CDH6
ENSG00000113361
Chromosome
5
- Chemical probe available
- No
- Target name
- CDH6
- Gene name
- Cadherin 6
- Gene symbol
- CDH6
- Protein name
- Cadherin-6 (Kidney cadherin) (K-cadherin)
- Gene biotype
- Protein coding
- Gene family
- Type II classical cadherins
- Target type
- Human gene
- Tissues expressed in
- 35
- Protein localisation evidence grade
- Supported
- Highest tissue expression
- 16.65
- Tissue specificity (Gini)
- 0.51
- Tissue specificity (tau)
- 0.862
- KEGG gene identifiers
- hsa:1004
- Reactome pathways
- R-HSA-418990
- Protein interaction confidence
- 0.7836
- Protein interaction partners
- 15
- End position
- 31329146
- Start position
- 31193686
- Chromosome
- 5
- Strand
- Forward
- Cell membrane
- Single-pass type I membrane protein.
- Cell Junctions
- Plasma membrane
- Tissue specificity (tau)
- 0.861658
- Expression inequality (Gini)
- 0.510233
Expression in transcripts per million
- Artery - Tibial
- 16.65
- Nerve - Tibial
- 10.44
- Kidney - Cortex
- 7.94
- Artery - Coronary
- 6.22
- Kidney - Medulla
- 5.7
Expression in transcripts per million
- Artery - Tibial16.65
- Nerve - Tibial10.44
- Kidney - Cortex7.94
- Artery - Coronary6.22
- Kidney - Medulla5.7
- Lung5.5
- Cervix - Ectocervix5.25
- Brain - Caudate (basal ganglia)4.75
- Adipose - Subcutaneous4.33
- Brain - Putamen (basal ganglia)3.92
- Adipose - Visceral (Omentum)3.86
- Fallopian Tube3.66
- Cervix - Endocervix3.61
- Thyroid3.25
- Uterus3.17
- Esophagus - Gastroesophageal Junction3.06
- Brain - Hypothalamus2.79
- Brain - Frontal Cortex (BA9)2.75
- Breast - Mammary Tissue2.73
- Bladder2.51
- Brain - Substantia nigra2.47
- Brain - Spinal cord (cervical c-1)2.44
- Brain - Anterior cingulate cortex (BA24)2.32
- Vagina2.3
- Brain - Cortex2.11
And 29 more, listed on the interactive page.
Biological processes
- GO:0007155
- GO:0005886
- GO:0030054
Related records
Trials (5)
- A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003).
- A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors
- A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)
- A Study of Raludotatug Deruxtecan (R-DXd) in People With Gastrointestinal Cancers (MK-5909-005)
- A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01)