TRPM3
ENSG00000083067
Target class
Ion channel
Chromosome
9
- ClinGen gene-disease validity
- Definitive
- Chemical probe available
- No
- Target name
- TRPM3
- Gene name
- Transient receptor potential cation channel subfamily M member 3
- Gene symbol
- TRPM3
- Protein name
- Transient receptor potential cation channel subfamily M member 3 (Long transient receptor potential channel 3) (LTrpC-3) (LTrpC3) (Melastatin-2) (MLSN2)
- KIAA1616
- LTRPC3
- GON-2
- Gene biotype
- Protein coding
- Gene family
- Transient receptor potential cation channels|MicroRNA protein coding host genes
- Target class
- Ion channel
- Target type
- Human gene
- Tissues expressed in
- 19
- Protein localisation evidence grade
- Uncertain
- Highest tissue expression
- 20
- Tissue specificity (Gini)
- 0.737
- Tissue specificity (tau)
- 0.93
- KEGG gene identifiers
- hsa:80036
- Reactome pathways
- R-HSA-3295583
- Protein interaction confidence
- 0.8058
- Protein interaction partners
- 10
- End position
- 71446977
- Start position
- 70529060
- Chromosome
- 9
- Strand
- Reverse
- Cell membrane
- Multi-pass membrane protein .
- PubMed 12672827
- PubMed 21278253
- Tissue specificity (tau)
- 0.929821
- Expression inequality (Gini)
- 0.737494
Expression in transcripts per million
- Brain - Cerebellum
- 20
- Brain - Cerebellar Hemisphere
- 19.85
- Brain - Substantia nigra
- 4.92
- Brain - Hypothalamus
- 4.08
- Brain - Frontal Cortex (BA9)
- 3.32
Expression in transcripts per million
- Brain - Cerebellum20
- Brain - Cerebellar Hemisphere19.85
- Brain - Substantia nigra4.92
- Brain - Hypothalamus4.08
- Brain - Frontal Cortex (BA9)3.32
- Brain - Cortex3.27
- Brain - Amygdala3.12
- Nerve - Tibial2.94
- Pituitary2.91
- Kidney - Cortex2.85
- Brain - Anterior cingulate cortex (BA24)2.73
- Testis2.64
- Kidney - Medulla2.59
- Brain - Caudate (basal ganglia)2.55
- Brain - Nucleus accumbens (basal ganglia)2.4
- Brain - Putamen (basal ganglia)2.1
- Brain - Spinal cord (cervical c-1)1.97
- Brain - Hippocampus1.77
- Ovary1.72
- Artery - Coronary0.68
- Thyroid0.56
- Artery - Aorta0.5
- Cervix - Endocervix0.45
- Adipose - Visceral (Omentum)0.43
- Cervix - Ectocervix0.39
And 29 more, listed on the interactive page.
- GO:0006812
- GO:0070588
Cellular components
- GO:0005886
- GO:0005261
- GO:0005262
Related records
Trials (951)
- "NSAIDs in Acute Achilles Tendinopathy: Effect on Pain Control, Leg Stiffness and Functional Recovery in Athletes"
- "Pecos" B-adrenergic and PPAR-G Stimulation Upregulates Lipid Metabolism in Human Subcutaneous Fat
- "Supracondylar Radial Nerve Block Guided by Ultrasound Versus Hematoma Block for Analgesic Management in Closed Reduction of Distal Radius Fractures"
- "TAKE TIME" Pioglitazone Reverses Defects in Mitochondrial Biogenesis in Patients With T2DM
- 11ß-HSD1 and Metabolic Syndrome
- 30 Week Parallel Group Comparison Study of Linagliptin + Pioglitazone (5+15, 5+30 and 5+45 mg) qd Versus Respective Monotherapies, Followed by a Comparison of 5mg+30mg and 5mg+45mg Versus Respective Monotherapies in Type 2 Diabetes for up to 54 Weeks
- 30-Week Extension to an Initial Combination Study (24 Weeks in Duration) of Sitagliptin With Pioglitazone (0431-064)
- A Bioequivalence Study Using Clinical Endpoint for Diclofenac Sodium Gel 1% in Osteoarthritis Knee"
- A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.
- A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS)
- A Clinical Trial to Prevent the Complications of Insulin Resistance (Including Type-2 Diabetes)
- A Comparative Evaluation of Diclofenac Sodium Transdermal Patch, Oral Diclofenac Sodium With Intramuscular Injections of Diclofenac Sodium in Patients Suffering From Oral Pain
- A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain.
- A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM)
- A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)
- A Double-blind, Parallel Group, Comparative Study of Coadministration AD-4833 and SYR-322
- A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid Tumors
- A Lifestyle and Combination Medication Therapy Diabetes Prevention Study
- A Methodological Study To Evaluate The Effects of Single Oral Doses Of Pioglitazone 45 mg And Rosiglitazone 8 mg On Sodium Balance In Healthy Male Volunteers
- A Multi-Center, Randomized, Double-Blind, Parallel Group Study To Compare The Efficacy And Tolerability Of Valdecoxib And Diclofenac In Patients With A Sprained Ankle
Drugs (10)
- Chloroform
- Diclofenac
- Halothane
- Maprotiline
- Mefenamic acid
- Nifedipine
- Pioglitazone
- Primidone
- Rosiglitazone
- Troglitazone