> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/vulvar-intraepithelial-neoplasia-64079781-2636-5ed9-a853-daae88cf66e8
> Record changed: 2026-10-13

# Vulvar intraepithelial neoplasia

Therapeutic area

Oncology

Rare disease

Yes

## Definition and classification

**Definition**

Intraepithelial neoplasia of the vulvar squamous epithelium. There is no evidence of invasion. This category includes vulvar high grade squamous intraepithelial lesion and vulvar intraepithelial neoplasia, differentiated type.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Vulvar intraepithelial neoplasia

**Therapeutic area**

Oncology

### Alternative names (9)

- vulvar intraepithelial neoplasia
- VIN
- intraepithelial neoplasia of the vulva
- intraepithelial neoplasia of vulva
- squamous vulvar intraepithelial neoplasia
- vulva intraepithelial neoplasia
- vulval intraepithelial neoplasia
- vulvar intraepithelial tumor
- vulvar intraepithelial tumour

## Clinical profile

**Severity**

Moderate

### All therapeutic areas (2)

- Oncology
- Reproductive Health

## Identifiers

**MONDO ID**

MONDO:0005198

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005198)

**Parent condition**

MONDO:0002195

## Related records

### Broader conditions (16)

- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md)
- Female reproductive system disorder
- Female reproductive system neoplasm
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Reproductive system disorder
- Reproductive system neoplasm
- Squamous cell neoplasm
- [Vulvar disease](https://trialight.com/data/condition/vulvar-disease-f913835c-1959-587d-9c26-5a7c0588d35d.md)
- [Vulvar neoplasm](https://trialight.com/data/condition/vulvar-neoplasm-d4e15333-0337-5005-9712-3420729bb7b7.md)
- Vulvar squamous neoplasm

### Narrower conditions (1)

- Low grade vulvar intraepithelial neoplasia

### Trials (20)

- A Bridging Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls
- Artesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)
- Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer
- Cavitronic Ultrasonic Surgical Aspiration (CUSA) Women's Health Study
- Early Detection of Vulval CAncer Through Self-Examination (EDuCATE): Intervention Study
- Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent（Type 16/18 ）Vaccine
- Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia
- Evaluation of VGX-3100 and Electroporation Alone or in Combination With Imiquimod for the Treatment of HPV-16 and/or HPV-18 Related Vulvar HSIL (Also Referred as: VIN 2 or VIN 3)
- Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls
- Immuno-persistence Study of a Recombinant Human Papillomavirus 16/18 Bivalent Vaccine in Preadolescent Girls (54m)
- InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
- Interest of the Confocal Microscope in the Diagnosis of Epidermoid Carcinoma of the Vulva and Their Precursors
- Lot Consistency Clinical Trial of of Recombinant HPV Bivalent Vaccine in 9 to14 Years Old Healthy Female
- [Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9](https://trialight.com/data/trial/phase-iii-study-comparing-the-immunogenicity-of-9-valent-hpv-338e3ab0-8b14-4db9-bd66-273ecb7fd7b1.md)
- Primary Imiquimod Treatment Versus Surgery for Vulvar Intraepithelial Neoplasia
- SR-T100 Gel Efficacy & Safety Study for Vulva Pre-cancerous Lesions & Cutaneous Condyloma
- The Durability of Protection and Immuno-persistence Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female
- The Durability of Protection Study of a Recombinant HPV 16/18 Bivalent Vaccine in Female
- The Impact of the "WOMAN-PRO II Program" on Patients With Vulvar Neoplasia to Minimize Post-surgical Symptom Prevalence
- Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia

### Drugs in development (3)

- Bizalimogene ralaplasmid Phase 2
- Imiquimod Phase 3
- Omiganan Phase 2

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