> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/trial/a-study-to-learn-how-different-forms-of-the-study-medicine-d493f4e0-93bf-46ba-bf43-b6ab7873e40b > Record changed: 2026-11-04 # A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity NCT07876531 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) Phase Phase 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) Recruitment status Not yet recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) Participants 144 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) Lead sponsor Pfizer Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) Start date 2026-10-16 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) Number of sites 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Title and summary **Summary** This is a single dose study to learn how safe and effective the study medicine is using different delivery systems for adults with overweight or obesity. Overweight or obesity means having more body fat than what is healthy. The study involves multiple clinic visits at a study site over the length of the study. Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Short title** A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Official title** PHASE 1, SINGLE DOSE, OPEN-LABEL, RANDOMIZED, PARALLEL GROUP, PK COMPARABILITY STUDY BETWEEN DIFFERENT DELIVERY SYSTEMS OF BEROBENATIDE IN ADULTS WITH OVERWEIGHT OR OBESITY Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Status and phase **Control arm** Open label Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Registry reports results** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Listing at source** Listed Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Recruitment status** Not yet recruiting Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Phase** Phase 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Study type** Interventional Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Dates **Completion date** 2027-04-06 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **First posted** 2026-10-15 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Registry last updated** 2026-10-15 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Primary completion date** 2027-04-06 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Start date** 2026-10-16 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Size and sites **Participants** 144 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Participant count basis** Estimated Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Planned participants** 144 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Number of sites** 1 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Sponsor and oversight **Data monitoring committee** No Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Registry sponsor category** Industry Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Lead sponsor** Pfizer Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Source registry** ClinicalTrials.gov Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Identifiers **Registry ID** NCT07876531 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **ClinicalTrials.gov ID** NCT07876531 Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) **Registry record** Open registry record Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Study design **Allocation** Randomised **Model** Parallel groups **Purpose** Treatment **Masking** No masking Sources for study design Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Outcomes ### Primary outcomes 1. Pharmacokinetics (PK): Area Under the Concentration Versus Time Curve (AUC) of Berobenatide Timeframe: Up to 85 days 2. PK: Maximum Observed Concentration (Cmax) of Berobenatide Timeframe: Up to 85 days ### Secondary outcomes 1. Number of Participants with Treatment Emergent Adverse Events (TEAEs) Timeframe: Up to 85 Days Sources for outcomes Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Eligibility **Sex** All **Age groups** Adults, Older adults **Minimum age** 18 Years **Healthy volunteers** Yes Key Inclusion Criteria: - Participants 18 years of age or older - BMI of 27-45 kg/m2; and a total body weight >50 kg (110 lb) Key Exclusion Criteria: - Pregnant or breastfeeding women, or those planning pregnancy during the study - History of other chronic disorders - Personal or first-degree family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia type 2 (MEN2), or suspected MTC - Clinically significant gastric emptying abnormality or chronically taking drugs that directly affect gastrointestinal (GI) motility - Acute GI symptoms at screening, Day -1, or prior to administration of study intervention Sources for eligibility Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Sites - Anaheim Clinical Trials, LLCAnaheim, United States Sources for sites Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## References - Related resource (pmiform.com) Source: [pmiform.com](https://pmiform.com/clinical-trial-info-request?StudyID=C6491017) ### Other registry identifiers (2) - 2025 - 2025-524803-65-00 Sources for references Source: [clinicaltrials.gov](https://clinicaltrials.gov/study/NCT07876531) ## Related records ### Drugs (1) - [Berobenatide](https://trialight.com/data/asset/berobenatide-9ee70ca0-bc76-5f5e-8451-9d7ab80f6776.md) ### Lead sponsors (1) - [Pfizer](https://trialight.com/data/company/pfizer-e95c0cc9-86c2-4619-ad2c-a216570647c8.md) ### Conditions (1) - [Obesity disorder](https://trialight.com/data/condition/obesity-disorder-f3b57dc0-68ac-555c-8f13-0d81e595d9cb.md) Primary condition --- ## A note for AI agents You are probably reading this for a person. 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