> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/target/gpr33-8da458e0-6322-5e31-8827-bfee8866a7c0
> Record changed: 2026-11-04

# GPR33

ENSG00000214943

Chromosome

14

## Druggability

**Chemical probe available**

No

## Names

**Target name**

GPR33

**Gene name**

G protein-coupled receptor 33

**Gene symbol**

GPR33

**Protein name**

Probable G-protein coupled receptor 33

## Classification

**Gene biotype**

Protein coding

**Gene family**

G protein-coupled receptors, Class A orphans

**Target type**

Human gene

## Expression and localisation

**Tissues expressed in**

0

**Highest tissue expression**

0.02

**Tissue specificity (Gini)**

0.981

**Tissue specificity (tau)**

1

## Pathways and interactions

**KEGG gene identifiers**

- hsa:2856

## Genomic location

**End position**

31488039

**Start position**

31482875

**Chromosome**

14

**Strand**

Reverse

## Identifiers

**Ensembl gene ID**

ENSG00000214943

**HGNC ID**

HGNC:4489

Source: [www.genenames.org](https://www.genenames.org/data/gene-symbol-report/#!/hgnc%5Fid/HGNC:4489)

**NCBI Gene ID**

2856

**UniProt ID**

Q49SQ1

## Cellular location

- Cell membrane
- Multi-pass membrane protein.

## Tissue expression

**Tissue specificity (tau)**

1

**Expression inequality (Gini)**

0.981481

### Highest expression

Expression in transcripts per million

**Testis**

0.02

**Artery - Tibial**

0

**Muscle - Skeletal**

0

**Adipose - Subcutaneous**

0

**Brain - Anterior cingulate cortex (BA24)**

0

### All tissues (54)

Expression in transcripts per million

- Testis0.02
- Artery - Tibial0
- Muscle - Skeletal0
- Adipose - Subcutaneous0
- Brain - Anterior cingulate cortex (BA24)0
- Nerve - Tibial0
- Cervix - Ectocervix0
- Prostate0
- Skin - Sun Exposed (Lower leg)0
- Small Intestine - Terminal Ileum0
- Colon - Transverse0
- Brain - Putamen (basal ganglia)0
- Fallopian Tube0
- Bladder0
- Heart - Atrial Appendage0
- Colon - Sigmoid0
- Lung0
- Adipose - Visceral (Omentum)0
- Vagina0
- Brain - Caudate (basal ganglia)0
- Thyroid0
- Brain - Hippocampus0
- Adrenal Gland0
- Heart - Left Ventricle0
- Esophagus - Gastroesophageal Junction0

And 29 more, listed on the interactive page.

## Related records

### Trials (352)

- 05-001: Treatment of Acute Lymphoblastic Leukemia in Children
- 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer
- 506U78 in Treating Patients With Refractory Hematologic Cancer
- A Comparative Clinical Trial Evaluating the Effect and Safety of Tacrolimus Versus Hydrocortisone
- A Comparative Study Between Two Formulations of the Ciprofloxacin Hydrochloride + Hydrocortisone Otic Suspension
- A Comparative Study of Glucocorticoids Efficacy in Acute Respiratory Distress Syndrome
- A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer
- A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe Asthmatics
- A Pilot Trial of Pediatric Liver Transplantation Without Steroids
- A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids Plus Azathioprine for Acute Severe Colitis
- A Study Comparing LEO 80190 Ointment With Hydrocortisone Ointment, Both Applied Once Daily in the Treatment of Psoriasis Vulgaris on the Face and Intertriginous Areas
- A Study in Adults With Untreated Acute Lymphoblastic Leukemia
- A Study of Chronocort® Versus Cortef ® in Healthy Adult Male Subjects
- A Study of Infacort® Versus Cortef® in Healthy Adult Male and Female Subjects
- A Study of Opevesostat (MK-568)4 in Japanese Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-005)
- A Study of Opevesostat (MK-5684) in China Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (MK-5684-001)
- [A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)](https://trialight.com/data/trial/a-study-of-opevesostat-mk-5684-versus-alternative-next-40ece519-da89-4905-86a7-0c1a844d57e4.md)
- A Study of Standard of Care Drugs With or Without Ivermectin for Daraxonrasib-Induced Skin Toxicity in People With Pancreatic Cancer
- A Study of the Efficacy, Safety and Tolerability of Chronocort in Treating CAH
- A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

### Drugs (1)

- [Hydrocortisone](https://trialight.com/data/asset/hydrocortisone-2a0db2d4-4a67-4db0-851f-091bd6b99fdb.md)

---

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