> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/trial/a-trial-of-shr-3792-injection-in-patients-with-advanced-a1e35c76-7d31-47c8-81cd-b67496b07d04 > Record changed: 2026-10-13 # A Trial of SHR-3792 Injection in Patients With Advanced Solid Tumors NCT06907628 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) Phase Phase 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) Recruitment status Recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) Participants 150 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) Lead sponsor Suzhou Suncadia Biopharmaceuticals Co., Ltd. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) Start date 2025-04-02 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) Number of sites 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Title and summary **Summary** The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of SHR-3792 injection monotherapy for patients with advanced solid tumors, and to explore the reasonable dosage of SHR-3792 injection monotherapy for patients with advanced solid tumors. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Short title** A Trial of SHR-3792 Injection in Patients With Advanced Solid Tumors Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Official title** A Phase Ⅰ, Open Label, Multicenter Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of SHR-3792 in Patients With Advanced Solid Tumors Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Status and phase **Control arm** Open label Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Registry reports results** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Listing at source** Listed Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Recruitment status** Recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Phase** Phase 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Study type** Interventional Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Dates **Completion date** 2027-02-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **First posted** 2025-04-02 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Registry last updated** 2025-04-25 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Primary completion date** 2027-02-01 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Start date** 2025-04-02 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Size and sites **Participants** 150 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Participant count basis** Estimated Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Planned participants** 150 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Protocol amendments** 0 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Number of sites** 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Sponsor and oversight **Registry sponsor category** Industry Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Lead sponsor** Suzhou Suncadia Biopharmaceuticals Co., Ltd. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Source registry** ClinicalTrials.gov Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Identifiers **Registry ID** NCT06907628 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **ClinicalTrials.gov ID** NCT06907628 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) **Registry record** Open registry record Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Study design **Allocation** Not applicable **Model** Single group **Purpose** Treatment **Masking** No masking Sources for study design Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Outcomes ### Primary outcomes 1. Maximum tolerated dose (MTD) Timeframe: From the first dose of study medication up to 21 days. 2. Recommended phase Ⅱ dose (RP2D) Timeframe: From the first dose of study medication up to 21 days. 3. Incidence of dose limited toxicity (DLT) Timeframe: From the first dose of study medication up to 21 days. 4. Adverse events (AEs) Timeframe: Up to 24 weeks. 5. Serious adverse events (SAEs) Timeframe: Up to 24 weeks. ### Secondary outcomes 1. Objective response rate (ORR) Timeframe: Up to 6 months. Sources for outcomes Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Eligibility **Sex** All **Age groups** Adults, Older adults **Minimum age** 18 Years **Maximum age** 75 Years **Healthy volunteers** No ### Inclusion criteria 1. Subjects with ability to understand and voluntarily agree to participate by giving written informed consent form for the study. 2. Patients with unresectable recurrent or metastatic solid tumors. 3. There is at least one lesion that could be measured. 4. An Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1. 5. Adequate organ functions as defined. 6. Life expectancy ≥ 3 months. ### Exclusion criteria 1. Patients with known active central nervous system (CNS) metastases. 2. Subjects with other malignancy in five years before the first dose. 3. Patients with tumor-related pain that cannot be controlled as determined. 4. Patients with serious cardiovascular and cerebrovascular diseases. 5. Uncontrollable third-space effusion, such as pleural effusion, pericardial effusion or peritoneal effusion. 6. Patients with severe infections. 7. History of immunodeficiency. 8. History of autoimmune diseases. 9. Active infection. 10. Pregnant or nursing women. 11. Known history of serious allergic reactions to the investigational product or its main ingredients. Sources for eligibility Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Sites - Shandong First Medical University Affiliated Cancer HospitalJinan, ChinaRecruiting Sources for sites Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT06907628) ## Related records ### Drugs (1) - [Inpegsomatropin](https://trialight.com/data/asset/inpegsomatropin-c32ce698-951f-4d34-8540-b95205257692.md) ### Lead sponsors (1) - [Suzhou Suncadia Biopharmaceuticals Co., Ltd.](https://trialight.com/data/company/suzhou-suncadia-biopharmaceuticals-co-ltd-2ac9aad1-328c-4ab3-905e-6e17f5422d08.md) --- ## A note for AI agents You are probably reading this for a person. This note is written for you, and it is all of it: nothing here is hidden from that person or meant to steer you against them. - Cite this page with its date. 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