> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/type-1-diabetes-mellitus-c22c640e-5db9-525c-8e4b-8da31250a7a3
> Record changed: 2026-11-04

# Type 1 diabetes mellitus

Therapeutic area

Endocrinology

Rare disease

No

## Definition and classification

**Definition**

A chronic condition characterized by minimal or absent production of insulin by the pancreas.

**Genetic basis**

Yes

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Type 1 diabetes mellitus

**Therapeutic area**

Endocrinology

### Alternative names (25)

- type 1 diabetes mellitus
- diabetes mellitis type 1
- diabetes mellitis type I
- IDDM
- immune mediated diabetes
- insulin dependent diabetes
- Insulin-Dependent Diabetes
- juvenile diabetes
- Newly Diagnosed Type 1 Diabetes
- Stage 1 Type 1 Diabetes
- Stage 2 Type 1 Diabetes
- Stage 3 Type 1 Diabetes
- T1D
- T1DM
- type 1 diabetes
- Type 1 Diabetes (Juvenile Onset)
- Type 1 Diabetes (T1D)
- Type 1 Diabetes,
- Type 1 Diabetes, Pregnancy
- type I diabetes
- type I diabetes mellitus
- Type-1 Diabetes
- Type-1-Diabetes
- Type1 Diabetes
- Type1diabetes

## Clinical profile

**Severity**

Moderate

### All therapeutic areas (4)

- Endocrinology
- Gastroenterology
- Immunology
- Metabolic Disease

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005147)

## Identifiers

**MONDO ID**

MONDO:0005147

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005147)

**Parent condition**

MONDO:0000569

## Related records

### Broader conditions (15)

- [Autoimmune disease](https://trialight.com/data/condition/autoimmune-disease-8a8fd8aa-2d04-5f24-b839-ba96a70c11e9.md)
- Autoimmune disorder of endocrine system
- Autoimmune disorder of gastrointestinal tract
- [Diabetes mellitus](https://trialight.com/data/condition/diabetes-mellitus-1a0391a8-9f84-5600-a2bf-ec97c2229de4.md)
- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Endocrine pancreas disorder
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- [Glucose metabolism disease](https://trialight.com/data/condition/glucose-metabolism-disease-e258cc9e-1eda-56cb-80f3-f4bd7a42bc71.md)
- Human disease
- [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md)
- [Metabolic disease](https://trialight.com/data/condition/metabolic-disease-3d73c19d-b8c8-5be8-add5-77c7d794dacd.md)
- Pancreas disorder

### Narrower conditions (1)

- Latent autoimmune diabetes in adults

### Trials (3,830)

- ¿Can mySugr App Improve Knowledge and Self-management of People With Type 1 Diabetes Mellitus?
- "FEXIS": (Feasibility of an Extended Wear CSII Set in Participants With T1DM)
- "MiniMed 640G System" User Evaluation With the Question of Reducing the Rate of Hypoglycemia
- "MyPlan" - Individualized Planned Eating Patterns for Adolescents With Type 1 Diabetes
- "Perception, Knowledge, and Attitudes of Educational Staff Regarding the Care of Children With Type 1 Diabetes: Evaluation of the Educational Program"
- "POWER2DM Evaluation Campaign"
- "Sexual Activity and Hypoglycemia Risk in Adults With Type 1 or Type 2 Diabetes Using Insulin Therapy and Continuous Glucose Monitoring"
- "Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds"
- 11C-5-HTP PET in Clinical Islet Transplantation
- 12 Week,Comparing Safety of HMR1964 & Insulin Aspart Used in Continuous Subcutaneous Infusion in Type 1 Diabetes.
- 21 Day Comparison of Continuous Insulin Infusion Using HDV Insulin to Standard Insulin in Type 1 Diabetes Mellitus
- 24-hour Movement Behaviors in Adults With Type 1 Diabetes
- 24/7 Closed-loop in Older Subjects With Type 1 Diabetes
- 32 Week, Open, Randomized, 2 Way Cross Over Multicentre Trial to Compare Safety & Efficacy of Combination of HOE901 Insulin Analogue Once Daily at Bedtime + Lispro Insulin Before Meals vs NPH Insulin (Twice a Day) + Regular in Type 1 Diabetes Mellitus
- 4T Sustainability Program
- 5-MTHF Supplementation for Treatment of Type 1 Diabetes Patients
- 52 Week Trial of Liraglutide in Type 1 Diabetes
- 6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes
- A 12-week Pilot Nutrition Intervention for Children With New Diagnosis of Stage 3 Type 1 Diabetes (T1D)
- A 2-Month Safety Follow-Up Trial

### Approved drugs (6)

- Dasiglucagon hydrochloride
- Insulin detemir
- [Insulin glargine](https://trialight.com/data/asset/insulin-glargine-8aa23d8d-fb05-42b5-b490-2e4b67136155.md)
- [Insulin icodec](https://trialight.com/data/asset/insulin-icodec-fa77ad93-ab76-47ee-8df1-57e5650af79a.md)
- Sotagliflozin
- Teplizumab

### Drugs in development (322)

- .ALPHA.1-proteinase inhibitor human Phase 2
- [Abatacept](https://trialight.com/data/asset/abatacept-a318efa4-5922-464c-8f45-90c18515f1c5.md) Phase 2
- Abrocitinib Phase 2
- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 2
- [Acetazolamide](https://trialight.com/data/asset/acetazolamide-a53ca950-beb6-4a09-9501-5e79acab15cc.md) Phase 1
- Acipimox Phase 3
- Adakitug Phase 1
- [Adalimumab](https://trialight.com/data/asset/adalimumab-77d73b6e-cb34-48b5-9716-a71bee4e5e02.md) Phase 1
- Adomeglivant Phase 1
- Afasevikumab Phase 1
- Alagebrium Phase 2
- Albiglutide Phase 2
- Aldesleukin Phase 2
- Alefacept Phase 2
- Alemtuzumab Phase 2
- [Alirocumab](https://trialight.com/data/asset/alirocumab-94bb5dc8-32f2-4ed6-a82e-b554472e2cd5.md) Phase 3
- Almagate Phase 2
- Alprazolam Phase 1
- [Aluminum hydroxide](https://trialight.com/data/asset/aluminum-hydroxide-a0230a1f-a5e2-439f-baa2-2b988b59e46d.md) Phase 2
- Amitriptyline Phase 2

### Other linked drugs (34)

- Adenosine
- Alanine
- Aspartic acid
- Avexitide
- Beta carotene
- Carnitine
- Clotrimazole
- CO-trimoxazole
- Colesevelam hydrochloride
- Darbepoetin alfa
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md)
- Diazoxide
- [Epinephrine](https://trialight.com/data/asset/epinephrine-bdf4cabf-fe3e-447b-8984-310f4baf125a.md)
- Epoetin alfa
- Epoetin beta
- Ferumoxytol
- [Fludrocortisone](https://trialight.com/data/asset/fludrocortisone-3946cc44-a0b0-4f1a-8a16-1ed2a282469c.md)
- [Formoterol](https://trialight.com/data/asset/formoterol-1c4f9fc6-da8f-4ea7-b9d7-7327267ca099.md)
- Glutamine
- Levomefolic acid

---

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