> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/thyroid-cancer-44afb6a8-b88e-5e18-b9fd-7b51661c2c23
> Record changed: 2026-10-13

# Thyroid cancer

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

A malignant neoplasm involving the thyroid gland

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Thyroid cancer

**Therapeutic area**

Oncology

### Alternative names (23)

- thyroid cancer
- neoplasm of thyroid gland
- thyroid gland neoplasm
- cancer of thyroid gland
- malignant neoplasm of the thyroid
- malignant neoplasm of the thyroid gland
- malignant neoplasm of thyroid
- malignant neoplasm of thyroid gland
- malignant thyroid gland neoplasm
- malignant thyroid gland tumor
- malignant thyroid gland tumour
- malignant thyroid neoplasm
- malignant thyroid tumor
- malignant thyroid tumour
- malignant tumor of the thyroid
- malignant tumor of the thyroid gland
- malignant tumor of thyroid
- malignant tumor of thyroid gland
- malignant tumour of the thyroid
- malignant tumour of the thyroid gland
- malignant tumour of thyroid
- malignant tumour of thyroid gland
- thyroid gland cancer

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Endocrinology
- Oncology

## Identifiers

**MONDO ID**

MONDO:0002108

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002108)

**Parent condition**

MONDO:0015074

## Related records

### Broader conditions (13)

- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Endocrine gland neoplasm
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- Human disease
- Malignant endocrine neoplasm
- Neoplasm
- Neoplastic disease or syndrome
- Thyroid gland disorder
- [Thyroid tumor](https://trialight.com/data/condition/thyroid-tumor-fc2bab9d-d468-5acb-8a62-e5f68e538979.md)

### Narrower conditions (39)

- Columnar cell variant thyroid gland papillary carcinoma
- Differentiated thyroid carcinoma
- Familial medullary thyroid carcinoma
- Familial nonmedullary thyroid carcinoma
- Familial papillary or follicular thyroid carcinoma
- Familial papillary thyroid carcinoma with renal papillary neoplasia
- Intrathyroid thymic carcinoma
- Medullary thyroid gland carcinoma
- Multicentric papillary thyroid carcinoma
- Multiple endocrine neoplasia type 2
- [Multiple endocrine neoplasia type 2A](https://trialight.com/data/condition/multiple-endocrine-neoplasia-type-2a-d7f126fe-0dc5-563d-b580-bd17f918d5c1.md)
- Multiple endocrine neoplasia type 2B
- Papillary thyroid Microcarcinoma
- Tall cell variant thyroid gland papillary carcinoma
- Thyroid cancer, nonmedullary, 1
- Thyroid cancer, nonmedullary, 2
- Thyroid cancer, nonmedullary, 3
- Thyroid cancer, nonmedullary, 4
- Thyroid cancer, nonmedullary, 5
- Thyroid carcinoma, nonmedullary, with or without cell oxyphilia

### Trials (454)

- 11C-Acetate PET/CT Non-FDG-Avid Tumors
- 177Lu-CTR-FAPI for the Treatment of Thyroid Cancer
- 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer
- 18F Labeled FAP Targeted Molecular Probe in Early Tumor Diagnosis
- 3-D Super Resolution Ultrasound Microvascular Imaging
- 99mTc Sestamibi Scans In Thyroglobulin Positive Scan Negative Differentiated Thyroid Cancer (DTC) Patients
- A Brief Video Intervention to Improve Patient Outcomes Following Radioiodine Treatment
- A Clinical Trial of KVA12123 \[TBS-2025\] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)
- A Continuation Study Using Sunitinib Malate For Patients Leaving Treatment On A Previous Sunitinib Study.
- A Follow-up Study of Women Evaluated and Treated for Infertility
- A Multicenter Phase II Pilot Open Label
- A Multicenter Trial of PLA vs. Surgery for Treating PTMC
- A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC)
- A New Surgical Strategy to Protect the Inferior Parathyroid
- A Phase 2, Open-label Study of AMG 706 to Treat Subjects With Locally Advanced or Metastatic Thyroid Cancer
- A Phase I/II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer and Incurably Poorly Differentiated or Radioidodine Refractory Differentiated Thyroid Cancer
- A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors
- A Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and Hypopharynx
- A Pilot Clinical Trial for Poorly Differentiated Thyroid Cancer - Correlation to Retinoid and Peroxisome-proliferator-activated Receptor (PPARy) Expression
- A Prospective, Multi-Centre Trial of TKI Redifferentiation Therapy in Patients With RAIR Thyroid Cancer (I-FIRST Study)

### Approved drugs (8)

- Cabozantinib S-malate
- Lenvatinib mesylate
- [Levothyroxine sodium](https://trialight.com/data/asset/levothyroxine-sodium-748a279d-1239-41f1-b758-863bd96e359b.md)
- [Selpercatinib](https://trialight.com/data/asset/selpercatinib-b5343bcc-f751-4491-a1dd-3c8536f333da.md)
- Sodium iodide I 131
- Sorafenib tosylate
- Thyrotropin alfa
- Vandetanib

### Drugs in development (77)

- [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 2
- [Adalimumab](https://trialight.com/data/asset/adalimumab-77d73b6e-cb34-48b5-9716-a71bee4e5e02.md) Phase 1
- [Adebrelimab](https://trialight.com/data/asset/adebrelimab-047820dd-1777-483d-90ab-dd5fc86f78f6.md) Phase 2
- Aldesleukin Phase 1
- [Benmelstobart](https://trialight.com/data/asset/benmelstobart-2bff71aa-d2ac-4a5a-9949-c935954a2314.md) Phase 2
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2
- Bexarotene Early phase 1
- Buparlisib Phase 2
- [Cabozantinib](https://trialight.com/data/asset/cabozantinib-e69f9fa7-bbbc-4e52-b0df-6073598de2a7.md) Phase 3
- Camrelizumab Phase 2
- [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 2
- [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3
- [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2
- Catequentinib hydrochloride Phase 2
- Ceritinib Phase 2
- [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2
- CM-4307 Phase 3
- Crolibulin Phase 1
- [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 2
- Dabrafenib Phase 3

### Other linked drugs (1)

- [Charcoal, activated](https://trialight.com/data/asset/charcoal-activated-74974a11-0327-42be-ba92-123123e02c3a.md)

---

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