> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/thrombotic-disease-3f54ef10-d2ed-524f-a020-8ecb2eb62a52 > Record changed: 2026-10-13 # Thrombotic disease Therapeutic area Vascular Medicine Rare disease No ## Definition and classification **Definition** The formation of a blood clot in the lumen of a vessel or heart chamber; causes include coagulation disorders and vascular endothelial injury. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Thrombotic disease **Therapeutic area** Vascular Medicine ### Alternative names (9) - thrombotic disease - Clots, blood - Thromboses - blood Clots - blood clot - clot, blood - thrombosis - thrombotic disorder - thrombus ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Cardiology - Vascular Medicine ## Identifiers **MONDO ID** MONDO:0000831 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0000831) **Parent condition** MONDO:0005385 ## Related records ### Broader conditions (5) - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Human disease - Vascular disorder ### Narrower conditions (13) - Acquired purpura fulminans - Carotid artery thrombosis - Cavernous sinus thrombosis - Coronary thrombosis - Heparin-induced thrombocytopenia - Intracranial sinus thrombosis - Intracranial thrombosis - Isolated mesenteric vein thrombosis - Isolated splenic vein thrombosis - Lateral sinus thrombosis - Marantic endocarditis - Portal vein thrombosis - Sagittal sinus thrombosis ### Trials (1,010) - "Follow-up of Midlines Placed Outside the Intensive Care Unit: What Side Effects? An Observational Study" - \[64Cu\]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy - A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation - A Clinical Trial of IntensiVE Dialysis - A Cohort Study With 100 Subjects Having a Primary Total Knee Replacement, Taking Pradax Post Discharge for Ten Days - A Comparison of Certoparin and Unfractionated Heparin in the Prevention of Thromboembolic Events in Acutely Ill Medical Patients - A Complex Contraception Registry - A Dose Escalation and Safety Study of Plasmin (Human) In Acute Lower Extremity Native Artery or Bypass Graft Occlusion - A First-in Human Study of ARD001 in Healthy Volunteers and People With Hemophilia A - A Multicenter Study to Evaluate the Effects of a 91-Day Extended Cycle Oral Contraceptive on Hemostatic Parameters in Healthy Women - A Multinational Study to Evaluate the Effects of a 28-Day Oral Contraceptive on Hemostatic Parameters in Healthy Women - A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance Imaging for the Detection of Intracardiac Thrombus - A Novel Point-to-care Method for Fast Evaluation of Viscoelastic Hemostasis Analysis - A Pharmacokinetics, Pharmacodynamics and Safety Study of Single Dose of Rivaroxaban in Participants With End-Stage Renal Disease (ESRD) on Maintenance Hemodialysis - A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SRSD107 in Healthy Chinese Subjects - A Phase 1 Study to Evaluate the Safety, Tolerability, PK/PD of SRSD107 in Healthy Participants - A Phase 2 Pilot Study of Apixaban for the Prevention of Thromboembolic Events in Patients With Advanced (Metastatic) Cancer - A Phase 2b Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty - A Phase 3 Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty - A Phase I SAD/MAD and Liver Effect Study of Vitalangio in Venous Thromboembolism Patients . ### Approved drugs (55) - Abciximab - Acenocoumarol - Aloxiprin - [Alteplase](https://trialight.com/data/asset/alteplase-89461f67-4f40-4a00-ae4c-727752018887.md) - Anagrelide hydrochloride - Anistreplase - Antithrombin III human - [Apixaban](https://trialight.com/data/asset/apixaban-9e91f03a-6eac-4da8-9f08-88d740399be5.md) - Argatroban - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) - Betrixaban - Bivalirudin - Cangrelor - Cangrelor tetrasodium - Caplacizumab - Cilostazol - Clopidogrel - Dabigatran etexilate - Dalteparin sodium - Danaparoid sodium ### Drugs in development (81) - Acetylcysteine Phase 3 - Alfimeprase Phase 3 - Amediplase Phase 3 - Ancrod Phase 3 - Atecegatran metoxil Phase 2 - Avidin Phase 3 - AZD-8165 Phase 1 - Bemiparin Phase 3 - Beraprost Phase 2 - Bervastatin Phase 2 - BMS-962212 Phase 1 - BMS-986120 Phase 1 - BMS-986141 Phase 2 - Brinolase Phase 2 - Busulfan Phase 3 - Carbaspirin calcium Phase 2 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 2 - Cloricromen Phase 2 - Clorindione Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3 ### Other linked drugs (10) - AZD-6482 - Biciromab - Dextran - Domitroban - Fradafiban - Isoquercetin - Itazigrel - [Lansoprazole](https://trialight.com/data/asset/lansoprazole-1f580c6f-7852-4af6-bdcc-8a5822477b51.md) - Satigrel - Vonoprazan fumarate --- ## A note for AI agents You are probably reading this for a person. 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