> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/target/tas2r31-46698e44-da34-513b-802c-ef6da2c61bfc > Record changed: 2026-11-04 # TAS2R31 ENSG00000256436 Target class GPCR Chromosome 12 ## Druggability **Chemical probe available** No ## Names **Target name** TAS2R31 **Gene name** Taste 2 receptor member 31 **Gene symbol** TAS2R31 **Previous gene symbols** - TAS2R44 **Protein name** Taste receptor type 2 member 31 (T2R31) (Taste receptor type 2 member 44) (T2R44) (Taste receptor type 2 member 53) (T2R53) ### Other names (2) - T2R31 - T2R53 ## Classification **Gene biotype** Protein coding **Gene family** Taste 2 receptors **Target class** GPCR **Target type** Human gene ## Expression and localisation **Tissues expressed in** 8 **Highest tissue expression** 1.92 **Tissue specificity (Gini)** 0.404 **Tissue specificity (tau)** 0.715 ## Pathways and interactions **KEGG gene identifiers** - hsa:259290 **Protein interaction confidence** 0.7642 **Protein interaction partners** 5 ### Reactome pathways (3) - R-HSA-418594 - R-HSA-420499 - R-HSA-9717207 ## Genomic location **End position** 11031407 **Start position** 11030387 **Chromosome** 12 **Strand** Reverse ## Identifiers **Ensembl gene ID** ENSG00000256436 **HGNC ID** HGNC:19113 Source: [www.genenames.org](https://www.genenames.org/data/gene-symbol-report/#!/hgnc%5Fid/HGNC:19113) **NCBI Gene ID** 259290 **UniProt ID** P59538 ## Cellular location - Membrane - Multi-pass membrane protein. ## Tissue expression **Tissue specificity (tau)** 0.714721 **Expression inequality (Gini)** 0.403704 ### Highest expression Expression in transcripts per million **Ovary** 1.92 **Nerve - Tibial** 1.79 **Testis** 1.63 **Uterus** 1.28 **Pituitary** 1.24 ### All tissues (54) Expression in transcripts per million - Ovary1.92 - Nerve - Tibial1.79 - Testis1.63 - Uterus1.28 - Pituitary1.24 - Cells - EBV-transformed lymphocytes1.2 - Cervix - Endocervix1.16 - Fallopian Tube1.13 - Cervix - Ectocervix0.97 - Brain - Cerebellum0.96 - Cells - Cultured fibroblasts0.83 - Thyroid0.78 - Adipose - Subcutaneous0.74 - Lung0.72 - Artery - Tibial0.71 - Breast - Mammary Tissue0.71 - Brain - Cerebellar Hemisphere0.69 - Vagina0.69 - Prostate0.68 - Esophagus - Gastroesophageal Junction0.61 - Artery - Aorta0.6 - Bladder0.59 - Artery - Coronary0.57 - Esophagus - Muscularis0.54 - Colon - Sigmoid0.54 And 29 more, listed on the interactive page. ## Biological functions ### Biological processes - GO:0001580 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0001580) ### Cellular components (2) - GO:0005886 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0005886) - GO:0016020 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0016020) ### Molecular functions - GO:0033038 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0033038) ## Related records ### Trials (117) - A Multi-center, Randomized, Double-blind Phase III Clinical Trial to Assess and Compare to the Efficacy and Safety of Lafutidine, Famotidine and Omeprazole-referenced in Korean Erosive Esophagitis Patients - A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986263 in Healthy Participants - A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects - A Phase I/II Study of Intraperitoneal Paclitaxel in Patients With Metastatic Appendiceal Adenocarcinoma - A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive Cytology - A Phase II Trial of Neoadjuvant Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) With Chemoradiation - A Relative Bioavailability Study of 20 mg Famotidine Tablets Under Fasting Condition - A Relative Bioavailability Study of 20 mg Famotidine Tablets Under Fed Condition - [A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, and Drug-Drug Interaction Study of NX-5948 in Healthy Volunteers](https://trialight.com/data/trial/a-single-and-multiple-ascending-doses-relative-e765be29-f034-4382-84c2-075c49a7d226.md) - A Study Assessing the Drug Levels, Drug Effects, and Safety of BMS-986322 in Healthy Participants - A Study Comparing the Effects of Famotidine Pretreatment and of Food on the Relative Bioavailability of BMS-986165 in Healthy Volunteers - A Study Evaluating Relative Bioavailability of an Oral Suspension of Abrocitinib and Effect of an Acid Reducing Agent on the Bioavailability of Abrocitinib and Assessing the Taste of Abrocitinib Oral Formulations. - A Study in Healthy Male Subjects to Investigate the Effect of Famotidine and Efavirenz on the Way the Body Takes up, Distributes, and Gets Rid of Daridorexant. - A Study in Healthy Male Subjects to Understand How Savolitinib Behaves Inside the Body (Pharmacokinetics) When Administered Alone and in Combination With Famotidine - A Study to Assess the Bioequivalence of Famotidine/Antacid Combination Tablets Compared to Famotidine/Antacid EZ Chew Tablets (0208C-145)(COMPLETED) - A Study to Assess the Effect of Famotidine on the Drug Levels of Afimetoran in Healthy Participants - A Study to Assess the Effect of Itraconazole, Rifampin, and Acid-Reducing Agents on INCB161734 Pharmacokinetics When Administered Orally in Healthy Participants - A Study to Assess the Effects of Acid-Reducing Agent(s) on JNJ-64417184 in Healthy Participants - A Study to Assess the Effects of Itraconazole, Food, and pH on the Drug Levels of BMS-986368 in Healthy Participants - A Study to Determine the Effect of Famotidine on the Drug Levels of BMS-986256 in Healthy Participants ### Drugs (4) - Acesulfame - Cyclamic acid - [Famotidine](https://trialight.com/data/asset/famotidine-5721dbb9-1373-4622-a660-e27ebf480acc.md) - Saccharin --- ## A note for AI agents You are probably reading this for a person. 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