GLRA2
ENSG00000101958
Target class
Ion channel
Chromosome
X
- Chemical probe available
- No
- Target name
- GLRA2
- Gene name
- Glycine receptor alpha 2
- Gene symbol
- GLRA2
- Previous gene symbols
- GLR
- Protein name
- Glycine receptor subunit alpha-2
- Gene biotype
- Protein coding
- Gene family
- Glycine receptors
- Target class
- Ion channel
- Target type
- Human gene
- Tissues expressed in
- 8
- Protein localisation evidence grade
- Approved
- Highest tissue expression
- 16.43
- Tissue specificity (Gini)
- 0.886
- Tissue specificity (tau)
- 0.955
- KEGG gene identifiers
- hsa:2742
- Reactome pathways
- R-HSA-112314
- Protein interaction confidence
- 0.781
- Protein interaction partners
- 2
- End position
- 14731812
- Start position
- 14529298
- Chromosome
- X
- Strand
- Forward
- Postsynaptic cell membrane
- Multi-pass membrane protein . Synapse . Cell membrane
- Multi-pass membrane protein . Cell projection .
- Plasma membrane
- PubMed 15302677
- PubMed 16144831
- PubMed 2155780
- PubMed 23895467
- PubMed 25445488
- PubMed 26370147
- Tissue specificity (tau)
- 0.955006
- Expression inequality (Gini)
- 0.885629
Expression in transcripts per million
- Brain - Cerebellar Hemisphere
- 16.43
- Brain - Cerebellum
- 13.41
- Brain - Hypothalamus
- 8.12
- Brain - Nucleus accumbens (basal ganglia)
- 3.42
- Brain - Anterior cingulate cortex (BA24)
- 2.98
Expression in transcripts per million
- Brain - Cerebellar Hemisphere16.43
- Brain - Cerebellum13.41
- Brain - Hypothalamus8.12
- Brain - Nucleus accumbens (basal ganglia)3.42
- Brain - Anterior cingulate cortex (BA24)2.98
- Brain - Amygdala2.71
- Brain - Frontal Cortex (BA9)2.42
- Brain - Cortex1.7
- Brain - Caudate (basal ganglia)0.81
- Brain - Putamen (basal ganglia)0.72
- Brain - Spinal cord (cervical c-1)0.51
- Brain - Substantia nigra0.5
- Brain - Hippocampus0.5
- Pituitary0.43
- Colon - Transverse0.23
- Colon - Sigmoid0.14
- Nerve - Tibial0.11
- Ovary0.09
- Small Intestine - Terminal Ileum0.07
- Testis0.07
- Fallopian Tube0.04
- Cervix - Endocervix0.04
- Kidney - Cortex0.03
- Cells - Cultured fibroblasts0.02
- Esophagus - Muscularis0.02
And 29 more, listed on the interactive page.
- GO:0007218
- GO:0034220
- GO:0071230
- GO:0071294
- GO:0071361
- GO:1902476
Cellular components
- GO:0005886
- GO:0016594
- GO:0016934
- GO:0022852
Related records
Trials (501)
- A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice
- A Laboratory Model of Increasing Delta-9-tetrahydrocannabinol (THC) Potency on Cigarette Smoking
- A Ph2, Colchicine For Inflammatory Carotid Injury And Disease Evolution After Radiotherapy
- A Pharmacokinetic Study of Colchicine With an Oral Contraceptive
- A Phase 4 Safety and Efficacy Study to Evaluate Lesinurad 200 mg in Participants With Gout and Renal Impairment
- A Phase I/II Study to Evaluate Single Agent and Combination Therapy With Megestrol Acetate and Dronabinol for the Treatment of HIV-Wasting Syndrome
- A Pilot Study for PK/PD Parameter of Colchicine in Chronic Kidney Disease Patient.
- A Pilot Study of Dronabinol for Adult Patients With Primary Gliomas
- A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surgery
- A Randomized Multicenter Study for Isolated Skin Vasculitis
- A RCT Comparing Dronabinol to a Placebo for Post-operative Pain in Total Joint Arthroplasty
- A Study Evaluating the Efficacy and Safety of Aprepitant in Autologous Hematopoietic Stem Cell Transplantation
- A Study of Cybis™ 10:25 THC:CBD Oil in Adults With Chronic Back/Neck Pain
- A Study of SSGJ-613 in Gout Participants Initiating Urate-Lowering Treatment
- A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.
- A Study Of Synthetic THC And Sleep
- A Study of the Abuse Potential of Dronabinol in Recreational Cannabinoid Users
- A Study of the Efficacy of Canakinumab in Prevention of Acute Flares in Chronic Gout Patients Initiating Allopurinol Therapy (Core Study) and a Long-term Study of the Efficacy and Safety of Canakinumab in Patients With Gout (Extension Study)
- A Study of the Efficacy of Genakumab in Prevention of Acute Flares in Gout Patients Initiating Urate-lowering TherapyUrate-lowering (GenSci048-202)
- A Study Testing the Safety and Effects of Single Doses of S1-221 in Healthy Volunteers
Drugs (5)
- Colchicine
- Dronabinol
- Onternabez
- Strychnine
- Tropisetron