> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/target/mpc1l-51aba135-ca2f-52f6-83dd-f5f8f9968eb1 > Record changed: 2026-11-04 # MPC1L ENSG00000238205 Chromosome X ## Druggability **Chemical probe available** No ## Names **Other names** - SLC54A3 **Target name** MPC1L **Gene name** Mitochondrial pyruvate carrier 1 like **Gene symbol** MPC1L **Protein name** Mitochondrial pyruvate carrier 1-like protein ## Classification **Gene biotype** Protein coding **Gene family** Solute carrier family 54, mitochondrial pyruvate carriers **Target type** Human gene ## Expression and localisation **Tissues expressed in** 1 **Highest tissue expression** 35.37 **Tissue specificity (Gini)** 0.981 **Tissue specificity (tau)** 1 ## Pathways and interactions **KEGG gene identifiers** - hsa:347411 **Reactome pathways** - R-HSA-70268 **Protein interaction confidence** 0.884 **Protein interaction partners** 1 ## Genomic location **End position** 40624136 **Start position** 40623428 **Chromosome** X **Strand** Forward ## Identifiers **Ensembl gene ID** ENSG00000238205 **HGNC ID** HGNC:44205 Source: [www.genenames.org](https://www.genenames.org/data/gene-symbol-report/#!/hgnc%5Fid/HGNC:44205) **NCBI Gene ID** 347411 **UniProt ID** P0DKB6 ## Cellular location - Mitochondrion inner membrane - Multi-pass membrane protein . ### Publication evidence - PubMed 27317664 Source: [pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/27317664/) ## Tissue expression **Tissue specificity (tau)** 0.999952 **Expression inequality (Gini)** 0.981387 ### Highest expression Expression in transcripts per million **Testis** 35.37 **Brain - Cerebellar Hemisphere** 0.09 **Adipose - Subcutaneous** 0 **Prostate** 0 **Brain - Cerebellum** 0 ### All tissues (54) Expression in transcripts per million - Testis35.37 - Brain - Cerebellar Hemisphere0.09 - Adipose - Subcutaneous0 - Prostate0 - Brain - Cerebellum0 - Muscle - Skeletal0 - Kidney - Medulla0 - Fallopian Tube0 - Colon - Transverse0 - Lung0 - Brain - Cortex0 - Heart - Atrial Appendage0 - Cells - EBV-transformed lymphocytes0 - Nerve - Tibial0 - Brain - Hippocampus0 - Brain - Putamen (basal ganglia)0 - Ovary0 - Cells - Cultured fibroblasts0 - Brain - Frontal Cortex (BA9)0 - Artery - Aorta0 - Liver0 - Artery - Tibial0 - Bladder0 - Brain - Nucleus accumbens (basal ganglia)0 - Thyroid0 And 29 more, listed on the interactive page. ## Biological functions ### Biological processes - GO:0006850 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0006850) ### Cellular components - GO:0005743 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0005743) ### Molecular functions - GO:0005515 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0005515) ## Related records ### Trials (109) - \[18F\]F-DOPA Imaging in Patients With Autonomic Failure - 3-month Study of MSDC-0160 Effects on Brain Glucose Utilization, Cognition & Safety in Subjects With Alzheimer's Disease - A Pilot Comparison of Short-course Nitrofurantoin in Females With Uncomplicated Bacterial Cystitis in the Emergency Department - A Placebo Controlled Safety and Efficacy Study of MSDC-0160 in Type 2 Diabetes With Active Comparator - A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy \[PCNL\]) - A Safety, Tolerability and Levodopa Pharmacokinetics Study of Repeated ND0612 in Parkinson's Disease Patients - A Safety, Tolerability, and Pharmacokinetic Study of ND0612 Delivered as a Continuous Subcutaneous in Parkinson's Disease Patients - [A Study of MSDC-0602K to Assess Glycemic Control and Cardiovascular Outcomes in Patients With Pre-T2D or T2D and NAFLD/NASH](https://trialight.com/data/trial/a-study-of-msdc-0602k-to-assess-glycemic-control-and-8022e3d3-4d7c-4b80-9407-d0dec8455a90.md) - A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI) - A Study to Evaluate Fixed Dose Carbidopa/Levodopa/Entacapone Versus Immediate Release Carbidopa/Levodopa - A Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH - A Study to Investigate the Efficacy and Safety With Gepotidacin in Japanese Female Participants With Uncomplicated Urinary Tract Infection (Acute Cystitis) - An Extension Study of Entacapone in Patients With Parkinson's Disease With End-of-dose Wearing-off. This Study is Not Recruiting in the United States - An Open Clinical Trial of the Safety and Efficacy of the Drug Fluorothiazinone, 300 Mg Tablets with the Participation of Adult Patients with Chronic Bacterial Cystitis" - An Open-Label Feasibility/Pilot Study With \[123I\]-IBZM SPECT (DOPA-SYN) - Antibiotic Prophylaxis and Renal Damage In Congenital Abnormalities of the Kidney and Urinary Tract - Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries - Augmenting Effects of L-DOPS With Carbidopa and Entacapone - Basic and Clinical Studies of Levodopa/Carbidopa/Entacapone in the Treatment of Early Parkinson's Disease - Behavioral and Physiological Effects of Cocaine in Cocaine-dependent Participants Treated With Levodopa in Combination With Carbidopa and Entacapone (LCE) ### Drugs (5) - Entacapone - Lonidamine - [Mitoglitazone](https://trialight.com/data/asset/mitoglitazone-0c8bdda3-d7bd-4c10-b3bd-e0aeb98e082f.md) - [Nitrofurantoin](https://trialight.com/data/asset/nitrofurantoin-1409e75a-3142-41c2-80b4-5db81a22c2f6.md) - Zaprinast --- ## A note for AI agents You are probably reading this for a person. 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