> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/target/ctrc-7ecc1091-694b-554d-a425-ded8ed88cc3a > Record changed: 2026-11-04 # CTRC ENSG00000162438 Target class Enzyme Chromosome 1 ## Druggability **Chemical probe available** No ## Names **Target name** CTRC **Gene name** Chymotrypsin C **Gene symbol** CTRC **Protein name** Chymotrypsin-C (EC 3.4.21.2) (Caldecrin) ### Other names (2) - CLCR - ELA4 ## Classification **Gene biotype** Protein coding **Gene family** Chymotrypsins **Target class** Enzyme **Target type** Human gene ## Expression and localisation **Tissues expressed in** 1 **Highest tissue expression** 3,339.98 **Tissue specificity (Gini)** 0.978 **Tissue specificity (tau)** 1 ## Pathways and interactions **KEGG gene identifiers** - hsa:11330 **Reactome pathways** - R-HSA-9925561 **Protein interaction confidence** 0.807222 **Protein interaction partners** 9 ## Genomic location **End position** 15449242 **Start position** 15438442 **Chromosome** 1 **Strand** Forward ## Identifiers **Ensembl gene ID** ENSG00000162438 **HGNC ID** HGNC:2523 Source: [www.genenames.org](https://www.genenames.org/data/gene-symbol-report/#!/hgnc%5Fid/HGNC:2523) **NCBI Gene ID** 11330 **UniProt ID** Q99895 ## Tissue expression **Tissue specificity (tau)** 0.999906 **Expression inequality (Gini)** 0.978198 ### Highest expression Expression in transcripts per million **Pancreas** 3,339.98 **Spleen** 0.89 **Testis** 0.72 **Cervix - Ectocervix** 0.71 **Whole Blood** 0.69 ### All tissues (54) Expression in transcripts per million - Pancreas3,339.98 - Spleen0.89 - Testis0.72 - Cervix - Ectocervix0.71 - Whole Blood0.69 - Fallopian Tube0.67 - Brain - Cerebellum0.52 - Uterus0.52 - Prostate0.52 - Ovary0.48 - Vagina0.47 - Lung0.47 - Pituitary0.44 - Bladder0.43 - Small Intestine - Terminal Ileum0.41 - Esophagus - Mucosa0.39 - Brain - Cerebellar Hemisphere0.38 - Stomach0.38 - Thyroid0.38 - Cervix - Endocervix0.37 - Adrenal Gland0.35 - Adipose - Subcutaneous0.33 - Skin - Not Sun Exposed (Suprapubic)0.32 - Skin - Sun Exposed (Lower leg)0.32 - Artery - Aorta0.32 And 29 more, listed on the interactive page. ## Biological functions ### Biological processes (2) - GO:0006508 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0006508) - GO:0006874 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0006874) ### Molecular functions (2) - GO:0005515 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0005515) - GO:0008233 Source: [www.ebi.ac.uk](https://www.ebi.ac.uk/QuickGO/term/GO:0008233) ## Related records ### Trials (26) - A Study Evaluating Drug Drug Interaction Between Milvexian and Atorvastatin in Healthy Participants - A Study of JNJ-70033093 (BMS-986177) in Healthy Adult Participants - A Study of JNJ-70033093 (BMS-986177) in Healthy Chinese Adult Participants - A Study of JNJ-70033093 (BMS-986177) Versus Subcutaneous Enoxaparin in Participants Undergoing Elective Total Knee Replacement Surgery - A Study of JNJ-70033093 (Milvexian) in Healthy Adult Participants - A Study of JNJ-70033093 and Digoxin in Healthy Participants - A Study of JNJ-70033093 in Healthy Participants - A Study of Milvexian in Healthy Adult Females - [A Study of Milvexian in Participants After a Recent Acute Coronary Syndrome](https://trialight.com/data/trial/a-study-of-milvexian-in-participants-after-a-recent-acute-0b485d43-2b27-4d92-b8a0-1716a132b945.md) - [A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE](https://trialight.com/data/trial/a-study-of-milvexian-in-participants-after-an-acute-ischemic-ef73fb8c-7882-4291-a1aa-bb4cc7f9d2a3.md) - A Study of Milvexian Using an IV Microtracer With Additional Formulation and Food Effect Comparison in Healthy Participants - [A Study of Milvexian Versus Apixaban in Participants With Atrial Fibrillation](https://trialight.com/data/trial/a-study-of-milvexian-versus-apixaban-in-participants-with-e26ab0d2-647d-49a6-bf8b-cc799e52b193.md) - A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel - A Study to Assess Administration of an Oral Anti-thrombotic With Antiplatelet Therapy in Healthy Subjects - A Study to Assess the Reversal of the Anticoagulant Effects of Milvexian by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy Participants - A Study to Evaluate Safety of Single Doses of BMS-986177 in Patients With End Stage Renal Disease (ESRD) Treated With Hemodialysis - A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Pharmacokinetics of BMS-986177 in Healthy Subjects - A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics of BMS-986177 in Healthy Subjects - A Study to Evaluate the Safety and Pharmacokinetics of BMS-986177 in Participants With End-stage Renal Dysfunction on Chronic Stable Hemodialysis Treatment - An Investigational Study to Assess the Effect of BMS-986177 on Aspirin in Healthy Participants ### Drugs (1) - [Milvexian](https://trialight.com/data/asset/milvexian-339c16a0-10d4-46bb-9570-47b9050a80b1.md) --- ## A note for AI agents You are probably reading this for a person. 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