> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/target/tas2r3-0510463a-8e15-531b-8b74-613fe404a396 > Record changed: 2026-11-04 # TAS2R3 ENSG00000127362 Target class GPCR Chromosome 7 ## Druggability **Chemical probe available** No ## Names **Other names** - T2R3 **Target name** TAS2R3 **Gene name** Taste 2 receptor member 3 **Gene symbol** TAS2R3 **Protein name** Taste receptor type 2 member 3 (T2R3) ## Classification **Gene biotype** Protein coding **Gene family** Taste 2 receptors **Target class** GPCR **Target type** Human gene ## Expression and localisation **Tissues expressed in** 0 **Highest tissue expression** 0.77 **Tissue specificity (Gini)** 0.458 **Tissue specificity (tau)** 0.822 ## Pathways and interactions **KEGG gene identifiers** - hsa:50831 **Protein interaction confidence** 0.85175 **Protein interaction partners** 4 ### Reactome pathways (3) - R-HSA-418594 - R-HSA-420499 - R-HSA-9717207 ## Genomic location **End position** 141765197 **Start position** 141764097 **Chromosome** 7 **Strand** Forward ## Identifiers **Ensembl gene ID** ENSG00000127362 **HGNC ID** HGNC:14910 Source: [www.genenames.org](https://www.genenames.org/data/gene-symbol-report/#!/hgnc%5Fid/HGNC:14910) **NCBI Gene ID** 50831 **UniProt ID** Q9NYW6 ## Cellular location - Membrane - Multi-pass membrane protein. ## Tissue expression **Tissue specificity (tau)** 0.821612 **Expression inequality (Gini)** 0.458454 ### Highest expression Expression in transcripts per million **Brain - Cerebellum** 0.77 **Nerve - Tibial** 0.43 **Ovary** 0.4 **Brain - Cerebellar Hemisphere** 0.35 **Skin - Not Sun Exposed (Suprapubic)** 0.31 ### All tissues (54) Expression in transcripts per million - Brain - Cerebellum0.77 - Nerve - Tibial0.43 - Ovary0.4 - Brain - Cerebellar Hemisphere0.35 - Skin - Not Sun Exposed (Suprapubic)0.31 - Skin - Sun Exposed (Lower leg)0.3 - Cervix - Ectocervix0.3 - Uterus0.3 - Fallopian Tube0.29 - Cervix - Endocervix0.28 - Vagina0.24 - Cells - EBV-transformed lymphocytes0.23 - Thyroid0.23 - Minor Salivary Gland0.22 - Cells - Cultured fibroblasts0.21 - Small Intestine - Terminal Ileum0.19 - Esophagus - Gastroesophageal Junction0.17 - Bladder0.16 - Breast - Mammary Tissue0.16 - Pituitary0.14 - Testis0.14 - Esophagus - Muscularis0.14 - Colon - Sigmoid0.13 - Adipose - Subcutaneous0.12 - Kidney - Medulla0.11 And 29 more, listed on the interactive page. ## Biological functions ### Biological processes - GO:0001580 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0001580) ### Cellular components (2) - GO:0005886 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0005886) - GO:0016020 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0016020) ### Molecular functions (2) - GO:0008527 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0008527) - GO:0033038 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0033038) ## Related records ### Trials (132) - "Pharmacoepidemiological Evaluation of Autophagy Inhibition in Treatment of HCV Patients Resistant to Standard Therapy. Pilot Study" - A Comparative Study of Artekin With Standard Malarial Treatment Regimes in Afghanistan - A Pharmacokinetics, Safety and Efficacy Study of Tafenoquine (TQ) in Pediatric Subjects With Plasmodium Vivax (P. Vivax) Malaria - A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects - A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine - A Phase 2 Randomized, Double-blind Trial Evaluating the Effects of Chloroquine in Breast Cancer - A Randomized Controlled Trial for Intermittent Preventive Treatment in Pregnancy With Fansidar in Solomon Islands - A Study of Subcutaneous Tocilizumab as Monotherapy and/or in Combination With Non-Biologic Disease Modifying Anti-Rheumatic Drugs (DMARDs) in Participants With Rheumatoid Arthritis - A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh - A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria - Acceptability and Cost Effectiveness of Home Based Management of Fever: Different Strategies - ACT vs CQ With Tafenoquine for P. Vivax Mono-infection - Adjuvant Effect of Chloroquine on Gemcitabine - An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older - Antimalarial Drug Resistance in Mali - Antimalarial Drug Susceptibility and Molecular Characterization of Plasmodium Vivax Isolates in Vietnam - Artemether-lumefantrine vs Chloroquine for Uncomplicated P. Vivax Malaria in Malaysia - Artesunate Plus Sulfadoxine-Pyrimethamine Versus Chloroquine for Vivax Malaria - Assessing a Risk Model for G6PD Deficiency - Atheroma Reduction With Chloroquine in Patients With the Metabolic Syndrome (ARCH-MS) ### Drugs (1) - [Chloroquine](https://trialight.com/data/asset/chloroquine-60719e05-c0d4-438d-9681-2c553d6d6e4d.md) --- ## A note for AI agents You are probably reading this for a person. 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