> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/thymic-carcinoma-3ad17495-546a-5b2e-a723-d8cde5d18fc3 > Record changed: 2026-11-04 # Thymic carcinoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** Thymic carcinoma (TC) is a type of thymic epithelial neoplasm characterized by a high malignant potential. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Thymic carcinoma **Therapeutic area** Oncology ### Alternative names (20) - thymic carcinoma - Advanced Thymic Carcinoma - carcinoma of thymus - Invasive Thymoma and Thymic Carcinoma - Locally Advanced Thymic Carcinoma - malignant thymoma - Metastatic Thymic Carcinoma - Recurrent Malignant Thymoma - Recurrent Thymic Carcinoma - thymic carcinoma (excluding well differentiated thymic carcinoma) - thymic carcinoma excluding well differentiated thymic carcinoma - Thymoma Malignant Recurrent - thymoma type C - thymoma, malignant - thymoma, malignant (morphologic abnormality) - thymoma, type C (morphologic abnormality) - thymus carcinoma - type C thymoma - Unresectable Thymic Carcinoma - THYC ## Clinical profile **Severity** Severe ### All therapeutic areas (4) - Endocrinology - Hematology - Immunology - Oncology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006451) ## Identifiers **MONDO ID** MONDO:0006451 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006451) **Parent condition** MONDO:0002586 ## Related records ### Broader conditions (21) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Endocrine gland neoplasm - [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md) - Epithelial neoplasm - Hematologic disorder - [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md) - Human disease - Immune system cancer - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Malignant endocrine neoplasm - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - Thymic epithelial neoplasm - Thymus cancer - Thymus gland disorder ### Narrower conditions (18) - Invasive malignant thymoma - Lymphoepithelioma-like thymic carcinoma - Malignant type AB thymoma - Moderately-differentiated thymic neuroendocrine carcinoma - Papillary thymic adenocarcinoma - Poorly differentiated thymic neuroendocrine carcinoma - Thymic adenosquamous carcinoma - Thymic basaloid carcinoma - Thymic large cell neuroendocrine carcinoma - Thymic mucoepidermoid carcinoma - Thymic neuroendocrine carcinoma - Thymic sarcomatoid carcinoma - Thymic undifferentiated carcinoma - Thymus clear cell carcinoma - Thymus gland adenocarcinoma - Thymus small cell carcinoma - Thymus squamous cell carcinoma - Well-differentiated thymic neuroendocrine carcinoma ### Trials (47) - A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, Malignancies - A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies - A Phase II Trial of Sacituzumab Govitecan in Patients With Advanced Thymic Epithelial Tumors - A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy - A Study of KN046 in Patients With Thymic Carcinoma Who Failed Immune Checkpoint Inhibitors - [A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers](https://trialight.com/data/trial/a-study-of-safety-and-efficacy-of-kfa115-alone-and-in-combo-6000ed6a-dc09-49ab-af31-2539b9b4fb32.md) - A Study of Sunitinib in Patients With Metastatic or Recurrent Thymic Carcinoma - A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors - A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma - Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors - Belinostat (PXD101) to Treat Tumors of the Thymus at an Advanced Stage - Carboplatin Combined With Paclitaxel in Treating Patients With Advanced Thymoma - CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors - Chemotherapy Plus Cetuximab Followed by Surgical Resection in Patients With Locally Advanced or Recurrent Thymoma or Thymic Carcinoma - Defining the Clinical Potential of Mass Response As a Biomarker for Patient Tumor Sensitivity to Drugs - Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S - Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy - Electrocautery Resection Combined With HITHOC for Thymic Epithelial Tumors With Pleural Metastasis - Genomic Profiling of Nodular Thyroid Disease and Thyroid Cancer - Hypofractionated Adjuvant Radiotherapy for Thymic Epithelial Tumors ### Drugs in development (56) - Amrubicin Phase 2 - Amrubicin hydrochloride Phase 2 - Antilymphocyte immunoglobulin (horse) Phase 2 - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 2 - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 2 - Belinostat Phase 2 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - Bintrafusp alfa Phase 2 - Busulfan Phase 2 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 1 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 2 - [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2 - [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 1 - [Cetuximab](https://trialight.com/data/asset/cetuximab-a1f8c65c-bae1-4b77-9491-dca37aeeaa3c.md) Phase 2 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2 - Cixutumumab Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 2 - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 2 - [Domvanalimab](https://trialight.com/data/asset/domvanalimab-a06209c7-7e05-4bb9-92e2-610f995f4a6b.md) Phase 2 - [Doxorubicin](https://trialight.com/data/asset/doxorubicin-f556df52-a942-40dd-90f8-e6bb7ff70b4d.md) Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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