> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/type-2-diabetes-mellitus-98e14a90-bb06-5174-90c7-901a0a259fb9
> Record changed: 2026-10-13

# Type 2 diabetes mellitus

Therapeutic area

Metabolic Disease

Rare disease

No

## Definition and classification

**Definition**

A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity.

**Genetic basis**

Yes

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Type 2 diabetes mellitus

**Therapeutic area**

Metabolic Disease

### Alternative names (26)

- type 2 diabetes mellitus
- NIDDM
- T2D
- T2DM
- T2DM - type 2 diabetes mellitus
- adult onset diabetes
- adult-onset diabetes
- diabetes mellitis type 2
- diabetes mellitis type II
- diabetes mellitus, noninsulin-dependent
- diabetes mellitus, noninsulin-dependent, association with
- diabetes mellitus, noninsulin-dependent, late onset
- diabetes mellitus, type 2
- diabetes mellitus, type II
- diabetes, type 2
- insulin resistance, severe, digenic
- non-insulin dependent diabetes
- non-insulin dependent diabetes mellitus
- noninsulin dependent diabetes
- noninsulin-dependent diabetes mellitus
- type 2 diabetes
- type 2 diabetes mellitus
- type 2 diabetes mellitus non-insulin dependent
- type II diabetes
- type II diabetes mellitus

And 1 more, listed on the interactive page.

## Clinical profile

**Severity**

Moderate

### All therapeutic areas (3)

- Endocrinology
- Gastroenterology
- Metabolic Disease

## Identifiers

**MONDO ID**

MONDO:0005148

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005148)

**Parent condition**

MONDO:0005015

## Related records

### Broader conditions (11)

- [Diabetes mellitus](https://trialight.com/data/condition/diabetes-mellitus-1a0391a8-9f84-5600-a2bf-ec97c2229de4.md)
- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Endocrine pancreas disorder
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- [Glucose metabolism disease](https://trialight.com/data/condition/glucose-metabolism-disease-e258cc9e-1eda-56cb-80f3-f4bd7a42bc71.md)
- Human disease
- Metabolic disease
- Pancreas disorder

### Narrower conditions (6)

- Diabetes mellitus, noninsulin-dependent, 1
- Diabetes mellitus, noninsulin-dependent, 2
- Diabetes mellitus, noninsulin-dependent, 3
- Diabetes mellitus, noninsulin-dependent, 4
- Diabetes mellitus, noninsulin-dependent, 5
- Lipoatrophic diabetes

### Trials (10,373)

- -Oleoyl Glycerol is a GPR119 Agonist and Signals GLP-1 Release in Humans.
- : Identification of Non-alcoholic Steato-hepatitis Cases in a Sample of Type 2 Diabetes Patients, with a Disruption of the Liver Function Tests, At the Pointe-à-Pitre University Hospital
- ¡Si, Yo Puedo Control Mi Diabetes!: A Diabetes Self-management Education Program for Hispanic/Latinos
- 'Ai Pono Cooking Demonstrations
- "Can Soluble-CD163 Discriminate Between Healthy and Unhealthy Obese Individuals?"
- "Effect of Dipeptidyl Peptidase IV After Diets in näive Type 2 Diabetic Patients"
- "Effect of High Fat and High Glycemic Diets
- "Effect of Omega-3 Supplementation as Add on Therapy on Glycemic Control and Lipid Profile in Type2 Diabetes Mellitus."
- "Effectiveness of Supervised and Unsupervised mHealth-based Exercise Interventions on Clinical Outcomes in Adults With Type 2 Diabetes and Obesity Within a Primary Care Context"
- "Efficacy of Once Weekly GLP 1 Analogue: Semaglutide. A Multicenter Experience From Pakistan."
- "Hepatic Substrate Flux Rates in Type 2 Diabetes"
- "Information Technology Methodology for Patient Motivation in Diabetes Management."
- "POWER2DM Evaluation Campaign"
- "Preventing Cardiovascular Ischemic Events and Arresting Their Consequences in Type 2 Diabetic Population
- "Screening for Change: Early Risk Detection and Integrated Prevention for Diabetes and Cardiovascular Diseases in the Marche Region"
- "Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"
- "Shoulder Musculoskeletal Disorders in Type 2 Diabetes Mellitus: Contributing Factors and Rehabilitation Protocol"
- "TAKE TIME" Pioglitazone Reverses Defects in Mitochondrial Biogenesis in Patients With T2DM
- "The Effect of Comprehensive Non-pharmacological Treatment on Metabolic Disorders in Type 2 Diabetic Patients"
- "Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds"

### Approved drugs (52)

- Acarbose
- Albiglutide
- Alogliptin benzoate
- Bexagliflozin
- Biotin
- Bromocriptine mesylate
- Canagliflozin
- Chlorpropamide
- Colesevelam hydrochloride
- Cyanocobalamin
- [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md)
- Dapagliflozin propanediol
- [Dulaglutide](https://trialight.com/data/asset/dulaglutide-71cf82e9-b69c-4c77-af75-01d8d2f9fbb2.md)
- [Empagliflozin](https://trialight.com/data/asset/empagliflozin-09301932-ac0f-4eb7-8d1d-bd13fdbb6ab8.md)
- Ertugliflozin pidolate
- Exenatide
- Fenofibrate
- Fenofibric acid
- [Finerenone](https://trialight.com/data/asset/finerenone-e8453ce2-da00-4096-b589-903ae1d466ba.md)
- Folic acid

### Drugs in development (357)

- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 1
- Acetylcarnitine Phase 2
- Acetylcholine Phase 2
- Acetylcysteine Early phase 1
- Acipimox Phase 2
- Aclimostat Phase 2
- Adomeglivant Phase 2
- ADP-597 Phase 1
- [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 2
- Aldafermin Phase 2
- Aleglitazar Phase 3
- Aliskiren Phase 1
- Allopurinol Phase 3
- Alogliptin Phase 3
- Amantadine Phase 2
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 3
- Ampelopsin Phase 2
- Anagliptin Phase 3
- Arginine Phase 1
- Arhalofenate Phase 2

### Other linked drugs (25)

- Amibegron
- [Anakinra](https://trialight.com/data/asset/anakinra-2c0352ee-cb20-46c5-bd87-6350d9024e75.md)
- Arundic acid
- Cabergoline
- Cetilistat
- Ciprofloxacin
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md)
- Edaglitazone
- Ertiprotafib
- Esomeprazole
- Glisoxepide
- Isosorbide mononitrate
- Losartan potassium
- Luseogliflozin
- Meglitinide
- Mirabegron
- Nitroprusside
- Pentaerythritol tetranitrate
- Polyethylene glycol
- Potassium

---

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