IL12RB1
ENSG00000096996
Target class
Membrane receptor
Chromosome
19
- Chemical probe available
- No
- Other names
- CD212
- Target name
- IL12RB1
- Gene name
- Interleukin 12 receptor subunit beta 1
- Gene symbol
- IL12RB1
- Previous gene symbols
- IL12RB
- Protein name
- Interleukin-12 receptor subunit beta-1 (IL-12 receptor subunit beta-1) (IL-12R subunit beta-1) (IL-12R-beta-1) (IL-12RB1) (IL-12 receptor beta component) (CD antigen CD212)
- Gene biotype
- Protein coding
- Gene family
- CD molecules|Fibronectin type III domain containing|Interleukin receptors
- Target class
- Membrane receptor
- Target type
- Human gene
- Tissues expressed in
- 11
- Protein localisation evidence grade
- Approved
- Highest tissue expression
- 17.52
- Tissue specificity (Gini)
- 0.673
- Tissue specificity (tau)
- 0.93
- KEGG gene identifiers
- hsa:3594
- Protein interaction confidence
- 0.82425
- Protein interaction partners
- 60
- R-HSA-9020591
- R-HSA-9020933
- End position
- 18098944
- Start position
- 18058995
- Chromosome
- 19
- Strand
- Reverse
- Membrane
- Single-pass type I membrane protein.
- Plasma membrane
- Tissue specificity (tau)
- 0.930333
- Expression inequality (Gini)
- 0.672508
Expression in transcripts per million
- Spleen
- 17.52
- Cells - EBV-transformed lymphocytes
- 16.55
- Whole Blood
- 9.76
- Small Intestine - Terminal Ileum
- 4.99
- Lung
- 4.63
Expression in transcripts per million
- Spleen17.52
- Cells - EBV-transformed lymphocytes16.55
- Whole Blood9.76
- Small Intestine - Terminal Ileum4.99
- Lung4.63
- Adipose - Visceral (Omentum)1.39
- Colon - Transverse1.29
- Fallopian Tube1.21
- Artery - Coronary1.1
- Artery - Aorta1.03
- Brain - Spinal cord (cervical c-1)1.03
- Nerve - Tibial0.99
- Adipose - Subcutaneous0.97
- Bladder0.95
- Cervix - Endocervix0.9
- Prostate0.86
- Minor Salivary Gland0.83
- Adrenal Gland0.78
- Brain - Nucleus accumbens (basal ganglia)0.75
- Kidney - Medulla0.74
- Breast - Mammary Tissue0.7
- Pituitary0.68
- Stomach0.67
- Thyroid0.66
- Testis0.62
And 29 more, listed on the interactive page.
- GO:0002230
- GO:0002827
- GO:0007165
- GO:0019221
- GO:0032729
- GO:0035722
- GO:0038155
- GO:0042104
- GO:0071346
- GO:0005886
- GO:0042022
- GO:0072536
- GO:0004896
- GO:0005143
- GO:0015026
- GO:0016517
- GO:0042019
- GO:0042020
Related records
Trials (4)
- A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
- A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
- A Study to Evaluate the Efficacy and Safety of Icotrokinra (JNJ-77242113) in Biologic-experienced and Biologic-naive Participants With Active Psoriatic Arthritis
- A Study to Evaluate the Efficacy and Safety of JNJ-77242113 (Icotrokinra) in Biologic-naïve Participants With Active Psoriatic Arthritis