CETP
ENSG00000087237
Target class
Ion channel
Chromosome
16
Approved drugs
0
Clinical candidates (approved and in development)
6
- Approved drugs
- 0
- Clinical candidates (approved and in development)
- 6
- Chemical probe available
- Yes
- Other names
- BPIFF
- Target name
- CETP
- Gene name
- Cholesteryl ester transfer protein
- Gene symbol
- CETP
- Protein name
- Cholesteryl ester transfer protein (Lipid transfer protein I)
- Gene biotype
- Protein coding
- Gene family
- BPI fold containing
- Target class
- Ion channel
- Target type
- Human gene
- Tissues expressed in
- 14
- Highest tissue expression
- 34.97
- Tissue specificity (Gini)
- 0.708
- Tissue specificity (tau)
- 0.967
- KEGG gene identifiers
- hsa:1071
- Protein interaction confidence
- 0.853814
- Protein interaction partners
- 43
- R-HSA-8964041
- R-HSA-8964058
- R-HSA-9029569
- End position
- 56983845
- Start position
- 56961923
- Chromosome
- 16
- Strand
- Forward
- Secreted . Note=Secreted in plasma. .
- PubMed 24293641
- PubMed 3281933
- Tissue specificity (tau)
- 0.967098
- Expression inequality (Gini)
- 0.708299
Expression in transcripts per million
- Spleen
- 34.97
- Thyroid
- 7.14
- Adipose - Visceral (Omentum)
- 6.59
- Cells - EBV-transformed lymphocytes
- 4.95
- Pituitary
- 4.08
Expression in transcripts per million
- Spleen34.97
- Thyroid7.14
- Adipose - Visceral (Omentum)6.59
- Cells - EBV-transformed lymphocytes4.95
- Pituitary4.08
- Kidney - Medulla3.62
- Breast - Mammary Tissue3.03
- Adipose - Subcutaneous2.95
- Lung2.94
- Kidney - Cortex2.63
- Liver2.35
- Adrenal Gland2.11
- Whole Blood1.24
- Small Intestine - Terminal Ileum1.1
- Artery - Coronary0.97
- Testis0.66
- Prostate0.66
- Uterus0.65
- Cervix - Endocervix0.64
- Cervix - Ectocervix0.55
- Brain - Spinal cord (cervical c-1)0.51
- Brain - Caudate (basal ganglia)0.51
- Artery - Aorta0.5
- Skin - Sun Exposed (Lower leg)0.49
- Brain - Putamen (basal ganglia)0.49
And 29 more, listed on the interactive page.
- GO:0006641
- GO:0006869
- GO:0008203
- GO:0010745
- GO:0010874
- GO:0030301
- GO:0032376
- GO:0034197
- GO:0034372
- GO:0034374
- GO:0034375
- GO:0042632
- GO:0043691
- GO:0046470
- GO:0055088
- GO:0055091
- GO:0070328
- GO:2001140
- GO:0005576
- GO:0031982
- GO:0034364
- GO:0070062
- GO:0008289
- GO:0015485
- GO:0017129
- GO:0031210
- GO:0120014
- GO:0120020
Related records
Trials (109)
- A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
- A Clinical Trial Comparing Torcetrapib/Atorvastatin to Ezetimibe/Simvastatin In Subjects With A Cholesterol Disorder.
- A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol (A5091031).
- A Clinical Trial Comparing Torcetrapib/Atorvastatin To Simvastatin In Subjects With High Cholesterol.
- A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease
- A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy.
- A Drug-drug Interaction Study Evaluating the PK Effects of Obicetrapib on Atorvastatin and Rosuvastatin
- A Formulation Screening Study of Dalcetrapib and Atorvastatin in Healthy Volunteers
- A Long Term Extension of Study NC19453 Evaluating Safety and Efficacy of RO4607381
- A Preliminary Drug Drug Interaction Study With TA-8995
- A Study Assessing the Effect of RO4607381 on Vascular Function in Patients With Coronary Heart Disease (CHD) or CHD-Risk Equivalent Patients
- A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides
- A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart Disease
- A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)
- A Study of Dalcetrapib in Patients With Stable Coronary Heart Disease, With Coronary Heart Disease Risk Equivalents or at Elevated Risk for Cardiovascular Disease
- A Study of Different Particle Sizes of Evacetrapib in Healthy Participants
- A Study of Evacetrapib (LY2484595) and Warfarin in Healthy Participants
- A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia
- A Study of Evacetrapib (LY2484595) in Healthy Participants
- A Study of Evacetrapib (LY2484595) in Japanese Participants With Primary Hypercholesterolemia
Drugs (6)
- Anacetrapib Cholesteryl ester transfer protein inhibitor
- Dalcetrapib Cholesteryl ester transfer protein inhibitor
- Evacetrapib Cholesteryl ester transfer protein inhibitor
- Obicetrapib Cholesteryl ester transfer protein inhibitor
- Rocacetrapib Cholesteryl ester transfer protein inhibitor
- Torcetrapib Cholesteryl ester transfer protein inhibitor