> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/waldenstrom-macroglobulinemia-63d0de52-623d-5c8e-8377-11dbc3feb969 > Record changed: 2026-10-13 # Waldenstrom macroglobulinemia Therapeutic area Metabolic Disease Rare disease Yes ## Definition and classification **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Waldenstrom macroglobulinemia **Therapeutic area** Metabolic Disease ### Alternative names (8) - Waldenstrom macroglobulinemia - Waldenstrom macroglobulinemia - Waldenstrom's macroglobulinemia - Waldenström Macroglobulinemia - Waldenström macroglobulinemia - Waldenstrom's macroglobulinaemia - Waldenstrom's syndrome - macroglobulinemia of Waldenstrom ## Clinical profile **Severity** Unknown ### Disease mechanisms (3) - Genetic - Hereditary - Inborn Error of Metabolism ### All therapeutic areas (4) - Hematology - Immunology - Metabolic Disease - Oncology ## Identifiers **MONDO ID** MONDO:0100280 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0100280) **Parent condition** MONDO:0000432 ## Related records ### Broader conditions (25) - [B-cell neoplasm](https://trialight.com/data/condition/b-cell-neoplasm-ffd0710d-7dbd-55bc-a4a5-3c1cf532bac2.md) - [B-cell non-Hodgkin lymphoma](https://trialight.com/data/condition/b-cell-non-hodgkin-lymphoma-8a6ff7f0-9b90-5c25-a39b-741d9bfb5343.md) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by developmental or physiological process - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - Hematologic disorder - [Hematopoietic and lymphoid cell neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9.md) - [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md) - Hereditary disease - Human disease - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Inborn errors of metabolism - Indolent B-cell non-Hodgkin lymphoma - Leukocyte disorder - Lymphoid hemopathy - Lymphoid neoplasm - [Lymphoma](https://trialight.com/data/condition/lymphoma-de4db685-7419-5e0e-b958-4591ffd69d43.md) ### Narrower conditions (2) - Macroglobulinemia, Waldenstrom, 1 - Macroglobulinemia, Waldenstrom, 2 ### Trials (524) - 12-O-Tetradecanoylphorbol-13-acetate in Treating Patients With Hematologic Cancer or Bone Marrow Disorder - 1630GCC: Zydelig Maintenance in B-Cell Non-Hodgkin's Lymphoma After Autologous Stem Cell Transplantation - 17-Dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in Treating Patients With an Advanced Solid Tumor or Lymphoma - 17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas - 17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer - 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis - 19(T2)28z1xx Chimeric Antigen Receptor (CAR) T Cells in People With B-Cell Cancers - 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma - 3'-Deoxy-3'-\[18F\] Fluorothymidine PET Imaging in Patients With Cancer - 506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment - 506U78 in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or T-cell Lymphoma - A Clinical Trial of BP1002 in Patients With Advanced Lymphoid Malignancies - A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies - A Long-term Extension Study of PCI-32765 (Ibrutinib) - A Phase 1 Dose Escalation Study of TAK-901 in Subjects With Advanced Hematologic Malignancies - A Phase 2 Clinical Trial to Evaluate Zanubrutinib Combined With BR (Bendamustine/Rituximab) Regimen in Subjects With Newly-diagnosed Waldenström's Macroglobulinemia - A Phase 2 Study to Evaluate the Safety and Efficacy of Pacritinib in Relapsed or Refractory Waldenström Macroglobulinemia - A Phase I Trial of DI-B4 in Patients With Advanced CD19 Positive Indolent B-cell Malignancies - A Phase II Clinical Study of Zanubrutinib Combined With Four Cycles of CD20 Monoclonal Antibody and Reduced-Dose Bendamustine in the Treatment of Untreated Waldenström Macroglobulinemia - A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan ### Approved drugs (2) - [Ibrutinib](https://trialight.com/data/asset/ibrutinib-0b3ac4fd-6e98-4847-a711-2f599e8bb93d.md) - [Zanubrutinib](https://trialight.com/data/asset/zanubrutinib-7763b1f8-43b7-49a8-8bc2-ca3940603ee6.md) ### Drugs in development (65) - Acalabrutinib Phase 2 - Agatolimod sodium Phase 1 - Alemtuzumab Phase 2 - Alvocidib hydrochloride Phase 1 - Antineoplaston A10 Phase 2 - APG-2575 Phase 1 - Bazlitoran Phase 1 - [Bendamustine](https://trialight.com/data/asset/bendamustine-07f7a21f-820a-4423-a534-0d6d0380b382.md) Phase 2 - BI-1206 Phase 1 - [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 2 - Bortezomib D-mannitol Phase 2 - [Carfilzomib](https://trialight.com/data/asset/carfilzomib-42f49602-1f34-4e14-b345-79d6fd69324f.md) Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3 - Cyclosporine Phase 3 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Phase 2 - Dasatinib anhydrous Phase 1 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3 - Edodekin alfa Phase 2 - Enzastaurin Phase 2 - Epratuzumab Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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