CA3
ENSG00000164879
Target class
Enzyme
Chromosome
8
Approved drugs
1
Clinical candidates (approved and in development)
2
- Approved drugs
- 1
- Clinical candidates (approved and in development)
- 2
- Chemical probe available
- No
- Target name
- CA3
- Gene name
- Carbonic anhydrase 3
- Gene symbol
- CA3
- Protein name
- Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III)
- Car3
- CAIII
- Gene biotype
- Protein coding
- Gene family
- Carbonic anhydrases
- Target class
- Enzyme
- Target type
- Human gene
- Tissues expressed in
- 47
- Highest tissue expression
- 1,382.94
- Tissue specificity (Gini)
- 0.914
- Tissue specificity (tau)
- 0.997
- KEGG gene identifiers
- hsa:761
- Reactome pathways
- R-HSA-1475029
- Protein interaction confidence
- 0.774
- Protein interaction partners
- 4
- End position
- 85449040
- Start position
- 85373436
- Chromosome
- 8
- Strand
- Forward
- Cytoplasm .
Publication evidence
- PubMed 18618712
- Tissue specificity (tau)
- 0.99725
- Expression inequality (Gini)
- 0.914051
Expression in transcripts per million
- Muscle - Skeletal
- 1,382.94
- Lung
- 28.53
- Cervix - Endocervix
- 11.05
- Adipose - Visceral (Omentum)
- 9.89
- Fallopian Tube
- 8.7
Expression in transcripts per million
- Muscle - Skeletal1,382.94
- Lung28.53
- Cervix - Endocervix11.05
- Adipose - Visceral (Omentum)9.89
- Fallopian Tube8.7
- Minor Salivary Gland8.64
- Uterus8.47
- Cervix - Ectocervix6.81
- Artery - Coronary6.39
- Vagina6.2
- Pituitary5.88
- Small Intestine - Terminal Ileum5.64
- Kidney - Medulla5.54
- Breast - Mammary Tissue5.14
- Thyroid5
- Skin - Not Sun Exposed (Suprapubic)4.77
- Heart - Atrial Appendage4.66
- Prostate4.49
- Skin - Sun Exposed (Lower leg)4.45
- Nerve - Tibial3.81
- Testis3.71
- Brain - Cerebellar Hemisphere3.6
- Stomach3.4
- Brain - Cerebellum3.24
- Artery - Aorta3.08
And 29 more, listed on the interactive page.
- GO:0005737
- GO:0005829
- GO:0004089
- GO:0005515
Related records
Trials (4)
- Effect of Sulthiame on EEG in Childhood Epilepsy Syndromes
- Efficacy, Safety and Tolerability of Sulthiame in Patients With Obstructive Sleep Apnea (OSA)
- Pharmacokinetics and Tolerability of Sulthiame
- Population Pharmacokinetics of Antiepileptic in Pediatrics
Drugs (2)
- Ethoxzolamide Carbonic anhydrase inhibitor
- Sulthiame Carbonic anhydrase inhibitor