CA5B
ENSG00000169239
Target class
Enzyme
Chromosome
X
Approved drugs
1
Clinical candidates (approved and in development)
2
- Approved drugs
- 1
- Clinical candidates (approved and in development)
- 2
- Chemical probe available
- No
- Target name
- CA5B
- Gene name
- Carbonic anhydrase 5B
- Gene symbol
- CA5B
- Protein name
- Carbonic anhydrase 5B, mitochondrial (EC 4.2.1.1) (Carbonate dehydratase VB) (Carbonic anhydrase VB) (CA-VB)
- Gene biotype
- Protein coding
- Gene family
- Carbonic anhydrases
- Target class
- Enzyme
- Target type
- Human gene
- Tissues expressed in
- 51
- Protein localisation evidence grade
- Supported
- Highest tissue expression
- 14.52
- Tissue specificity (Gini)
- 0.377
- Tissue specificity (tau)
- 0.708
- KEGG gene identifiers
- hsa:11238
- Reactome pathways
- R-HSA-1475029
- Protein interaction confidence
- 0.8045
- Protein interaction partners
- 2
- End position
- 15788411
- Start position
- 15688830
- Chromosome
- X
- Strand
- Forward
- Mitochondrion .
- Mitochondria
Publication evidence
- PubMed 10409679
- Tissue specificity (tau)
- 0.708223
- Expression inequality (Gini)
- 0.377416
Expression in transcripts per million
- Artery - Aorta
- 14.52
- Cervix - Ectocervix
- 14.17
- Testis
- 11.98
- Artery - Tibial
- 11.69
- Artery - Coronary
- 10.16
Expression in transcripts per million
- Artery - Aorta14.52
- Cervix - Ectocervix14.17
- Testis11.98
- Artery - Tibial11.69
- Artery - Coronary10.16
- Cervix - Endocervix9.82
- Ovary8.86
- Vagina7.23
- Nerve - Tibial7.2
- Uterus6.96
- Adipose - Subcutaneous6.53
- Breast - Mammary Tissue6.07
- Thyroid5.67
- Fallopian Tube5.58
- Skin - Sun Exposed (Lower leg)5.12
- Lung4.94
- Prostate4.58
- Minor Salivary Gland4.51
- Brain - Substantia nigra4.38
- Skin - Not Sun Exposed (Suprapubic)4.3
- Bladder4.21
- Adipose - Visceral (Omentum)3.77
- Cells - Cultured fibroblasts3.75
- Esophagus - Gastroesophageal Junction3.67
- Brain - Nucleus accumbens (basal ganglia)3.64
And 29 more, listed on the interactive page.
- GO:0005739
- GO:0005759
- GO:0004089
- GO:0005515
Related records
Trials (4)
- Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
- Efficacy, Safety and Tolerability of Sulthiame in Patients With Obstructive Sleep Apnea (OSA)
- Pharmacokinetics and Tolerability of Sulthiame
- Population Pharmacokinetics of Antiepileptic in Pediatrics
Drugs (2)
- Ethoxzolamide Carbonic anhydrase inhibitor
- Sulthiame Carbonic anhydrase inhibitor