CA6
ENSG00000131686
Target class
Enzyme
Chromosome
1
Approved drugs
1
Clinical candidates (approved and in development)
2
- Approved drugs
- 1
- Clinical candidates (approved and in development)
- 2
- Chemical probe available
- No
- Target name
- CA6
- Gene name
- Carbonic anhydrase 6
- Gene symbol
- CA6
- Protein name
- Carbonic anhydrase 6 (EC 4.2.1.1) (Carbonate dehydratase VI) (Carbonic anhydrase VI) (CA-VI) (Salivary carbonic anhydrase) (Secreted carbonic anhydrase)
- Gene biotype
- Protein coding
- Gene family
- Carbonic anhydrases
- Target class
- Enzyme
- Target type
- Human gene
- Tissues expressed in
- 2
- Highest tissue expression
- 21.36
- Tissue specificity (Gini)
- 0.965
- Tissue specificity (tau)
- 0.989
- KEGG gene identifiers
- hsa:765
- Reactome pathways
- R-HSA-1475029
- Protein interaction confidence
- 0.830167
- Protein interaction partners
- 6
- End position
- 8975092
- Start position
- 8945867
- Chromosome
- 1
- Strand
- Forward
- Secreted.
- Tissue specificity (tau)
- 0.989488
- Expression inequality (Gini)
- 0.964778
Expression in transcripts per million
- Skin - Sun Exposed (Lower leg)
- 21.36
- Skin - Not Sun Exposed (Suprapubic)
- 11.26
- Spleen
- 0.18
- Whole Blood
- 0.08
- Pituitary
- 0.08
Expression in transcripts per million
- Skin - Sun Exposed (Lower leg)21.36
- Skin - Not Sun Exposed (Suprapubic)11.26
- Spleen0.18
- Whole Blood0.08
- Pituitary0.08
- Minor Salivary Gland0.07
- Testis0.06
- Breast - Mammary Tissue0.03
- Brain - Hippocampus0.02
- Thyroid0.01
- Small Intestine - Terminal Ileum0.01
- Brain - Spinal cord (cervical c-1)0.01
- Brain - Substantia nigra0.01
- Lung0.01
- Adipose - Subcutaneous0.01
- Esophagus - Mucosa0.01
- Brain - Amygdala0.01
- Cells - EBV-transformed lymphocytes0.01
- Nerve - Tibial0.01
- Brain - Hypothalamus0.01
- Brain - Caudate (basal ganglia)0.01
- Stomach0
- Prostate0
- Brain - Cerebellar Hemisphere0
- Cervix - Ectocervix0
And 29 more, listed on the interactive page.
Biological processes
- GO:0001580
- GO:0005576
- GO:0070062
Molecular functions
- GO:0004089
Related records
Trials (4)
- Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
- Efficacy, Safety and Tolerability of Sulthiame in Patients With Obstructive Sleep Apnea (OSA)
- Pharmacokinetics and Tolerability of Sulthiame
- Population Pharmacokinetics of Antiepileptic in Pediatrics
Drugs (2)
- Ethoxzolamide Carbonic anhydrase inhibitor
- Sulthiame Carbonic anhydrase inhibitor