MPC2
ENSG00000143158
Target class
Transporter
Chromosome
1
- Chemical probe available
- No
- Target name
- MPC2
- Gene name
- Mitochondrial pyruvate carrier 2
- Gene symbol
- MPC2
- Previous gene symbols
- BRP44
- Protein name
- Mitochondrial pyruvate carrier 2 (Brain protein 44)
- DKFZP564B167
- SLC54A2
- Gene biotype
- Protein coding
- Gene family
- Solute carrier family 54, mitochondrial pyruvate carriers
- Target class
- Transporter
- Target type
- Human gene
- Tissues expressed in
- 54
- Highest tissue expression
- 165.04
- Tissue specificity (Gini)
- 0.231
- Tissue specificity (tau)
- 0.754
- KEGG gene identifiers
- hsa:25874
- Reactome pathways
- R-HSA-70268
- Protein interaction confidence
- 0.9415
- Protein interaction partners
- 2
- End position
- 167937502
- Start position
- 167916675
- Chromosome
- 1
- Strand
- Reverse
- Mitochondrion inner membrane
- Multi-pass membrane protein .
- PubMed 22628558
- PubMed 26253029
- PubMed 29472561
- PubMed 40044865
- PubMed 40101766
- Tissue specificity (tau)
- 0.754221
- Expression inequality (Gini)
- 0.23114
Expression in transcripts per million
- Testis
- 165.04
- Liver
- 75.14
- Brain - Frontal Cortex (BA9)
- 73.33
- Kidney - Medulla
- 70.5
- Stomach
- 65.62
Expression in transcripts per million
- Testis165.04
- Liver75.14
- Brain - Frontal Cortex (BA9)73.33
- Kidney - Medulla70.5
- Stomach65.62
- Prostate63.14
- Pituitary60.99
- Brain - Cerebellar Hemisphere60.46
- Muscle - Skeletal53.6
- Kidney - Cortex53.45
- Heart - Left Ventricle52.68
- Adrenal Gland52.56
- Brain - Anterior cingulate cortex (BA24)52.33
- Brain - Cortex49
- Brain - Cerebellum48.05
- Cells - EBV-transformed lymphocytes46.87
- Esophagus - Muscularis46.39
- Heart - Atrial Appendage46.31
- Brain - Nucleus accumbens (basal ganglia)45.9
- Artery - Aorta45.86
- Colon - Transverse45.2
- Brain - Hypothalamus43.81
- Esophagus - Gastroesophageal Junction42.34
- Brain - Caudate (basal ganglia)40.37
- Artery - Coronary40.27
And 29 more, listed on the interactive page.
Biological processes
- GO:0006850
- GO:0005634
- GO:0005739
- GO:0005743
- GO:7770001
- GO:0005515
- GO:0042802
Related records
Trials (104)
- [18F]F-DOPA Imaging in Patients With Autonomic Failure
- A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department
- A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
- A Safety, Tolerability and Levodopa Pharmacokinetics Study of Repeated ND0612 in Parkinson's Disease Patients
- A Safety, Tolerability, and Pharmacokinetic Study of ND0612 Delivered as a Continuous Subcutaneous in Parkinson's Disease Patients
- A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)
- A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa
- A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis)
- An Extension Study of Entacapone in Patients With Parkinson's Disease With End-of-dose Wearing-off. This Study is Not Recruiting in the United States
- An Open Clinical Trial of the Safety and Efficacy of the Drug Fluorothiazinone, 300 Mg Tablets with the Participation of Adult Patients with Chronic Bacterial Cystitis"
- An Open-Label Feasibility/Pilot Study With [123I]-IBZM SPECT (DOPA-SYN)
- Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract
- Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries
- Augmenting Effects of L-DOPS With Carbidopa and Entacapone
- Basic and Clinical Studies of Levodopa/Carbidopa/Entacapone in the Treatment of Early Parkinson's Disease
- Behavioral and Physiological Effects of Cocaine in Cocaine-dependent Participants Treated With Levodopa in Combination With Carbidopa and Entacapone (LCE)
- Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers
- Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers
- Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone in Healthy Volunteers
- Bioequivalence Study of Carbidopa/Levodopa/Entacapone Combination vs. Carbidopa/Levodopa Combination Plus Entacapone Under Fasting Conditions in Healthy Volunteers
Drugs (4)
- Entacapone
- Lonidamine
- Nitrofurantoin
- Zaprinast