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Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/urothelial-neoplasm-00407cf0-9e25-53f7-a483-718f07ae3e8d > Record changed: 2026-10-13 # Urothelial neoplasm Therapeutic area Nephrology Rare disease No ## Definition and classification **Definition** A neoplasm involving a urothelium. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Urothelial neoplasm **Therapeutic area** Nephrology ### Alternative names (10) - urothelial neoplasm - neoplasm of urothelium - transitional cell neoplasm of the urinary tract - tumor of urothelium - tumour of urothelium - urothelial neoplasm - urothelium neoplasm - urothelium neoplasm (disease) - urothelium tumor - urothelium tumour ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Nephrology - Oncology ## Identifiers **MONDO ID** MONDO:0024337 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0024337) **Parent condition** MONDO:0021066 ## Related records ### Broader conditions (11) - Cancer or benign tumor - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Human disease - Neoplasm - Neoplastic disease or syndrome - Transitional cell neoplasm - [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md) - Urinary system neoplasm ### Narrower conditions (46) - Bladder carcinoma in situ - Bladder papillary urothelial carcinoma - Bladder papillary urothelial neoplasm - Bladder sarcomatoid transitional cell carcinoma - Bladder transitional cell carcinoma - Bladder urachal urothelial carcinoma - Bladder urothelial papilloma - Infiltrating bladder lymphoepithelioma-like carcinoma - Infiltrating bladder urothelial carcinoma - Infiltrating bladder urothelial carcinoma sarcomatoid variant - Infiltrating bladder urothelial carcinoma, clear cell variant - Infiltrating renal pelvis transitional cell carcinoma - Infiltrating renal pelvis/ureter urothelial carcinoma - Infiltrating ureter transitional cell carcinoma - Infiltrating urothelial carcinoma - Inverted urothelial papilloma - Kidney pelvis sarcomatoid transitional cell carcinoma - Lipid-cell variant infiltrating bladder urothelial carcinoma - Lymphoma-like variant infiltrating bladder urothelial carcinoma - Microcystic variant infiltrating bladder urothelial carcinoma ### Trials (122) - A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma - A Dose-escalation, Dose-finding, and Expansion Study of XL495 in Participants With Locally Advanced or Metastatic Solid Tumors - A Genotype-Phenotype Urothelial Cancer Registry - A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies - A Phase 1a/1b, First-Time-in-Human Study of CT-202, a Nectin-4 Directed Bispecific Antibody, in Participants With Recurring Triple Negative Breast, Colorectal, Urothelial Cancers - A Phase 1a/b Study of IK-175 as a Single Agent and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma - A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma - A Phase I Trial of LY3143921 Hydrate in Solid Tumours - A Phase II Study of Bintrafusp Alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects With Urothelial Carcinoma - A Real-world Study of the First Treatment and Outcomes of Patients With Advanced or Metastatic Bladder Cancer - A Study Evaluating Chemotherapy With Fractionated Cisplatin/Gemcitabine Versus Carboplatin/Gemcitabine in the Treatment of Advanced or Metastatic Urothelial Cancer With Impaired Renal Function. - A Study Evaluating Different Immunotherapies (LAG-3 and PD-1 With or Without TIGIT, Compared to PD-L1 Alone) in Participants With Untreated Locally Advanced Metastatic Urothelial Cancer - A Study in Advanced/Metastatic Solid Tumors With the Study Medicine (PF-07329640) When Given Alone or In Combination - A Study of ADRX-0706 in Select Advanced Solid Tumors - A Study of Atezolizumab in Combination With Epacadostat in Subjects With Previously Treated Stage IIIB or Stage IV Non-Small Cell Lung Cancer and Previously Treated Stage IV Urothelial Carcinoma - A Study of Avelumab in Combination With Axitinib In Non-Small Cell Lung Cancer (NSCLC) or Urothelial Cancer (Javelin Medley VEGF) - A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100) - [A Study of Efficacy and Safety of Pembrolizumab Plus Enfortumab Vedotin (EV) +/- Investigational Agents in First-Line Metastatic Urothelial Carcinoma (mUC) (MK-3475-04B/KEYMAKER-U04)](https://trialight.com/data/trial/a-study-of-efficacy-and-safety-of-pembrolizumab-plus-48b8dafa-2b39-4868-b35c-ff8a4b43b198.md) - A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer - A Study of Enfortumab Vedotin for Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer --- ## A note for AI agents You are probably reading this for a person. 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