KCNT1
ENSG00000107147
Target class
Unclassified protein
Chromosome
9
- ClinGen gene-disease validity
- Definitive
- Chemical probe available
- No
- Target name
- KCNT1
- Gene name
- Potassium sodium-activated channel subfamily T member 1
- Gene symbol
- KCNT1
- Protein name
- Potassium channel subfamily T member 1 (KCa4.1) (KNa1.1) (Sodium and chloride-activated ATP-sensitive potassium channel Slo2.2)
- KCa4.1
- KIAA1422
- SLACK
- Slo2.2
- Gene biotype
- Protein coding
- Gene family
- Potassium sodium-activated channel subfamily T
- Target class
- Unclassified protein
- Target type
- Human gene
- Tissues expressed in
- 18
- Protein localisation evidence grade
- Supported
- Highest tissue expression
- 94.67
- Tissue specificity (Gini)
- 0.829
- Tissue specificity (tau)
- 0.943
- KEGG gene identifiers
- hsa:57582
- Protein interaction confidence
- 0.749167
- Protein interaction partners
- 6
- End position
- 135795508
- Start position
- 135702185
- Chromosome
- 9
- Strand
- Forward
- Cell membrane
- Multi-pass membrane protein .
- Nucleoplasm
- Plasma membrane
Publication evidence
- PubMed 37494189
- Tissue specificity (tau)
- 0.942924
- Expression inequality (Gini)
- 0.829031
Expression in transcripts per million
- Brain - Cerebellum
- 94.67
- Brain - Cerebellar Hemisphere
- 80.08
- Brain - Cortex
- 44.09
- Brain - Frontal Cortex (BA9)
- 30.35
- Spleen
- 20.19
Expression in transcripts per million
- Brain - Cerebellum94.67
- Brain - Cerebellar Hemisphere80.08
- Brain - Cortex44.09
- Brain - Frontal Cortex (BA9)30.35
- Spleen20.19
- Brain - Anterior cingulate cortex (BA24)16.32
- Brain - Putamen (basal ganglia)13.56
- Brain - Caudate (basal ganglia)12.87
- Pituitary12.6
- Brain - Nucleus accumbens (basal ganglia)8.03
- Brain - Hypothalamus7.03
- Ovary7.01
- Muscle - Skeletal6.31
- Brain - Hippocampus5.45
- Brain - Amygdala5.23
- Testis2.54
- Brain - Substantia nigra1.34
- Brain - Spinal cord (cervical c-1)1.21
- Fallopian Tube0.8
- Artery - Coronary0.72
- Colon - Sigmoid0.67
- Heart - Left Ventricle0.65
- Lung0.63
- Adipose - Visceral (Omentum)0.58
- Uterus0.56
And 29 more, listed on the interactive page.
- GO:0051289
- GO:0071805
Cellular components
- GO:0005886
- GO:0005228
- GO:0005515
Related records
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- A Phase 1 Study Comparing AVP-786 With AVP-923
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- A Phase-1 Study to Assess the Pharmacokinetics, Safety and Tolerability of AVP-786 in Healthy Volunteers
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Drugs (6)
- Antrafenine
- Clofilium
- Clofilium phosphate
- Loxapine
- Niclosamide
- Quinidine