TAS2R38
ENSG00000257138
Target class
GPCR
Chromosome
7
- Chemical probe available
- No
- Other names
- T2R61
- Target name
- TAS2R38
- Gene name
- Taste 2 receptor member 38
- Gene symbol
- TAS2R38
- Previous gene symbols
- PTC
- Protein name
- Taste receptor type 2 member 38 (T2R38) (PTC bitter taste receptor) (Taste receptor type 2 member 61) (T2R61)
- Gene biotype
- Protein coding
- Gene family
- Taste 2 receptors
- Target class
- GPCR
- Target type
- Human gene
- Tissues expressed in
- 0
- Highest tissue expression
- 0.16
- Tissue specificity (Gini)
- 0.955
- Tissue specificity (tau)
- 0.982
- KEGG gene identifiers
- hsa:5726
- Protein interaction confidence
- 0.882429
- Protein interaction partners
- 7
- R-HSA-418594
- R-HSA-420499
- R-HSA-9717207
- End position
- 141973773
- Start position
- 141972631
- Chromosome
- 7
- Strand
- Reverse
- Membrane
- Multi-pass membrane protein.
- Tissue specificity (tau)
- 0.982311
- Expression inequality (Gini)
- 0.955197
Expression in transcripts per million
- Small Intestine - Terminal Ileum
- 0.16
- Testis
- 0.1
- Pancreas
- 0.03
- Colon - Transverse
- 0.02
- Artery - Aorta
- 0
Expression in transcripts per million
- Small Intestine - Terminal Ileum0.16
- Testis0.1
- Pancreas0.03
- Colon - Transverse0.02
- Artery - Aorta0
- Cervix - Ectocervix0
- Lung0
- Breast - Mammary Tissue0
- Brain - Anterior cingulate cortex (BA24)0
- Brain - Nucleus accumbens (basal ganglia)0
- Skin - Not Sun Exposed (Suprapubic)0
- Adrenal Gland0
- Brain - Frontal Cortex (BA9)0
- Colon - Sigmoid0
- Ovary0
- Cells - EBV-transformed lymphocytes0
- Cervix - Endocervix0
- Brain - Substantia nigra0
- Brain - Amygdala0
- Nerve - Tibial0
- Esophagus - Mucosa0
- Fallopian Tube0
- Brain - Hippocampus0
- Cells - Cultured fibroblasts0
- Minor Salivary Gland0
And 29 more, listed on the interactive page.
Biological processes
- GO:0001580
- GO:0005886
- GO:0016020
Molecular functions
- GO:0033038
Related records
Trials (98)
- 10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors
- A Clinical Follow-up Study on Drug Therapy for Graves' Disease Patients in China
- A Clinical Study of Hyperthyroidism in Children
- A Clinical Study of MK-8527 in Healthy Participants (MK-8527-021)
- A Conservative vs an Ablative Approach for Treatment of Hyperthyroidism in Patients With Graves' Orbitopathy
- A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.
- A Phase 1 Study to Evaluate the Effect of the Organic Anion Transporter Inhibitor Probenecid on the Pharmacokinetics of JNJ-64041575 in Healthy Adults
- A Relative Bioavailability Study With a Novel PanCytoVir™ Oral Suspension (100 mg/ml)
- A Study in Healthy People to Test How 2 Different Formulations of BI 690517 Are Taken up in the Body and How Probenecid Influences the Amount of BI 690517 in the Blood
- A Study of Baricitinib and Probenecid in Healthy Participants
- A Study of Cidofovir in HIV-Infected Children With Cytomegalovirus (CMV) Disease
- A Study to Assess Pharmacokinetics of PF-04965842 and Its Metabolites and Effect of Probenecid in Healthy Participants
- A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics and the Effect of Probenecid on Povorcitinib Pharmacokinetics When Administered Orally to Healthy Adult Participants
- A Study to Assess the Effects of Multiple-Dose Probenecid on the Multiple-Dose Pharmacokinetics of Canagliflozin in Healthy Volunteers
- A Study to Assess the Effects of Probenecid on the Pharmacokinetics of Mirdametinib and Its Metabolites in Healthy Participants
- A Study to Evaluate the Drug-drug Interactions (DDIs) of DBPR108 With Warfarin Sodium, Digoxin, Probenecid in Healthy Subjects
- A Study to Evaluate the Efficacy of PanCytoVir™ for the Treatment of Non-Hospitalized Patients With COVID-19 Infection
- A Study to Evaluate the Use of Cidofovir (an Experimental Drug) for the Treatment of Progressive Multifocal Leukoencephalopathy (PML) in AIDS Patients
- A Study to Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060
- A Trial Investigating the Effect of Probenecid and Ciclosporin on the Concentrations of SNAC in Healthy Subjects
Drugs (3)
- Methimazole
- Probenecid
- Propylthiouracil