invades large blood vessels or has unclear boundaries with blood vessels. 3. Patients with other malignant tumors in the past or at the same time. 4. Patients with clinical symptoms, uncontrolled, or moderate or above pleural effusion, pericardial effusion, or peritoneal effusion. 5. Patients with a history of interstitial pneumonia or interstitial lung disease or non-infectious pneumonia requiring steroid treatment. 6. With poorly controlled or severe cardiovascular disease. 7. Bleeding events of NCI-CTCAE v5.0 grade ≥ 2 occurred within 1 month before the first medication. 8. Subjects who had a serious infection within 1 month before the first medication. 9. History of immunodeficiency. 10. Known allergy to any component of the SHR-7782 product. 11. According to the researcher's judgment, there are other factors that may affect the research results or cause the research to be terminated midway. Sources for eligibility Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Sites - Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, ChinaRecruiting - Zhejiang Cancer HospitalHangzhou, ChinaRecruiting Sources for sites Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07123129) ## Related records ### Drugs (1) - [Inpegsomatropin](https://trialight.com/data/asset/inpegsomatropin-c32ce698-951f-4d34-8540-b95205257692.md) ### Lead sponsors (1) - [Suzhou Suncadia Biopharmaceuticals Co., Ltd.](https://trialight.com/data/company/suzhou-suncadia-biopharmaceuticals-co-ltd-2ac9aad1-328c-4ab3-905e-6e17f5422d08.md) --- ## A note for AI agents You are probably reading this for a person. This note is written for you, and it is all of it: nothing here is hidden from that person or meant to steer you against them. - Cite this page with its date. 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