ADGRG3
ENSG00000182885
Target class
GPCR
Chromosome
16
- Chemical probe available
- No
- Target name
- ADGRG3
- Gene name
- Adhesion G protein-coupled receptor G3
- Gene symbol
- ADGRG3
- Previous gene symbols
- GPR97
- Protein name
- Adhesion G protein-coupled receptor G3 (G-protein coupled receptor 97) [Cleaved into: Adhesion G-protein coupled receptor G3, N-terminal fragment (ADGRG3 N-terminal fragment); Adhesion G-protein coupled receptor G3, C-terminal fragment (ADGRG3 C-terminal fragment)]
- Pb99
- PGR26
- Gene biotype
- Protein coding
- Gene family
- Adhesion G protein-coupled receptors, subfamily G
- Target class
- GPCR
- Target type
- Human gene
- Tissues expressed in
- 28
- Highest tissue expression
- 492.04
- Tissue specificity (Gini)
- 0.908
- Tissue specificity (tau)
- 0.992
- KEGG gene identifiers
- hsa:222487
- Reactome pathways
- R-HSA-6798695
- Protein interaction confidence
- 0.835667
- Protein interaction partners
- 3
- End position
- 57689378
- Start position
- 57668277
- Chromosome
- 16
- Strand
- Forward
- Cell membrane
- Multi-pass membrane protein .
- PubMed 22575658
- PubMed 33408414
- Tissue specificity (tau)
- 0.992359
- Expression inequality (Gini)
- 0.908009
Expression in transcripts per million
- Whole Blood
- 492.04
- Spleen
- 76.57
- Lung
- 28.3
- Adipose - Visceral (Omentum)
- 10.73
- Thyroid
- 9.98
Expression in transcripts per million
- Whole Blood492.04
- Spleen76.57
- Lung28.3
- Adipose - Visceral (Omentum)10.73
- Thyroid9.98
- Fallopian Tube8.54
- Small Intestine - Terminal Ileum6.61
- Cervix - Ectocervix5.64
- Breast - Mammary Tissue4.06
- Colon - Sigmoid3.3
- Esophagus - Muscularis2.89
- Colon - Transverse2.8
- Adipose - Subcutaneous2.79
- Esophagus - Gastroesophageal Junction2.76
- Vagina2.48
- Bladder2.36
- Cervix - Endocervix2.26
- Skin - Sun Exposed (Lower leg)1.85
- Liver1.76
- Esophagus - Mucosa1.68
- Uterus1.56
- Stomach1.53
- Skin - Not Sun Exposed (Suprapubic)1.51
- Kidney - Cortex1.46
- Prostate1.4
And 29 more, listed on the interactive page.
- GO:0007186
- GO:0007193
- GO:0030334
- GO:0005886
- GO:0016020
- GO:0035579
- GO:0004930
- GO:0005515
Related records
Trials (111)
- (CARE Network Trial - Treating Children to Prevent Exacerbations of Asthma (TREXA)
- 7 Day Study of Mast Cell Inhibitor, R926112, in Patients With Symptomatic Seasonal Allergic Rhinitis
- A 12-week Safety and Efficacy Study of Beclomethasone Dipropionate (80 and 160 mcg/Day) Delivered Via Breath-Actuated Inhaler (BAI) in Patients >=12 Years Old With Persistent Asthma
- A Dose Ranging Study of Delayed Release Beclomethasone for Prevention of Acute Enteritis in Patients With Rectal Cancer
- A Randomized Double Blind Placebo Controlled Study of the Effect of Swallowed Beclomethasone Dipropionate on Inflammatory Markers in Adult Patients With Eosinophilic Esophagitis
- A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants >=12 Years Old With Persistent Asthma
- A Safety and Efficacy Study of Beclomethasone Dipropionate Delivered Via Breath-Actuated Inhaler (BAI) or Metered-Dose Inhaler (MDI) in Participants Ages 4-11 Years Old With Persistent Asthma
- A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD
- A Study Comparing the Effects of Trimbow to Fostair in COPD
- A Study in Patients With Chronic Obstructive Pulmonary Disease
- A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled Corticosteroid
- A Study to Evaluate the Acute Bronchodilator Effect of CHF1535 NEXThaler
- A Study to Investigate the Pharmacokinetics and Safety of Beclomethasone Dipropionate Administered by Breath-Actuated Inhaler and Metered-Dose Inhaler in Healthy Adults
- A Study to Investigate the Pharmacokinetics, Safety and Tolerability of CHF 5993 pMDI in Subjects With Renal Impairment.
- Allergic Rhinitis Changes the Sinus Microbiome
- Assessment of Oxidative Stress Markers in the Upper and Lower Airways of Atopic Children Treated With Nebulized Beclomethasone
- Asthma Clinical Research Network (ACRN) Trial - Long-Acting Beta Agonist Response by Genotype (LARGE)
- Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC)
- Beclometasone Dipropionate and Formoterol Inhalation Aerosol for Asthma
- Beclomethasone Dipropionate HFA in Adult and Adolescent Subjects With Mild to Moderate Persistent Asthma