NR2C2
ENSG00000177463
Target class
Nuclear receptor
Chromosome
3
- Chemical probe available
- No
- Target name
- NR2C2
- Gene name
- Nuclear receptor subfamily 2 group C member 2
- Gene symbol
- NR2C2
- Previous gene symbols
- TR4
- Protein name
- Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor TAK1) (Orphan nuclear receptor TR4) (Testicular receptor 4)
- TAK1
- TR2R1
- hTAK1
- Gene biotype
- Protein coding
- Gene family
- Nuclear receptor subfamily 2 group C
- Target class
- Nuclear receptor
- Target type
- Human gene
- Tissues expressed in
- 54
- Protein localisation evidence grade
- Enhanced
- Highest tissue expression
- 42.83
- Tissue specificity (Gini)
- 0.278
- Tissue specificity (tau)
- 0.579
- KEGG gene identifiers
- hsa:7182
- R-HSA-383280
- R-HSA-9940951
- End position
- 15053600
- Start position
- 14947544
- Chromosome
- 3
- Strand
- Forward
- Nucleus .
- Nucleoplasm
- PubMed 10644740
- PubMed 15302918
- Tissue specificity (tau)
- 0.579492
- Expression inequality (Gini)
- 0.278288
Expression in transcripts per million
- Thyroid
- 42.83
- Brain - Cerebellum
- 37.19
- Brain - Cerebellar Hemisphere
- 37
- Uterus
- 33.1
- Ovary
- 32.75
Expression in transcripts per million
- Thyroid42.83
- Brain - Cerebellum37.19
- Brain - Cerebellar Hemisphere37
- Uterus33.1
- Ovary32.75
- Cervix - Endocervix29.89
- Fallopian Tube27.6
- Pituitary27.57
- Nerve - Tibial27.55
- Cervix - Ectocervix27.44
- Lung26.95
- Artery - Tibial25.38
- Colon - Sigmoid24.56
- Bladder23.62
- Small Intestine - Terminal Ileum23.2
- Esophagus - Gastroesophageal Junction22.66
- Esophagus - Muscularis22.34
- Prostate22.18
- Vagina22.18
- Testis21.63
- Artery - Aorta21.43
- Spleen21.32
- Artery - Coronary21.31
- Cells - Cultured fibroblasts21.19
- Cells - EBV-transformed lymphocytes20.8
And 29 more, listed on the interactive page.
- GO:0000122
- GO:0006355
- GO:0007399
- GO:0033209
- GO:0043123
- GO:0045944
- GO:0046330
Cellular components
- GO:0005654
- GO:0000977
- GO:0000978
- GO:0001228
- GO:0003700
- GO:0005515
- GO:0043565
- GO:1990837
Related records
Trials (219)
- "AIDA" Protocol (LAP 0493)
- 90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)
- A Clinical Study Evaluating the Efficacy and Safety of Retinoic Acid in Patients With 15q11-q13 Duplication Syndrome
- A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT Gel
- A Community Trial for Visceral Leishmaniasis (VL)
- A Comparative Study of Adapalene Gel,0.3% Versus Tretinoin Emollient Cream, 0.05% for the Treatment of Photoaging
- A Fixed Triple Combination Cream for Solar Lentigines Associated to Cryotherapy
- A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment
- A Single-arm Trial of Roxadustat Combined With Retinoic Acid in the Treatment of Refractory Low-risk MDS
- A Study Comparing Combination Clindamycin Phosphate/Tretinoin Gel Alone Versus With Benzoyl Peroxide Foaming Cloths for Facial Acne
- A Study Comparing Tretinoin Cream 0.025% and RETIN-A® Cream 0.025% in the Treatment of Acne Vulgaris
- A Study Comparing Tretinoin Gel Microsphere, 0.04% and RETIN-A MICRO ® Gel Microsphere, 0.04% in the Treatment of Acne Vulgaris
- A Study Comparing Tretinoin Gel Microsphere, 0.1% and RETIN-A MICRO ® Gel Microsphere, 0.1% in the Treatment of Acne Vulgaris
- A Study of All-Trans Retinoic Acid (ATRA) and Bryostatin in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)
- A Study of ATRA in the Treatment of ITP
- A Study of Bomedemstat (IMG-7289/MK-3543) With and Without ATRA, in Participants With Advanced Myeloid Malignancies (IMG-7289-CTP-101/MK-3543-001)
- A Study of Daratumumab With Pomalidomide, Dexamethasone, and All-Transretinoic Acid in Patients With Multiple Myeloma
- A Study of Different Use Regimens Using Two Acne Treatments
- A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products
- A Study to Determine the Safety and Efficacy of Atralin (Tretinoin 0.05%) Gel for the Treatment of Rosacea
Drugs (2)
- Retinol
- Tretinoin