> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/triple-negative-breast-carcinoma-059174a2-9b5f-5234-90b9-4a4fee6eb9bb > Record changed: 2026-10-13 # Triple-negative breast carcinoma Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** An invasive breast carcinoma which is negative for expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Triple-negative breast carcinoma **Therapeutic area** Oncology ### Alternative names (4) - triple-negative breast carcinoma - triple-negative breast cancer - triple-negative breast carcinoma - triple-receptor negative breast cancer ## Clinical profile **All therapeutic areas** - Oncology **Severity** Severe ## Identifiers **MONDO ID** MONDO:0005494 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005494) **Parent condition** MONDO:0000616 ## Related records ### Broader conditions (20) - [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md) - Breast carcinoma - Breast carcinoma by gene expression profile - [Breast disorder](https://trialight.com/data/condition/breast-disorder-c24c48eb-9ec6-54b1-80b7-1e9cec90eba4.md) - [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Estrogen-receptor negative breast cancer - Her2-receptor negative breast cancer - Human disease - Neoplasm - Neoplasm of thorax - Neoplastic disease or syndrome - Progesterone-receptor negative breast cancer - [Thoracic cancer](https://trialight.com/data/condition/thoracic-cancer-bb0f3b17-0261-5157-830c-759d6c71e62b.md) ### Narrower conditions (1) - Basal-like breast carcinoma ### Trials (1,212) - "neoBREASTIM": Atezolizumab Plus RP1 Oncolytic Immunotherapy in the NeoAdjuvant Setting of Triple-Negative Breast Cancer - \[18F\]-DPA-714 PET/CT (Positron Emission Tomography/Computerized Tomography) in Triple Negative Breast Cancers - 177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors - 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors - 18F-FSPG PET/CT for Cancer Patients on Therapy - 2nd Line Treatment With Pemetrexed and Sorafenib for Recurrent or Metastatic Triple Negative Breast Cancer - 68Ga-FAPI-46 PET/CT for Predicting Histological Response in Triple-negative Breast Cancer (FAP-IT) - 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) - A Beta-only IL-2 ImmunoTherapY Study - A Biomarker Screening Protocol for Participants With Solid Tumors - A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer - A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer - A Clinical Study of 9MW2821 (and PD-1 Inhibitor) in Locally Advanced or Metastatic Triple-Negative Breast Cancer - A Clinical Study of Boserolimab (MK-5890) With Pembrolizumab and Chemotherapy in People With Early Triple-Negative Breast Cancer (MK-5890-003) - [A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)](https://trialight.com/data/trial/a-clinical-study-of-sacituzumab-tirumotecan-sac-tmt-mk-2870-47421f86-889b-4c0b-a65c-14ed97707a1e.md) - A Clinical Study of the Efficacy and Safety of Chidamide in Combination With Camrelizumab and Carboplatin or Capecitabine in the Second and Third Line Treatment of Relapsed/Metastatic Triple-negative Breast Cancer - A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors - A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors - A Clinical Trial Comparing Gemcitabine and Carboplatin With and Without P276-00 in Subjects With Metastatic Triple Negative Breast Cancer, With a Run-in of Escalating Dose of P276-00 Added to Gemcitabine and Carboplatin - A Clinical Trial of SHR-A1811 in the Treatment of Triple-negative Breast Cancer ### Approved drugs (2) - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) - [Sacituzumab govitecan](https://trialight.com/data/asset/sacituzumab-govitecan-fce40bcf-4086-4a36-a9b1-767dee19e0ba.md) ### Drugs in development (135) - Adagloxad simolenin Phase 3 - Adavosertib Phase 1 - [Alpelisib](https://trialight.com/data/asset/alpelisib-0b0ae0f7-4313-42ef-bbbe-3280ed5ea15c.md) Phase 2 - [Anastrozole](https://trialight.com/data/asset/anastrozole-327e05a9-e5b7-41d1-a335-bd8a46453b55.md) Phase 2 - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 2 - AZD-8186 Phase 1 - Bavituximab Phase 2 - Bemcentinib Phase 2 - Berzosertib Phase 1 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - Bexarotene Phase 1 - [Binimetinib](https://trialight.com/data/asset/binimetinib-f5914744-65e2-4d8c-8482-9f51a406315e.md) Phase 2 - Bintrafusp alfa Phase 1 - Brostallicin Phase 2 - Bulumtatug fuvedotin Phase 1 - Camrelizumab Phase 3 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 3 - [Capivasertib](https://trialight.com/data/asset/capivasertib-935ebe6a-a1c8-413b-8259-07e301a25a61.md) Phase 2 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3 - [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2 ### Other linked drugs (2) - [Gilvetmab](https://trialight.com/data/asset/gilvetmab-4079fd36-a0c4-44f0-96bd-7888b5841291.md) - Sacituzumab --- ## A note for AI agents You are probably reading this for a person. 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