> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/target/tas2r2-4e61f7ed-481d-5616-bbb2-0df6799d2fd5
> Record changed: 2026-11-04

# TAS2R2

ENSG00000203523

Chromosome

7

## Druggability

**Chemical probe available**

No

## Names

**Target name**

TAS2R2

**Gene name**

Taste 2 receptor member 2 (gene/pseudogene)

**Gene symbol**

TAS2R2

**Previous gene symbols**

- TAS2R2P

**Protein name**

Taste receptor type 2 member 2 (Bitter taste receptor T2R2)

### Other names (2)

- T2R02
- T2R2

## Classification

**Gene biotype**

Processed pseudogene

**Gene family**

Taste 2 receptors

**Target type**

Human gene

## Expression and localisation

**Tissues expressed in**

1

**Highest tissue expression**

1.51

**Tissue specificity (Gini)**

0.967

**Tissue specificity (tau)**

0.992

## Genomic location

**End position**

12492004

**Start position**

12491095

**Chromosome**

7

**Strand**

Forward

## Identifiers

**Ensembl gene ID**

ENSG00000203523

**HGNC ID**

HGNC:20615

Source: [www.genenames.org](https://www.genenames.org/data/gene-symbol-report/#!/hgnc%5Fid/HGNC:20615)

**NCBI Gene ID**

338396

**UniProt ID**

Q50KZ9

## Cellular location

- Cell membrane
- Multi-pass membrane protein .

### Publication evidence

- PubMed 28333344  
Source: [pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/28333344/)

## Tissue expression

**Tissue specificity (tau)**

0.992003

**Expression inequality (Gini)**

0.967183

### Highest expression

Expression in transcripts per million

**Testis**

1.51

**Kidney - Medulla**

0.45

**Kidney - Cortex**

0.19

**Skin - Sun Exposed (Lower leg)**

0

**Brain - Frontal Cortex (BA9)**

0

### All tissues (54)

Expression in transcripts per million

- Testis1.51
- Kidney - Medulla0.45
- Kidney - Cortex0.19
- Skin - Sun Exposed (Lower leg)0
- Brain - Frontal Cortex (BA9)0
- Lung0
- Brain - Cortex0
- Colon - Sigmoid0
- Heart - Atrial Appendage0
- Prostate0
- Brain - Cerebellar Hemisphere0
- Liver0
- Esophagus - Muscularis0
- Small Intestine - Terminal Ileum0
- Brain - Caudate (basal ganglia)0
- Uterus0
- Ovary0
- Colon - Transverse0
- Fallopian Tube0
- Brain - Spinal cord (cervical c-1)0
- Minor Salivary Gland0
- Adrenal Gland0
- Esophagus - Gastroesophageal Junction0
- Breast - Mammary Tissue0
- Brain - Hypothalamus0

And 29 more, listed on the interactive page.

## Biological functions

### Cellular components

- GO:0005886  
Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0005886)

### Molecular functions

- GO:0033038  
Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0033038)

## Related records

### Trials (274)

- "Clinical Trials to Enhance Elders' Oral Health" ("TEETH")
- \[11C\]Yohimbine PET Study of alpha2-AR
- 0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
- 0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis
- 2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
- A Clinical Study of Connective Tissue Graft and Enamel Matrix Derivative in the Treatment of Intrabony Periodontal Defects
- A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in Newborns
- A Comparison of Mouth Rinse Containing Alcohol-free Chlorhexidine With a Cetylpyridinium Chloride in Periodontal Diseases
- A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
- A Randomized Clinical Trial to Prevent Recurrent CA-MRSA Infection
- A Two-week Crossover Evaluation of Two Hand Antiseptic Products on Skin Condition in Healthy Human Subjects
- Active Oxygen Gel vs Chlorhexidine Gel in Stage II Grade B Periodontitis
- Alcoholic Chlorhexidine Compared to Povidone Iodine to Limit Perineural Catheter Colonisation
- Aloe Vera and Chlorhexidine Against Traumatic Oral Ulcers
- Animal-Assisted Visitation Program Chlorhexidine Trial
- Anti-inflammatory and Anti-plaque Efficacies of Mouth Rinse Containing Hyaluronic Acid and Hydrogen Peroxide
- Antibacterial Effect and Substantivity of a New Chlorhexidine and Cymenol Gel on Oral Biofilm and Saliva
- Antibacterial Effect of Chlorhexidine Added to the Preventive Protocol in Adolescent Special Needs
- Antibacterial Effect of Guava Leaves Extract Mouthwash Compared to Chlorhexidine Mouthwash in High Caries Risk Patients
- Antibacterial Effect of Nano Silver Fluoride vs Chlorhexidine on Occlusal Carious Molars Treated With Partial Caries Removal Technique

### Drugs (3)

- [Chlorhexidine](https://trialight.com/data/asset/chlorhexidine-73810300-e838-4872-8cbd-4e84000f38de.md)
- Phenylbutazone
- Yohimbine

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