> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/vaginal-cancer-42756cfb-d483-5500-b61e-9426e803eb1a > Record changed: 2026-11-04 # Vaginal cancer Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** A primary or metastatic malignant neoplasm involving the vagina. Representative examples include carcinomas and sarcomas. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Vaginal cancer **Therapeutic area** Oncology ### Alternative names (18) - vaginal cancer - cancer of vagina - malignant neoplasm of the vagina - malignant neoplasm of vagina - malignant tumor of the vagina - malignant tumor of vagina - malignant tumour of the vagina - malignant tumour of vagina - malignant vagina neoplasm - malignant vagina tumor - malignant vagina tumour - malignant vaginal neoplasm - malignant vaginal tumor - malignant vaginal tumour - vagina cancer - vagina neoplasm - vaginal tumor - vaginal tumour ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Oncology - Reproductive Health Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001402) ## Identifiers **MONDO ID** MONDO:0001402 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001402) **Parent condition** MONDO:0001416 ## Related records ### Broader conditions (16) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - [Female reproductive organ cancer](https://trialight.com/data/condition/female-reproductive-organ-cancer-1207d84e-931f-51b6-90d9-6b2135cdebbb.md) - Female reproductive system disorder - [Female reproductive system neoplasm](https://trialight.com/data/condition/female-reproductive-system-neoplasm-a546c16a-5a0e-51fa-bf62-79ed8ecf0059.md) - Human disease - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - Reproductive system cancer - Reproductive system disorder - Reproductive system neoplasm - Vaginal disorder - Vaginal neoplasm ### Narrower conditions (16) - Adult vagina botryoid embryonal rhabdomyosarcoma - Botryoid-type embryonal rhabdomyosarcoma of the vagina - Childhood vagina botryoid rhabdomyosarcoma - Endometrioid stromal sarcoma of the vagina - Malignant vaginal mixed epithelial and mesenchymal neoplasm - Vagina leiomyosarcoma - Vagina sarcoma - Vaginal adenocarcinoma - Vaginal adenoid cystic carcinoma - Vaginal adenosarcoma - Vaginal carcinoma - Vaginal carcinosarcoma - Vaginal germ cell malignant tumor - Vaginal rhabdomyosarcoma - Vaginal squamous cell carcinoma - Vaginal yolk sac tumor ### Trials (163) - 3D Printed Custom Applicators for HDR BT (DISCO) - A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors - A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer - A Phase I Study of CCI-779 (Temsirolimus) in Combination With Topotecan in Patients With Gynecologic Malignancies - A Phase I Trial Evaluate the Safety and Tolerability Profile of HPV Vaccine - A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers - A Phase II, Single-arm, Multicenter, Prospective Study of Cardunolizumab in Recurrent or Metastatic Vulvar and Vaginal Cancer - A Randomized Controlled Trial of an Online Support Group for Sexual Distress Due to Gynecologic Cancer - A Single-arm, Multicenter Clinical Study of Becotatug Vedotin Combined With Zimberelimab in the Treatment of Recurrent and Metastatic Cervical Cancer, Vulvar Cancer and Vaginal Cancer - A Study of INCB099280 in Combination With Axitinib in Adults With Advanced Solid Tumors - A Study of V503 (A Multivalent Human Papillomavirus \[HPV\] L1 Virus-Like Particle \[VLP\] Vaccine) in Preadolescents and Adolescents (V503-002) - A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006) - [A Study to Evaluate the Immunogenicity and Safety of HPV Vaccine in Healthy Female Participants Aged 9-26 Years in China](https://trialight.com/data/trial/a-study-to-evaluate-the-immunogenicity-and-safety-of-hpv-c83859dc-0c17-4639-bb21-b1aa42234b97.md) - A Study to Evaluate Tolerability and Immunogenicity of V504 Administered Concomitantly With GARDASIL (V504-001)(COMPLETED) - A Survivorship Care Plan for Gynaecological Cancer Patients - A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) - Agnostic Therapy in Rare Solid Tumors - Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity - ASk Questions in GYnecologic Oncology (ASQ-GYO) - Assessment of Sexual Quality of Life Following Local Treatment (Radiotherapy With or Without Surgery) in Patients With HPV-positive Pelvic Cancer: a Descriptive Longitudinal Study ### Drugs in development (34) - Adavosertib Phase 1 - Aldesleukin Phase 2 - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 1 - Becotatug vedotin Phase 2 - Bintrafusp alfa Phase 1 - [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 2 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 1 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 3 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 2 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Phase 1 - [Disitamab vedotin](https://trialight.com/data/asset/disitamab-vedotin-bea2e0f0-afc7-4495-83ca-87eaf4660054.md) Phase 2 - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 1 - [Doxorubicin](https://trialight.com/data/asset/doxorubicin-f556df52-a942-40dd-90f8-e6bb7ff70b4d.md) Phase 1 - [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) Phase 1 - Edodekin alfa Phase 1 - Entinostat Phase 1 - [Fludarabine](https://trialight.com/data/asset/fludarabine-e03241fb-ac4f-4851-ae4f-6e8dad4f1d28.md) Phase 2 - [Human papillomavirus, L1 protein virus like particles](https://trialight.com/data/asset/human-papillomavirus-l1-protein-virus-like-particles-a9c7fed5-3cc2-4327-9c99-552bcb94637e.md) Phase 2 - Imiquimod Phase 2 - Immunocytokine nhs-IL12 Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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