TAS2R46
ENSG00000226761
Target class
GPCR
Chromosome
12
- Chemical probe available
- No
- Other names
- T2R54
- Target name
- TAS2R46
- Gene name
- Taste 2 receptor member 46
- Gene symbol
- TAS2R46
- Protein name
- Taste receptor type 2 member 46 (T2R46) (Taste receptor type 2 member 54) (T2R54)
- Gene biotype
- Protein coding
- Gene family
- Taste 2 receptors
- Target class
- GPCR
- Target type
- Human gene
- Tissues expressed in
- 0
- Highest tissue expression
- 0.3
- Tissue specificity (Gini)
- 0.441
- Tissue specificity (tau)
- 0.703
- KEGG gene identifiers
- hsa:259292
- Protein interaction confidence
- 0.84725
- Protein interaction partners
- 8
- R-HSA-418594
- R-HSA-420499
- R-HSA-9717207
- End position
- 11062294
- Start position
- 11061365
- Chromosome
- 12
- Strand
- Reverse
- Membrane
- Multi-pass membrane protein . Cell projection, cilium membrane . Note=In airway epithelial cells, localizes to motile cilia.
Publication evidence
- PubMed 19628819
- Tissue specificity (tau)
- 0.703145
- Expression inequality (Gini)
- 0.441124
Expression in transcripts per million
- Brain - Cerebellum
- 0.3
- Brain - Cerebellar Hemisphere
- 0.26
- Ovary
- 0.26
- Cervix - Ectocervix
- 0.24
- Bladder
- 0.22
Expression in transcripts per million
- Brain - Cerebellum0.3
- Brain - Cerebellar Hemisphere0.26
- Ovary0.26
- Cervix - Ectocervix0.24
- Bladder0.22
- Testis0.21
- Nerve - Tibial0.18
- Uterus0.17
- Pituitary0.17
- Thyroid0.15
- Cells - EBV-transformed lymphocytes0.13
- Lung0.13
- Fallopian Tube0.13
- Adipose - Visceral (Omentum)0.13
- Cells - Cultured fibroblasts0.12
- Vagina0.12
- Prostate0.12
- Spleen0.11
- Artery - Aorta0.11
- Colon - Sigmoid0.11
- Skin - Not Sun Exposed (Suprapubic)0.1
- Artery - Coronary0.1
- Esophagus - Gastroesophageal Junction0.1
- Artery - Tibial0.1
- Skin - Sun Exposed (Lower leg)0.1
And 29 more, listed on the interactive page.
Biological processes
- GO:0001580
- GO:0005886
- GO:0016020
Molecular functions
- GO:0033038
Related records
Trials (292)
- A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice
- A Ph2, Colchicine For Inflammatory Carotid Injury And Disease Evolution After Radiotherapy
- A Pharmacokinetic Study of Colchicine With an Oral Contraceptive
- A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment
- A Phase III Trial of HMPL-004 in Patients With Mild to Moderate Active Ulcerative Colitis
- A Pilot Study for PK/PD Parameter of Colchicine in Chronic Kidney Disease Patient.
- A Randomized Multicenter Study for Isolated Skin Vasculitis
- A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis
- A Study of SSGJ-613 in Gout Participants Initiating Urate-Lowering Treatment
- A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.
- A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study)
- A Study of the Efficacy of Genakumab in Prevention of Acute Flares in Gout Patients Initiating Urate-lowering TherapyUrate-lowering (GenSci048-202)
- ACT-GLOBAL Adaptive Platform Trial for Stroke
- Adding Colchicine to Tocilizumab in Patients With Severe COVID-19 Pneumonia.
- Adjunctive Therapy of Andrographolid Sulfonatein Community Acquired Pneumonia
- Adjuvant Use Of Colchicine With The Standard Therapy In Moderate And Severe Corona Virus Disease-19 Infection
- Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)
- An Assessment of Chronic Synovial-Based Inflammation and Its Role With Serum Urate Levels.
- Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trial
- Anti-Inflammatory and Anti-Fibrotic Drugs in Post COVID-19 Pulmonary Fibrosis
Drugs (5)
- Andrographolide
- Colchicine
- Denatonium
- Strychnine
- Taurolithocholic acid