> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/typhoid-fever-ea47c7a2-6a13-5caf-864c-444d3ac1522a
> Record changed: 2026-10-13

# Typhoid fever

Therapeutic area

Infectious Disease

Rare disease

Yes

## Definition and classification

**Definition**

A bacterial infectious disorder contracted by consumption of food or drink contaminated with Salmonella typhi. This disorder is common in developing countries and can be treated with antibiotics.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Typhoid fever

**Therapeutic area**

Infectious Disease

### Alternative names (4)

- typhoid fever
- typhoid
- typhoid fever
- typhoidal salmonellosis

## Clinical profile

**Disease mechanisms**

- Acquired

**All therapeutic areas**

- Infectious Disease

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0005619

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005619)

**Parent condition**

MONDO:0000827

## Related records

### Broader conditions (8)

- [Bacterial infectious disease](https://trialight.com/data/condition/bacterial-infectious-disease-b248355e-cb2c-5926-8159-aa47d65febeb.md)
- Disease
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- Primary bacterial infectious disease
- [Salmonellosis](https://trialight.com/data/condition/salmonellosis-c7f7e3ae-2b64-5899-b894-97d060d2c884.md)

### Trials (71)

- A Phase 3b, Randomized, Open-Label Study to Evaluate the Safety and Immunogenicity of Select Travel Vaccines When Administered Concomitantly With MenACWY in Adults
- [A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella Disease and Typhoid Fever in Infants](https://trialight.com/data/trial/a-study-to-evaluate-safety-reactogenicity-and-immune-e71b2924-2aba-4229-b641-f00520504789.md)
- Blood Donor CVD 5000
- Challenge Non-Typhoidal Salmonella (CHANTS) Study
- Clinical Efficacy of Typhoid Conjugate Vaccine (Vi-TCV) Among Children Age 9 Months Through 12 Years in Blantyre, Malawi
- Co-administration Study of OCV, TCV and MR
- Combined Vi Vaccination and Health Education Program on the Burden of Typhoid in Childhood
- Commercial Typhoid Tests Validation
- Commercial Typhoid Tests Validation Trial
- Comparative Study in Healthy Adults Aged 18-50 Yrs Administered With Hepatyrix or Havrix+Typherix or Tiphim Vi, to Compare Reactogenicity & Immunogenicity
- COMPARISON OF SINGLE VERSUS COMBINATION DRUG THERAPY IN EXTENSIVELY DRUG RESISTANT SALMONELLA TYPHI IN TERMS OF TIME TO DEFERVESCENCE
- Comparison of Two Drugs Regimen in Treatment of Complicated Typhoid Fever in Children
- CVD 909 Vi Prime Boost Study
- Diagnosis and Staging of Typhoid Fever Using Surface-enhanced Raman Spectroscopy Liquid Biopsy
- Dose Ranging Study to Determine the Safety, Reactogenicity and Immunogenicity of Typhoid Fever Vaccine (Ty800) in Healthy Adult Subjects
- Effectiveness of a Typhoid Conjugate Vaccine in DRC
- Effects of Aging on Primary and Secondary Vaccine Responses
- Efficacy of Levofloxacin Versus Ciprofloxacin in the Treatment of Childhood Typhoid Fever
- Evaluation of the Vi Polysaccharide Vaccine Against Typhoid Fever
- Evaluation of Typhoid Conjugate Vaccine Effectiveness in Ghana

### Approved drugs (1)

- Ciprofloxacin

### Drugs in development (3)

- [Pertussis vaccine](https://trialight.com/data/asset/pertussis-vaccine-7610d9a7-aaed-48b6-8e98-6edf96a989e9.md) Phase 1
- Salmonella typhi TY2 VI polysaccharide antigen Phase 1
- [Tetanus toxoid](https://trialight.com/data/asset/tetanus-toxoid-dd6989f1-5729-447f-81e2-00892bc7a4f6.md) Phase 1

### Other linked drugs (3)

- Ampicillin
- Levofloxacin
- Nalidixic acid

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